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Crhr2 (NM_009953) Mouse Untagged Clone
CAT＃: MC208334
Crhr2 (untagged) - Mouse corticotropin releasing hormone receptor 2 (Crhr2), (10ug)
CNY 5,488.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | CRF-R2; Crfr2; CRFR2alpha; CRFR2beta |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_009953 |
| Insert Size | 1293 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_009953.4, NP_034083.2 |
| RefSeq Size | 2697 bp |
| RefSeq ORF | 1293 bp |
| Locus ID | 12922 |
| Gene Summary | G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) uses an alternate splice junction at the 5' end of an exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but lacks an alternate internal aa compared to isoform 1. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Opposing roles of the entero-pancreatic hormone urocortin-3 in glucose metabolism in rats
,null,
Diabetologia
,PubMed ID 35325259
[Crhr2]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG226210 | Crhr2 (tGFP-tagged) - Mouse corticotropin releasing hormone receptor 2 (Crhr2), (10ug) |
CNY 4,750.00 |
|
| MR226210 | Crhr2 (Myc-DDK-tagged) - Mouse corticotropin releasing hormone receptor 2 (Crhr2) |
CNY 5,488.00 |
|
| MR226210L3 | Lenti ORF clone of Crhr2 (Myc-DDK-tagged) - Mouse corticotropin releasing hormone receptor 2 (Crhr2) |
CNY 6,180.00 |
|
| MR226210L4 | Lenti ORF clone of Crhr2 (mGFP-tagged) - Mouse corticotropin releasing hormone receptor 2 (Crhr2) |
CNY 7,888.00 |
