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Arhgef4 (NM_183019) Mouse Untagged Clone
CAT＃: MC216714
Arhgef4 (untagged) - Mouse Rho guanine nucleotide exchange factor (GEF) 4 (Arhgef4), (10ug)
CNY 6,270.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 9330140K16Rik; Asef; ENSMUSG00000070955 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC216714 representing NM_183019
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGATGACCAGGAGCTGGGCTTCAAAGCTGGGGATGTCATCGAAGTGATGGATGCCACCAACAGGGAAT GGTGGTGGGGCCGAGTGGCAGATGGCGAGGGGTGGTTCCCTGCCAGCTTTGTACGGCTGCGCGTGAACCA GGATGAGCCCGCGGATGACTATGAGGCCCCGCGGGCCGGGGCTAGAGAGGCCGATGACAGCGGTCCAGAG GCTCAGAGCTGCAAGGACCAGATGCGCACAAATGTCATCAATGAGATCCTCAGCACTGAGCGAGACTACA TCAAGCACCTTCGCGACATCTGCGAGGGCTATGTCCGCCAGTGCCGCAAACGGGAGGATATGTTCAGTGA AGAGCAGCTGCGCACCATCTTTGGGAACATCGAGGACATCTACCGCTGCCAAAAGGCATTTGTGAAGGCT TTGGAGCAGAAGTTCAACACGGAGCGGCCACACCTGAGCGAGTTGGGGGCCTGCTTTCTGGAACACCAAG CAGACTTCCAGATCTATTCTGAGTACTGCAACAACCACCCCAATGCCTGCGTGGAGCTCTCCCGGCTCAC GAAGCTCAGCAAGTACGTGTACTTCTTCGAGGCCTGCCGGCTGCTGCAAAGGATGATTGACATCTCGCTG GATGGCTTTCTGCTGACCCCGGTGCAGAAGATCTGCAAGTATCCCCTCCAGCTGGCGGAGCTGCTCAAGT ACACACACCCCCAGCACAGGGACTTTAAGAATGTTGAAGCTGCCTTGCACGCCATGAAGAATGTGGCCCA GCTCATCAACGAACGGAAACGAAGACTTGAAAACATCGACAAGATTGCTCAGTGGCAGAGCTCCATAGAG GACTGGGAGGGGGAAGACCTTCTGGTCAGGAGCTCGGAACTCATCCACTCGGGGGAGCTGACCCGCGTGA CACAGCCTCAAGCCAGGAGTCAGCAGAGAATGTTTTTTCTCTTTGACCGCCAGCTCATCTACTGTAAAAA GGATCTGCTTCGCCGGGACGTGCTGTACTACAAGGGCCGGCTGGACATGGATGACCTGGAGGTGGTAGAT GTGGAAGATGGGAAGGACCGAGACCTCCATGTGAGTGTCAAGAACGCCTTCCGTCTGTACTGTGGTACCA CGGGGGACAGCCACCTACTGTGTGCCAGGAAGCCAGAACAGAAGCAGCGCTGGCTGAAGGCCTTTGCCAG AGAGAGGGAGCAGGTGCGGCTGGACCAGGAGACAGGCTTCTCCATCACCGAGCTGCAGAGGAAGCAGGCC ATGCTGAACGCCAGCAAGCAGCAGGCCACGGGGAAGCCTAAAGCTGTGGGAAGGCCAGGATACCTGACCC GCCACAAGCATCCATCATTGCCTGCCAGCCGGCCCCAGCAGCAAGTGTTGGTGCTAGCAGAGCCCAGGCG GAAGCCATCTAACTTCTGGCACAGCATCAGCAGACTGGCGCCTTTCCGCAAGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_183019 |
| Insert Size | 1455 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_183019.2, NP_898840.2 |
| RefSeq Size | 2738 bp |
| RefSeq ORF | 1455 bp |
| Locus ID | 226970 |
| UniProt ID | Q7TNR9 |
| Gene Summary | Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion (By similarity). Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.[UniProtKB/Swiss-Prot Function] |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG222131 | Arhgef4 (tGFP-tagged) - Mouse Rho guanine nucleotide exchange factor (GEF) 4 (Arhgef4), (10ug) |
CNY 4,750.00 |
|
| MR222131 | Arhgef4 (Myc-DDK-tagged) - Mouse Rho guanine nucleotide exchange factor (GEF) 4 (Arhgef4) |
CNY 3,656.00 |
|
| MR222131L3 | Lenti ORF clone of Arhgef4 (Myc-DDK-tagged) - Mouse Rho guanine nucleotide exchange factor (GEF) 4 (Arhgef4) |
CNY 6,180.00 |
|
| MR222131L4 | Lenti ORF clone of Arhgef4 (mGFP-tagged) - Mouse Rho guanine nucleotide exchange factor (GEF) 4 (Arhgef4) |
CNY 6,180.00 |
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