United States
Germany
Japan
United Kingdom
China
Ldlrap1 (NM_145554) Mouse Untagged Clone
CAT＃: MC207795
Ldlrap1 (untagged) - Mouse low density lipoprotein receptor adaptor protein 1 (Ldlrap1), (10ug)
CNY 3,990.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AA691260; Arh; Arh1; ARH2; FHCB1; FHCB2 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC207795 representing NM_145554
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGACGCGCTCAAGTCGGCGGGGCGCGCGCTAATCCGGAGCCCCAGTCTGGCCAAGCAGAGCTGGGCGG GCGGCCGGCACCGCAAGTTGCCAGAGAACTGGACGGACACGCGGGAGACACTGCTGGAGGGCATGGTTTT CAGCCTCAAGTACCTTGGTATGACGCTGGTGGAGCGGCCCAAGGGCGAGGAGCTGTCTGCAGCTGCTGTC AAGAGGATCGTAGCTACAGCCAAGGCCAGCGGGAAGAAGCTGCAGAAGGTGACACTCAAGGTGTCACCCC GGGGGATCATCCTGACCGACAGCCTCACTAGCCAGCTCATCGAGAACGTGTCCATTTACAGGATCTCCTA CTGCACTGCAGACAAGATGCACGACAAGGTGTTCGCCTACATCGCCCAGAGCCAGCAGAACGAGAGCCTC GAGTGCCACGCCTTCCTCTGCACCAAGCGGAAAGTGGCCCAAGCCGTCACCCTGACTGTAGCCCAAGCCT TCAAAGTTGCCTTTGAGTTTTGGCAGGTGTCCAAGGAAGAGAAAGAGAAAAGGGAGAAAGCCAACCAGGA AGGAGGAGACGTCCCAGGGACCCGACGGGACAGCACCCCCTCACTGAAAACCTTGGTCGCTACCGGGAAC CTGCTGGATTTGGAAGAGGTGGCTAAGGCCCCGTTATCTACAGTCAGCGCTAATACCAACAACGTGGACG AGACACCACGGCCTCAGGTCTTGGGCAACAACAGCGTCGTCTGGGAGCTGGATGACGGCCTGGACGAAGC ATTTTCAAGGCTGGCGCAGTCCCGGACAAACCCTCAAGTCCTGGACACTGGACTGTCAGCACAGGACATC CATTATGCACAGTGCTTATCGCCCACCGACTGGGACAAGCCTGACAGCAGTGGCATTGATCAAGATGATG ACGTCTTCACCTTCTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_145554 |
| Insert Size | 927 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_145554.2, NP_663529.2 |
| RefSeq Size | 2671 bp |
| RefSeq ORF | 927 bp |
| Locus ID | 100017 |
| UniProt ID | Q8C142 |
| Gene Summary | Adapter protein (clathrin-associated sorting protein (CLASP)) required for efficient endocytosis of the LDL receptor (LDLR) in polarized cells such as hepatocytes and lymphocytes, but not in non-polarized cells (fibroblasts). May be required for LDL binding and internalization but not for receptor clustering in coated pits. May facilitate the endocytocis of LDLR and LDLR-LDL complexes from coated pits by stabilizing the interaction between the receptor and the structural components of the pits. May also be involved in the internalization of other LDLR family members. Binds to phosphoinositides, which regulate clathrin bud assembly at the cell surface. Required for trafficking of LRP2 to the endocytic recycling compartment which is necessary for LRP2 proteolysis, releasing a tail fragment which translocates to the nucleus and mediates transcriptional repression (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG203503 | Ldlrap1 (tGFP-tagged) - Mouse low density lipoprotein receptor adaptor protein 1 (Ldlrap1) |
CNY 2,850.00 |
|
| MR203503 | Ldlrap1 (Myc-DDK-tagged) - Mouse low density lipoprotein receptor adaptor protein 1 (Ldlrap1) |
CNY 2,400.00 |
|
| MR203503L3 | Lenti ORF clone of Ldlrap1 (Myc-DDK-tagged) - Mouse low density lipoprotein receptor adaptor protein 1 (Ldlrap1) |
CNY 4,750.00 |
|
| MR203503L4 | Lenti ORF clone of Ldlrap1 (mGFP-tagged) - Mouse low density lipoprotein receptor adaptor protein 1 (Ldlrap1) |
CNY 4,750.00 |
其它Ldlrap1产品
