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Gata4 (NM_008092) Mouse Untagged Clone
CAT＃: MC215787
Gata4 (untagged) - Mouse GATA binding protein 4 (Gata4), (10ug)
CNY 3,656.00
CNY 5,700.00
| Cited in 8 publications. |
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | Gata-4 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC215787 representing NM_008092
Red=Cloning site Blue=ORF TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTACCAAAGCCTGGCCATGGCCGCCAACCACGGCCCCCCGCCCGGCGCCTACGAAGCAGGTGGCCCTG GCGCCTTCATGCACAGCGCGGGCGCCGCGTCCTCGCCCGTCTACGTGCCCACTCCGCGGGTGCCGTCCTC TGTGCTGGGCCTGTCCTACCTGCAGGGCGGTGGCAGTGCCGCTGCAGCTGGAACCACCTCGGGTGGCAGC TCCGGGGCCGGCCCGTCGGGTGCGGGGCCTGGGACCCAGCAGGGTAGCCCTGGCTGGAGCCAAGCTGGAG CCGAGGGAGCCGCCTACACCCCGCCGCCCGTGTCCCCGCGCTTCTCTTTCCCGGGGACTACTGGGTCCCT GGCGGCCGCTGCCGCCGCTGCCGCAGCCCGGGAAGCTGCAGCCTACGGCAGTGGCGGCGGGGCGGCGGGC GCTGGTCTGGCTGGCCGAGAGCAGTACGGGCGTCCGGGCTTCGCCGGCTCCTACTCCAGCCCCTACCCAG CCTACATGGCCGACGTGGGAGCATCCTGGGCCGCAGCCGCTGCCGCCTCTGCCGGCCCCTTCGACAGCCC AGTCCTGCACAGCCTGCCTGGACGGGCCAACCCTGGAAGACACCCCAATCTCGATATGTTTGATGACTTC TCAGAAGGCAGAGAGTGTGTCAATTGTGGGGCCATGTCCACCCCACTCTGGAGGCGAGATGGGACGGGAC ACTACCTGTGCAATGCCTGTGGCCTCTATCACAAGATGAACGGCATCAACCGGCCCCTCATTAAGCCTCA GCGCCGCCTGTCCGCTTCCCGCCGGGTAGGCCTCTCCTGTGCCAACTGCCAGACTACCACCACCACGCTG TGGCGTCGTAATGCCGAGGGTGAGCCTGTATGTAATGCCTGCGGCCTCTACATGAAGCTCCATGGGGTTC CCAGGCCTCTTGCAATGCGGAAGGAGGGGATTCAAACCAGAAAACGGAAGCCCAAGAACCTGAATAAATC TAAGACGCCAGCAGGTCCTGCTGGTGAGACCCTCCCTCCCTCCAGTGGTGCCTCCAGCGGTAACTCCAGC AATGCCACTAGCAGCAGCAGCAGCAGTGAAGAGATGCGCCCCATCAAGACAGAGCCCGGGCTGTCATCTC ACTATGGGCACAGCAGCTCCATGTCCCAGACATTCAGT:ACTGTGTCCGGCCACGGGCCCTCCATCCATC CAGTGCTGTCTGCTCTGAAGCTGTCCCCACAAGGCTATGCATCTCCTGTCACTCAGACATCGCAGGCCAG CTCCAAGCAGGACTCTTGGAACAGCCTGGTCCTGGCTGACAGTCATGGGGACATAATCACCGCGTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_008092 |
| Insert Size | 1326 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC137824, AAI37825 |
| RefSeq Size | 2299 bp |
| RefSeq ORF | 1326 bp |
| Locus ID | 14463 |
| UniProt ID | Q08369 |
| Gene Summary | Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development (By similarity). In cooperation with TBX5, it binds to cardiac super-enhancers and promotes cardiomyocyte gene expression, while it downregulates endocardial and endothelial gene expression (By similarity). Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression (By similarity). Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions (By similarity). Acts as a transcriptional activator of ANF in cooperation with NKX2-5 (PubMed:9584153). Promotes cardiac myocyte enlargement (By similarity). Required during testicular development (By similarity). May play a role in sphingolipid signaling by regulating the expression of sphingosine-1-phosphate degrading enzyme, spingosine-1-phosphate lyase (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) uses an alternate in-frame donor splice site in the central coding region compared to variant 1. The encoded isoform (2) is one amino acid shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (8)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
p63 silencing induces epigenetic modulation to enhance human cardiac fibroblast to cardiomyocyte-like differentiation
,null,
Scientific Reports
,PubMed ID 35794145
[Gata4]
|
|
Variants in a cis -regulatory element of TBX1 in conotruncal heart defect patients impair GATA6-mediated transactivation
,null,
Orphanet Journal of Rare Diseases
,PubMed ID 34332615
[Gata4]
|
|
Analysis of variants in GATA4 and FOG2 / ZFPM2 demonstrates benign contribution to 46,XY disorders of sex development
,null,
Molecular Genetics & Genomic Medicine
,PubMed ID 31962012
[Gata4]
|
|
The Use of Foxa2-Overexpressing Adipose Tissue-Derived Stem Cells in a Scaffold System Attenuates Acute Liver Injury
,null,
Gut and Liver
,PubMed ID 30602218
[Gata4]
|
|
Direct Reprogramming of Human Fibroblasts to Hepatocyte-Like Cells by Synthetic Modified mRNAs
,null,
PLoS ONE
,PubMed ID 24963715
[Gata4]
|
|
EVOLUTIONARY CONSERVATION OF GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE (GIP) GENE REGULATION AND THE ENTEROINSULAR AXIS
,null,
,PubMed ID 20621665
[Gata4]
|
|
Heterogeneous sphingosine-1-phosphate lyase gene expression and its regulatory mechanism in human lung cancer cell lines.
,null,
Biochimica et biophysica acta
,PubMed ID 21184844
[Gata4]
|
|
WNT4 is expressed in human fetal and adult ovaries and its signaling contributes to ovarian cell survival.
,null,
Molecular and cellular endocrinology
,PubMed ID 19962424
[Gata4]
|
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG227022 | Gata4 (tGFP-tagged) - Mouse GATA binding protein 4 (Gata4), (10ug) |
CNY 5,256.00 |
|
| MR227022 | Gata4 (Myc-DDK-tagged) - Mouse GATA binding protein 4 (Gata4) |
CNY 3,656.00 |
|
| MR227022L3 | Lenti ORF clone of Gata4 (Myc-DDK-tagged) - Mouse GATA binding protein 4 (Gata4) |
CNY 6,056.00 |
|
| MR227022L4 | Lenti ORF clone of Gata4 (mGFP-tagged) - Mouse GATA binding protein 4 (Gata4) |
CNY 6,056.00 |
