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Snx2 (NM_026386) Mouse Untagged Clone
CAT＃: MC217261
Snx2 (untagged) - Mouse sorting nexin 2 (Snx2), (10ug)
CNY 6,650.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 0610030A03Rik |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC217261 representing NM_026386
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGGCCGAGAGGGAGCCTCCTCCGCTGGGGGACGTGAAGCCCACAGACTTTGAGGAGCTGGAGGACG GAGAGGACCTGTTCACCAGCACCGTCTCCACCCTTGAGTCAAGTCCATCATCTCCCGAACCAGCCAGTCT CCCTGCAGAAGATATCAGTGCAAACTCTAATGGCTCCAAACCTGTAGAAGTTGTCCTAGACGATGACAGA GAAGATCTTTTCGCAGAAGCCACAGAAGAGGTGTCCTTGGACAGTCCCGAAAGAGAGCTCATCCTGTCCT CCGAGCCGTCTCCTGCGGTCACCCCTGTCACTCCCACCACACTCATTGCTCCTAGAATCGAATCAAAGAG TATCTCTGCTCCAGTCATCTTTGACAGATCCAGGGACGAGATTGAAGAAGAAGCAAATGGAGATATTTTT GATATAGAAATTGGTGTGTCAGATCCGGAAAAAGTTGGTGATGGCATGAATGCTTACATGGCATATAGAG TAACAACAAAGACTTCTCTTTCCATGTTCAGTAAGAGTGAATTTTCAGTCAAAAGAAGATTCAGTGACTT TCTTGGTTTGCATAGCAAATTAGCAAGCAAATATTTACATGTTGGTTACATCGTGCCACCCGCTCCAGAA AAGAGTATAGTAGGTATGACCAAGGTCAAAGTAGGTAAAGAAGATTCATCATCCACTGAGTTTGTAGAAA AACGAAGAGCGGCACTGGAGAGGTATCTTCAGAGAACAGTAAAGCATCCGACATTGCTTCAGGATCCTGA CTTAAGGCAGTTTTTGGAAAGCTCAGAGCTGCCGAGAGCAGTTAATACGCAGGCTCTGAGTGGAGCAGGA ATATTGAGGATGGTGAACAAGGCTGCCGACGCTGTCAACAAAATGACAATCAAGATGAATGAATCGGATG CATGGTTTGAAGAAAAGCAACAGCAATTTGAGAATCTTGACCAGCAACTTCGGAAACTTCATGCCAGTGT TGAAGCCTTGGTCTGTCATAGAAAAGAACTTTCAGCCAACACAGCCGCCTTTGCTAAGAGTGCTGCCATG CTAGGTAATTCTGAGGACCACACTGCGCTCTCTAGAGCTTTGTCTCAGCTGGCAGAGGTTGAGGAGAAGA TAGACCAGTTACATCAAGAGCAAGCTTTTGCTGACTTTTACATGTTCTCAGAACTTCTTAGTGACTACAT TCGTCTCATTGCTGCAGTGAAAGGTGTGTTTGACCATCGGATGAAGTGCTGGCAGAAATGGGAAGATGCT CAAATTACCTTGCTCAAAAAACGTGAAACTGAGGCAAAAATGATGGTTGCTAACAAGCCAGATAAAATTC AACAAGCTAAAAACGAGATAAGAGAGTGGGAGGCGAAAGTACAACAAGGAGAGAGAGATTTTGAGCAGAT CTCTAAAACAATTCGAAAAGAAGTGGGAAGATTTGAGAAAGAACGAGTGAAAGATTTTAAAGCTGTTATC ATCAAGTACTTGGAGTCATTAGTACAAACACAGCAACAGCTGATAAAGTACTGGGAGGCATTCCTACCTG AAGCCAAAGCCATTGCCTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_026386 |
| Insert Size | 1560 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_026386.1, NP_080662.1 |
| RefSeq Size | 2013 bp |
| RefSeq ORF | 1560 bp |
| Locus ID | 67804 |
| UniProt ID | Q9CWK8 |
| Gene Summary | Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC). Can sense membrane curvature and has in vitro vesicle-to-membrane remodeling activity. Required for retrograde endosome-to-TGN transport of TGN38. Promotes KALRN- and RHOG-dependent but retromer-independent membrane remodeling such as lamellipodium formation; the function is dependent on GEF activity of KALRN (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG208317 | Snx2 (tGFP-tagged) - Mouse sorting nexin 2 (Snx2) |
CNY 4,940.00 |
|
| MR208317 | Snx2 (Myc-DDK-tagged) - Mouse sorting nexin 2 (Snx2) |
CNY 3,872.00 |
|
| MR208317L3 | Lenti ORF clone of Snx2 (Myc-DDK-tagged) - Mouse sorting nexin 2 (Snx2) |
CNY 6,370.00 |
|
| MR208317L4 | Lenti ORF clone of Snx2 (mGFP-tagged) - Mouse sorting nexin 2 (Snx2) |
CNY 6,370.00 |
