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Nr5a2 (NM_001159769) Mouse Untagged Clone
CAT＃: MC216985
Nr5a2 (untagged) - Mouse nuclear receptor subfamily 5, group A, member 2 (Nr5a2), transcript variant 2, (10ug)
CNY 6,460.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AU020803; D1Ertd308e; Ftf; LRH-1; UF2-H3B |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC216985 representing NM_001159769
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCTGCCCAAAGTGGAGACGGAAGCCCCAGGACTGGTCCGATCGCATGGGGAACAGGGGCAGATGCCAG AAAACATGCAAGTGTCTCAATTTAAAATGGTGAATTACTCCTATGATGAAGATCTGGAAGAGCTATGTCC TGTGTGTGGCGATAAAGTGTCTGGGTACCATTACGGTCTCCTCACGTGCGAAAGCTGCAAGGGTTTTTTT AAGCGAACTGTCCAAAACCAAAAAAGGTACACGTGCATAGAGAACCAGAATTGCCAAATTGACAAAACGC AGAGAAAACGATGTCCCTACTGTCGATTCAAAAAATGTATCGATGTTGGGATGAAGCTGGAAGCCGTAAG AGCCGACCGCATGCGAGGGGGCAGAAATAAGTTTGGGCCAATGTACAAGAGAGACAGGGCTTTGAAGCAG CAGAAGAAAGCCCTCATTCGAGCCAATGGACTTAAGCTGGAAGCCATGTCTCAGGTGATCCAAGCAATGC CCTCAGACCTGACCTCTGCAATTCAGAACATTCATTCCGCCTCCAAAGGCCTACCTCTGAGCCATGTAGC CTTGCCTCCGACAGACTATGACAGAAGTCCCTTTGTCACATCTCCCATTAGCATGACAATGCCACCTCAC AGCAGCCTGCATGGTTACCAACCCTATGGTCACTTTCCTAGTCGGGCCATCAAGTCTGAGTACCCAGACC CCTACTCCAGCTCACCTGAGTCAATGATGGGTTACTCCTACATGGATGGTTACCAGACAAACTCCCCGGC CAGCATCCCACACCTGATACTGGAACTTTTGAAGTGTGAACCAGATGAGCCTCAAGTTCAAGCGAAGATC ATGGCTTACCTCCAGCAAGAGCAGAGTAACCGAAACAGGCAAGAAAAGCTGAGCGCATTTGGGCTTTTAT GCAAAATGGCGGACCAGACCCTGTTCTCCATTGTTGAGTGGGCCAGGAGTAGTATCTTCTTCAGGGAACT GAAGGTTGATGACCAAATGAAGCTGCTTCAAAACTGCTGGAGTGAGCTCTTGATTCTCGATCACATTTAC CGACAAGTGGCGCATGGGAAGGAAGGGACAATCTTCCTGGTTACTGGAGAACACGTGGACTACTCCACCA TCATCTCACACACAGAAGTCGCGTTCAACAACCTCCTGAGTCTCGCACAGGAGCTGGTGGTGAGGCTCCG TTCCCTTCAGTTCGATCAGCGGGAGTTTGTATGTCTCAAGTTCCTGGTGCTGTTCAGCTCAGATGTGAAG AACCTGGAGAACCTGCAGCTGGTGGAAGGTGTCCAAGAGCAGGTGAATGCCGCCCTGCTGGACTACACGG TTTGCAACTACCCACAACAGACTGAGAAATTCGGACAGCTACTTCTTCGGCTACCCGAGATCCGGGCAAT CAGCAAGCAGGCAGAAGACTACCTGTACTATAAGCACGTGAACGGGGATGTGCCCTATAATAACCTCCTC ATTGAGATGCTGCATGCCAAAAGAGCCTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001159769 |
| Insert Size | 1500 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001159769.2, NP_001153241.1 |
| RefSeq Size | 3635 bp |
| RefSeq ORF | 1500 bp |
| Locus ID | 26424 |
| Gene Summary | Nuclear receptor that acts as a key metabolic sensor by regulating the expression of genes involved in bile acid synthesis, cholesterol homeostasis and triglyceride synthesis. Together with the oxysterol receptors NR1H3/LXR-alpha and NR1H2/LXR-beta, acts as an essential transcriptional regulator of lipid metabolism. Plays an anti-inflammatory role during the hepatic acute phase response by acting as a corepressor: inhibits the hepatic acute phase response by preventing dissociation of the N-Cor corepressor complex. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development (By similarity). Activates the transcription of CYP2C38 (PubMed:30555544).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) differs in the 5' UTR and 5' coding region compared to variant 1. The resulting isoform (2) contains a distinct and shorter N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG225372 | Nr5a2 (tGFP-tagged) - Mouse nuclear receptor subfamily 5 group A member 2 (Nr5a2) transcript variant 2, (10ug) |
CNY 6,184.00 |
|
| MR225372 | Nr5a2 (Myc-DDK-tagged) - Mouse nuclear receptor subfamily 5, group A, member 2 (Nr5a2), transcript variant 2 |
CNY 5,610.00 |
|
| MR225372L3 | Lenti ORF clone of Nr5a2 (Myc-DDK-tagged) - Mouse nuclear receptor subfamily 5, group A, member 2 (Nr5a2), transcript variant 2 |
CNY 6,984.00 |
|
| MR225372L4 | Lenti ORF clone of Nr5a2 (mGFP-tagged) - Mouse nuclear receptor subfamily 5, group A, member 2 (Nr5a2), transcript variant 2 |
CNY 7,510.00 |
