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Gabra1 (NM_010250) Mouse Untagged Clone
CAT＃: MC216110
Gabra1 (untagged) - Mouse gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 (Gabra1), (10ug)
CNY 5,990.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | GABAA-alpha1; GABAAR-alpha1; Gabra-1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC216110 representing NM_010250
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAAGAAAAGTCGGGGTCTCTCTGACTATCTTTGGGCCTGGACCCTCATTCTGAGCACACTGTCGGGAA GAAGCTATGGACAGCCCTCCCAAGATGAACTTAAAGACAACACCACTGTCTTCACAAGAATTTTGGACCG ACTGCTGGACGGTTATGACAATCGTCTGAGACCAGGTTTGGGAGAGCGTGTAACTGAAGTGAAGACCGAC ATTTTCGTCACCAGTTTCGGACCAGTTTCAGACCACGATATGGAGTATACAATAGATGTGTTTTTCCGTC AAAGTTGGAAGGATGAAAGATTAAAATTCAAAGGACCCATGACAGTGCTCCGGCTAAACAACCTTATGGC CAGTAAAATCTGGACTCCAGATACATTTTTCCACAATGGAAAGAAGTCTGTGGCCCACAACATGACCATG CCTAATAAGCTCCTGCGTATCACAGAGGATGGCACTCTGCTGTACACCATGAGGTTGACCGTGAGAGCTG AATGCCCAATGCACTTGGAAGACTTCCCTATGGATGCCCATGCCTGCCCACTAAAATTCGGAAGCTATGC TTATACAAGAGCAGAAGTTGTCTATGAGTGGACCAGAGAGCCAGCCCGTTCAGTGGTTGTAGCAGAAGAT GGGTCACGTTTAAACCAGTATGACCTTCTTGGACAAACAGTTGACTCTGGAATTGTTCAGTCCAGTACTG GAGAATATGTGGTTATGACGACTCACTTCCACTTGAAGAGAAAAATTGGCTACTTTGTTATTCAAACATA TCTGCCGTGCATAATGACAGTTATTCTCTCCCAAGTCTCCTTCTGGCTCAACAGAGAGTCAGTACCAGCA AGAACTGTCTTTGGAGTGACGACTGTTCTGACTATGACAACCTTGAGTATCAGTGCCAGAAATTCCCTCC CGAAGGTGGCTTATGCAACAGCTATGGACTGGTTTATTGCAGTATGCTATGCCTTTGTTTTCTCAGCTCT GATTGAGTTTGCCACAGTAAACTATTTCACCAAGAGAGGGTATGCGTGGGATGGCAAAAGCGTGGTTCCA GAAAAGCCAAAGAAAGTAAAGGATCCTCTCATTAAGAAAAACAACACATATGCTCCTACAGCAACCAGCT ATACCCCTAACTTAGCCAGGGGTGACCCCGGCTTGGCAACTATTGCTAAAAGTGCGACCATAGAACCGAA AGAAGTCAAGCCTGAGACAAAACCACCAGAACCCAAGAAAACCTTTAACAGCGTCAGCAAAATCGACCGA CTGTCAAGAATAGCCTTTCCGCTGCTATTTGGAATCTTTAACTTAGTCTATTGGGCCACGTATTTAAACA GAGAGCCTCAGCTAAAAGCCCCCACACCCCATCAATAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_010250 |
| Insert Size | 1368 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_010250.5, NP_034380.1 |
| RefSeq Size | 4702 bp |
| RefSeq ORF | 1368 bp |
| Locus ID | 14394 |
| UniProt ID | P62812 |
| Gene Summary | Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain (PubMed:27129275). Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel (PubMed:27129275). The gamma2 subunit is necessary but not sufficient for a rapid formation of active synaptic contacts and the synaptogenic effect of this subunit is influenced by the type of alpha and beta subunits present in the receptor pentamer (PubMed:27129275). The alpha1/beta2/gamma2 receptor and the alpha1/beta3/gamma2 receptor exhibit synaptogenic activity (PubMed:27129275). GABRA1-mediated plasticity in the orbitofrontal cortex regulates context-dependent action selection (PubMed:25348603). Functions also as histamine receptor and mediates cellular responses to histamine (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG227303 | Gabra1 (tGFP-tagged) - Mouse gamma-aminobutyric acid (GABA) A receptor subunit alpha 1 (Gabra1), (10ug) |
CNY 5,256.00 |
|
| MR227303 | Gabra1 (Myc-DDK-tagged) - Mouse gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 (Gabra1) |
CNY 3,656.00 |
|
| MR227303L3 | Lenti ORF clone of Gabra1 (Myc-DDK-tagged) - Mouse gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 (Gabra1) |
CNY 5,230.00 |
|
| MR227303L4 | Lenti ORF clone of Gabra1 (mGFP-tagged) - Mouse gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 (Gabra1) |
CNY 5,230.00 |
