Arhgef4 Rabbit Polyclonal Antibody

CAT#: TA357571

Arhgef4 Antibody - N-terminal region



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CNY 5,250.00


货期*
6周

规格
    • 100 ul

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beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
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Specifications

Product Data
Applications WB
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Immunogen The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Arhgef4
Specificity Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Homology: Cow: 79%; Dog: 93%; Guinea Pig: 92%; Horse: 86%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 100%
Formulation Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration lot specific
Purification Affinity Purified
Conjugation Unconjugated
Storage Condition For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted Protein Size 57kDa
Gene Name Rho guanine nucleotide exchange factor (GEF) 4
Background Arhgef4 acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion By similarity. It is required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Arhgef4 is involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.
Synonyms ASEF; ASEF1; GEF4; KIAA1112; STM6
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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