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Gba2 (NM_172692) Mouse Untagged Clone
CAT＃: MC205278
Gba2 (untagged) - Mouse glucosidase beta 2 (Gba2), (10ug)
CNY 2,000.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | F630034E04 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC056935
CGAGGCCACCGGGGTCGTGAGGACCCAGGATCCAGTGAACATGGTAACCTGCGTCCCGGCCTCAGAGCAG GTCGGCTGTGCCGAAAGAGATTCCCAAGTTTATTGTGAAGATACTGGCGGCACTGAGGCTGTGCGGGTTA CAGACTGCGGGAGCCCCGAGGATAGTGGACCCCAGGATGAACCAAGCTACTGCAATTCAGAGGACTCTGG GCAGCTGATGGCCTCCTACGAGGGTAAAGCTAGGGGCTACCAGGTGCCTCCTTTTGGCTGGCGGATCTGC TTGGCTCACGAGTTTGCAGAGAAGAGGAGACCTTTTCAAGCTAACAACATCTCTCTCAGTAATTTGGTAA AGCACCTCGGTATGGGCTTGAGGTACTTGAAGTGGTGGTACCGAAAGACCCACGTGGAAAAGAAGACCCC TTTCATCGACATGCTCAATTCTCTACCCCTGAGACAGATCTATGGTTGTCCCCTGGGTGGCATTGGAGGA GGCACTATCACCCGGGGCTGGAGAGGCCAGTTCTGTCGTTGGCAGCTCAACCCTGGAATGTACCAGCACC AGACAGTCATTGCAGACCAATTTATAGTATGCTTGCGTCGAGATGGGCGGACTGTGTACCAGCAAGTTCT GTCCTTGGAGCTTCCAAATGTCCTGCGCAGCTGGAACTGGGGCCTGTGTGGTTACTTTGCTTTCTACCAC GCCCTCTATCCCCGAGCCTGGACGGTCTATCAGCTTCCTGGCCAGAATGTCACCCTCACCTGTCGCCAGG TCACACCTATCTTGCCTCATGACTACCAGGACAGCAGTCTCCCTGTAGGAGTCTTTGTGTGGGATGTAGA AAACGAAGGAGATGAGACTCTGGACGTTTCCATCACGTTCTCCATGCGGAATGGACTAGGAGGCGAAGAT GATGCGGCCGGGAGTTTGTGGAATGAGCCCTTCCGCCTGGAACAGGGCGGGACGACTGTTCAGGGGCTCC TCTTGCATCATCCAACCCCTCCGAACCCCTACACCATGGCTGTGGCTGCACGATGCACGGCAGATACCAC GGTAACCCACACCACAGCCTTTGACCCCAATGGCACTGGACAGCAGGTGTGGCAGGACCTACTTCAGGAT GGACAGCTGGACTCCCCTGCTGGCCAAAGCACCCCAACACAGAAAGGAGAGGGTATCGCTGGGGCTGTAT GCGTCTCTAGCAAGCTGTTACCTCGAAGCCGGTGCTGCTTGGAGTTCTCACTGGCTTGGGATATGCCTAA GATCATGTTTGGAGCTAAAAGCCAAGTCCACTACAGGCGGTATACACGGTTCTTTGGTTCAGATGGTGAT GTGGCGCCTGCCCTGAGCCACTATGCACTGTGCCACTATGCAGACTGGGAGGACAGAATCTCAGCCTGGC AGAACCCAGTACTGGATGACAGAACCTTGCCTGCCTGGTACAAATCTGCACTGTTCAATGAACTGTACTT CCTGGCCGATGGAGGCACAGTGTGGCTGGAAGTTCCCGCAGACTCCCTACCAGAGGGGCTGGGAGGGAGT ATGCGTCAGCTTCGCTCTACTCTGCAGGACTATGGGCGATTTGGCTATCTTGAAGGCCAGGAGTACCGCA TGTACAACACATACGATGTCCACTTTTATGCGTCCTTTGCCCTCGTCATGCTGTGGCCCAAACTTGAGCT CAGTCTTCAGTATGATATGGCTCTGGCAACTTTGAAGGAGGACCTGACCCGGCGACGGTACCTGATGAGT GGAGTGGTGGCACCTGTGAAAAGGAGGAACGTCATCCCTCATGACATTGGGGATCCGGATGATGAGCCAT GGCTCCGGGTCAACGCATATTTGATTCATGATACTGCTGACTGGAAGGACCTGAACCTGAAGTTTGTATT GCAAATTTATCGGGACTATTACCTGACGGGTGATCAAGGCTTCCTGGAGGACATGTGGCCTGTGTGTCTG GCTGTGATGGAGTCCGAAATGAAGTTTGACAAGGACCAAGATGGACTCATTGAGAATGGAGGCTACGCAG ACCAGACCTATGATGCATGGGTCACCACAGGCCCCAGTGCTTACTGCGGAGGGCTGTGGCTGGCGGCAGT GGCTGTAATGGTTCAGATGGCTGTTCTGTGTGGGGCCCAAGATGTCCAGGAGAGGTTTGCTTCCATTCTC TGCCGAGGCCGAGAAGCTTATGAGAGACTGCTGTGGAACGGACGCTATTACAACTACGACAGCAGCTCCC ATCCTCAGTCTCGGAGCATCATGTCTGACCAGTGTGCTGGGCAGTGGTTCCTGAGGGCCTGCGGCCTGGG AGAAGGAGACACTGAAGTATTTCCTACCCTGCATGTGGTCCGTGCTCTCCAAACCATCTTTGAACTCAAC GTCCAAGCCTTTGCAGGAGGAGCCATGGGGGCCGTGAACGGGATGCACCCTCATGGTGTCCCTGATAGAT CCAGTGTGCAGTCTGATGAAGTCTGGGTGGGTGTGGTCTATGGGCTGGCAGCCACCATGATCCAAGAGGG CCTGACTTGGGAAGGTTTCCGGACAGCTGAAGGCTGTTACCGCACTGTATGGGAACGCCTGGGCCTGGCT TTCCAGACCCCAGAGGCATACTGCCAGCAACAAGTGTTCCGCTCCCTGGCCTACATGCGGCCACTGAGCA TCTGGGCCATGCAGCTGGCCCTGCAACAGCAGCAGCATAAAAAGAGCCGCAGGCCATCAGTCACACAAGG CACGGGACTAAGCACACAGCCTGAATGTGGACCAAAGAGATCGCTGGCAAACCTCAATTCAGAGTGATCC CTCTGAACTGTGGAGGCCCAGCCTCCACACTGGACCTCCTCCTTCCTCCCACAAGTCCTGCAGCCCTGAG CCAATAGGACAATCGCGCCCCTCTTCCTTCCCAGCTGTGCCAGTAAAAAGGGGCTGAGGAACCACTTATT TATTTCTTACCCTACCCAGTCCTTCCATGGATGAAGTATTCAAGGCCAGTAAATGTCTCCAAATCTATTC ACGGGGCAACAGATACATATGGGTATAAATAAAATACTCAGAAAACTAAAAAAAAAAAAAAAAAA |
| Restriction Sites | AscI-NotI |
| ACCN | NM_172692 |
| Insert Size | 2757 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | BC056935, AAH56935 |
| RefSeq Size | 3075 bp |
| RefSeq ORF | 2757 bp |
| Locus ID | 230101 |
| UniProt ID | Q69ZF3 |
| Gene Summary | Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide (PubMed:17080196, PubMed:23250757). Glucosylceramides are membrane glycosphingolipids that have a wide intracellular distribution (PubMed:23250757). They are the main precursors of more complex glycosphingolipids that play a role in cellular growth, differentiation, adhesion, signaling, cytoskeletal dynamics and membrane properties (PubMed:25803043). Also involved in the transglucosylation of cholesterol, transferring glucose from glucosylceramides, thereby modifying its water solubility and biological properties (PubMed:26724485). Under specific conditions, may catalyze the reverse reaction, transferring glucose from cholesteryl-beta-D-glucoside to ceramide (PubMed:26724485). Finally, may also play a role in the metabolism of bile acids (PubMed:17080196). It is able to hydrolyze bile acid 3-O-glucosides but also to produce bile acid-glucose conjugates thanks to a bile acid glucosyl transferase activity (PubMed:17080196). However, the relevance of both activities is unclear in vivo (PubMed:17080196).[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG211175 | Gba2 (tGFP-tagged) - Mouse glucosidase beta 2 (Gba2) |
CNY 8,930.00 |
|
| MR211175 | Gba2 (Myc-DDK-tagged) - Mouse glucosidase beta 2 (Gba2) |
CNY 6,720.00 |
|
| MR211175L3 | Lenti ORF clone of Gba2 (Myc-DDK-tagged) - Mouse glucosidase beta 2 (Gba2) |
CNY 9,980.00 |
|
| MR211175L4 | Lenti ORF clone of Gba2 (mGFP-tagged) - Mouse glucosidase beta 2 (Gba2) |
CNY 9,980.00 |
