Cyp2e1 (BC013451) Mouse Untagged Clone
CAT#: MC206516
Cyp2e1 (untagged) - Mouse cytochrome P450, family 2, subfamily e, polypeptide 1 (cDNA clone MGC:18528 IMAGE:4223797), (10ug)
CNY 3,656.00
货期*
现货
规格
Cited in 3 publications. |
Product images
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经常一起买 (3)
Specifications
Product Data | |
Type | Mouse Untagged Clone |
Tag | Tag Free |
Synonyms | Cyp2e |
Vector | PCMV6-Kan/Neo |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>BC013451
GTGGAGCCCCATCGGCACCATGGCGGTTCTTGGCATCACCGTTGCCTTGCTTGTCTGGATCGCCACCCTC CTCCTCGTATCCATCTGGAAACAGATCTATAGAAGTTGGAACCTGCCCCCAGGACCTTTCCCAATTCCTT TCTTTGGAAACATTTTTCAGCTGGATTTGAAGGATATTCCCAAGTCTTTAACCAAGTTGGCAAAGCGCTT CGGGCCAGTGTTCACACTGCACCTGGGTCAGAGGCGCATCGTGGTCCTGCATGGCTACAAGGCTGTCAAG GAGGTGCTACTGAACCACAAGAATGAGTTCTCTGGCCGAGGGGACATTCCTGTGTTCCAGGAGTACAAGA ACAAGGGGATTATTTTCAATAATGGACCCACATGGAAGGACGTGCGGAGGTTTTCCCTAAGTATCCTCCG TGACTGGGGAATGGGGAAACAGGGTAATGAGGCCCGCATCCAAAGAGAGGCACACTTCCTGGTGGAGGAG CTCAAAAAGACCAAAGGCCAGCCTTTTGACCCTACCTTTCTGATTGGCTGTGCACCCTGCAATGTCATTG CGGATATTCTCTTCAACAAACGCTTCGATTACGATGACAAGAAGTGTCTGGAGCTCATGAGTTTGTTCAA TGAAAACTTCTACCTGCTGAGTACTCCCTGGATCCAGGCTTACAATTACTTTTCGGATTATCTACAATAT CTACCTGGAAGCCACAGAAAAGTCATGAAAAATGTGTCTGAAATAAGACAGTACACACTTGGAAAAGCCA AGGAACACCTTAAGTCACTGGACATCAACTGCCCCCGGGATGTGACTGACTGTCTCCTCATAGAGATGGA GAAGGAAAAACACAGCCAAGAACCCATGTACACAATGGAAAATATTTCTGTGACTTTGGCCGACCTGTTC TTTGCAGGAACAGAGACCACCAGCACAACTCTGAGATATGGGCTCCTGATTCTCATGAAATACCCAGAAA TTGAAGAGAAACTTCATGAAGAAATTGACAGGGTTATTGGGCCAAGCCGTGCCCCTGCAGTCCGAGACAG GATGAATATGCCCTACATGGACGCTGTAGTGCATGAGATTCAGAGATTCATCAACCTCGTCCCTTCCAAC CTGCCCCACGAAGCAACCCGAGACACCGTGTTCCGAGGATATGTCATCCCCAAGGGTACAGTTGTAATTC CAACTCTGGACTCCCTTTTATTTGACAACTATGAGTTTCCAGATCCAGAGACATTTAAACCTGAGCATTT TCTGAATGAAAATGGGAAGTTCAAGTACAGTGACTATTTCAAGGCGTTTTCTGCAGGAAAGCGCGTGTGT GTTGGAGAAGGCCTGGCCCGCATGGAACTGTTTCTGCTTTTGTCTGCTATTCTGCAGCATTTTAATCTGA AGTCTCTGGTTGACCCTAAGGATATCGACCTCAGCCCTGTTACAATTGGCTTTGGCAGTATCCCACGCGA ATTTAAACTCTGTGTCATTCCTCGTTCATGAGACCTGCTGCCCATCATTATCCCTTACAAAATGACTGTT TAAAAAAATGCCAAGCGGGCTGGTGAGATGGCTCAGTGGGTAAGAGCACCCGACTGCTCTTCCGAAGGTC CGGAGTTCAAATCCCAGCAACCACATGGTGGCTCACAACCATCTGTATCGAGATCTGACTCTGTCTTCTG GAGTGTCTGAAGACAGCTACAGTGTACTTACATATAATAAATAAATAAGTCTTTAAAAAAAAAAAAAAAA AAAAAAAAA |
Restriction Sites | EcoRI-NotI |
ACCN | BC013451 |
Insert Size | 1482 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | BC013451, AAH13451 |
RefSeq Size | 1759 bp |
RefSeq ORF | 1482 bp |
Locus ID | 13106 |
Gene Summary | A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics.[UniProtKB/Swiss-Prot Function] |
Citations (3)
The use of this cDNA Clones has been cited in the following citations: |
---|
Relative Contributions of CYP1A2 and CYP2E1 to the Bioactivation and Clearance of 4-Aminobiphenyl in Adult Mice.
,null,
Drug metabolism and disposition: the biological fate of chemicals
,PubMed ID 25922528
[Cyp2e1]
|
N -Hydroxylation of 4-Aminobiphenyl by CYP2E1 Produces Oxidative Stress in a Mouse Model of Chemically Induced Liver Cancer
,null,
Toxicological Sciences
,PubMed ID 25601990
[Cyp2e1]
|
Mechanisms of 4-aminobiphenyl-induced Liver Carcinogenesis in the Mouse
,Wang, S;,
Thesis
[CYP2E1]
|
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