Prc1 (BC005475) Mouse Untagged Clone
CAT#: MC206793
Prc1 (untagged) - Mouse protein regulator of cytokinesis 1 (cDNA clone MGC:6745 IMAGE:3592138), (10ug)
CNY 4,496.00
货期*
现货
规格
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经常一起买 (3)
Specifications
Product Data | |
Type | Mouse Untagged Clone |
Tag | Tag Free |
Synonyms | MGC6745 |
Vector | PCMV6-Kan/Neo |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>BC005475
CCGTTCTCCGTCCCGCGCGTGGCAAGTGGAGGGTCTCGATTCTGGACAGCTTGGAGCGTCCACCATGAGG AGAAGTGAGGTGCTAGCAGATGAGTCTATCACATGCCTGCAGAAAGCTCTAACTCACCTCCGGGAAATAT GGGAACTAATTGGGATTCCAGAGGAGCAGAGGCTACAAAGAACCGAGGTTGTAAAGAAGCATATAAAGGA TCTTCTGGATAGAATGATTGCTGAAGAGGAGAGCCTGAGGGAAAGGCTGCTTAAAAGCATATCCATCTGT CAGAAGGAGCTGAGTACCCTGTGCAGTGAGCTACAAGTGAAGCCATTTCAGGAAGAAAAAGATACAACCA TCTTGCAACTAGAAAAAGATCTGCGCACTCAAGTAGAATTGATGAGAAAACAGAAAAAGGAGAGAAAGCA GGAATTGAAGCTACTTCAGGAACAGGAGCAAGAACTCCGTGACATCCTCTGTATGCCGCCCTGTGATGTG GACAGCACCTCTGTCCCCACCTTAGAAGAGCTGAAGCTATTCCGACAGCGTGTGGCAACGCTGAGGGAGA CAAAGGAATCGAGGCGTGAAGAATTTGTCAACATTAAGAAACAAATCATATTGTGTATGGAAGAATTAGA ACACTCTCCAGATACAAGCTTTGAAAGAGATGTGGTGTGTGAAGATGAAAGTGCTTTTTGTTTATCACTG GAGAACATTGCAACATTACAGAAGTTGCTGAAGCAGCTGGAAATGAAAAAATCACAAAATGAAGCAGAAT GTGAGGGGCTTCGCACTCAAATCCGAGAGCTCTGGGATAGGTTACAAATACCTGAAGAAGAGAGAGAGCC TGTGGAGGCAATTATGACTGGATCAAAAACCAAAATCAGGAATGCGCTGAAATTAGAAGTGGATCGGTTA GAAGAACTGAAAATGCAAAACATAAAGCAAGTGATTGAGAAAATCCGAGTGGAGCTGGCTCAGTTCTGGG ACCAGTGTTTTTATAGCCAGGAACAGAGGCAGGCTTTTGCCCCTTACTATTCTGAGGACTACACAGAAAA CCTGCTCCATCTTCATGATGCCGAGATTGTACGGTTAAGAAACTACTATGACGCTCACAAGGAGCTGTTC CAAGGCGTCCAGAAGTGGGAAGAGAGCTGGAAACTTTTCCTAGAGTTTGAGAGAAAAGCTTCAGATCCAG GTCGGTTTACAAACCGAGGGGGAAATCTTTTAAAAGAAGAAAAGGAACGAGCAAAGCTCCAGAAAACACT CCCTAAGCTGGAAGAGGAGTTGAAAGCACGGATTGAACAGTGGGAACAGGAGCACTCAACAGCATTTGTG GTGAATGGGCAGAAATTCATGGAGTATGTTACAGAACAGTGGGAATTACATCGGCTGGAGAAAGAGCGAG CCAAACAGGAGAGGCAACTGAAGAACAAGAAACAGACAGAGGCAGAGATGCTGTATGGCAGTACTCCCCG GACACCTAGCAAAAGACCAGGACAGACGCCCAAGAAGTCTGGCAAAATGAACACTACCACCATGTCTAGT GCTACACCCAACAGTAGCATTCGGCCTGTCTTTGGTGGATCAGTGTACCGGTCACCTATGTCTCGACTAC CCCCTTCTGGCAGCAAGTCAGTTGTCACTTCTCTGTGTTCTGGAAAGAAAACACCTCGAGCTGCCCAGCT TAGGGCCAACAAGGAGAACTTGGACCTCAATGGCAGCATCCTGAGCGGTGGGTACCCTGGCTCGACGCCC CTCCAGCACAACTGCAGCATTAAGTCTGTTGCCAGCACCTATTCTGAGTTTTCGCGAGAACTTTCAAAGG CTTCCAGATCTGATGCTACGTCTCGAATCCTCAATTCAACCAACATCCAGTCCTGAGAGTCCTTGTCCAG TTAGGCAGCTGGGGCTTCCTGTGCCTGGACTGGACTGACGGATACGTAGACAAGGAGTGACGTATACATT TCCATCAGTTTAGATGTTTGAAACTACCTTGGGCAGGTTCTGTTAACTGCACCTAACTCAGACATGAGTA GGACAGAAGGAAGCTGTCCCGGGCGGACTGAGGTCACAAAGACTTGCTTTTGATTCAAGAGAGACCTTAA AGGCTAGTTATGATAGTTAAGTACAAGTTTTAACATCTGGTAGCTAATTTTTTTCTCTACCCCATAATTC TACTTTGACTGCTCTTCTAGAGGTCCTGAGTTCAAATCCCAGCAACCACATGGTGGCTCACAACCATCTA TAATGGGATCTGATGTCCTCTTCTGGTGTGCAGAAATAATTTTTTTTTAATTCTACTTATTTCAATACTA TATATTAGAAAATGAAAAAACGATTGTGGCCAGCTTTGGCATACAGGGGTACAAGACATGAAGTAATTCT GGTAACATCTAAAAATATATATATTTTTGTTCGCGGACATTTGATTAATGCTGTAGCTATGGAAGCTTTG ATGTCACCCAGAGGCGTGTACCTGGCTGGCACTATCCCAGTGAGGGTTTCTTGAGTTCCAGTATGAGATG GCCTGACCTGCTGCCAAAAAGAGTAGCAGTCATTTCTGTAGTGCAATTTCTTGAGGTATATGTGTGAACA CACATGCTTGTCTGACCTGTTGAGTTTTTCTCCAGTCTCCCAACCCTGTGCTCATTAGGCCCAGTCTGTT CCCTGTAGATGACAACCACATAGAGAGGCTGTCTGGTGGGCTGGGCCATTCCTGTCATGGAGTCAGCAAC TTTGCACATCTACAAGTTATCTGTGTAATCACGTCCACAATGAGGCTCTCCAAACCCATCACTACTCTTC CCCAAAGCACTATATTTATTCTGTCTGTCTGTGCCAGTTCTGCCCACACTGACTGATCTTGAAAACTTGT CAGTCTGCTCTTCACACACACATATATATATGTTGTTTTTAAATGTATGAAAATAAAATGTGTATAGTTA CCTTTTAAATACTAAAAAAAAAAAAAAAAAAAAAAAAA |
Restriction Sites | EcoRI-NotI |
ACCN | BC005475 |
Insert Size | 1812 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | BC005475, AAH05475 |
RefSeq Size | 2978 bp |
RefSeq ORF | 1812 bp |
Locus ID | 233406 |
Gene Summary | Key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. Essential for controlling the spatiotemporal formation of the midzone and successful cytokinesis. Required for KIF14 localization to the central spindle and midbody. Required to recruit PLK1 to the spindle. Stimulates PLK1 phosphorylation of RACGAP1 to allow recruitment of ECT2 to the central spindle. Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression.[UniProtKB/Swiss-Prot Function] |
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