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Stra6 (NM_009291) Mouse Untagged Clone
CAT＃: MC205249
Stra6 (untagged) - Mouse stimulated by retinoic acid gene 6 (Stra6), transcript variant 2, (10ug)
CNY 4,912.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AI891933 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC075657
CTGGACTCAGTACAATTCATCAGGCGATACCCCCCTGGGAGTGATGGATAGTGACAAATGAGGGAAGAAG AGCTGGAGCATGGAGTCCCAGGCATCTGAGAATGGAAGCCAGACCTCCTCCGGGGTGACAGATGACTACA GCAGCTGGTACATCGAGGAACCTCTAGGAGCTGAGGAGGTGCAGCCAGAGGGGGTGATTCCCCTTTGCCA GCTCACCGCACCCCCTGCCCTGCTCCATGCCTGCCTGGCTTCACTGTCGTTCCTGGTTCTGCTGCTGCTG GCCTTGCTGGTGAGACGGCGCAGGCTTTGGCCACGCTGTGGTCATCGCGGACTTGGACTGCCCAGCCCTG TGGATTTCTTGGCTGGGGACCTATCCTGGACAGTGCCTGCTGCTGTCTTTGTGGTCCTCTTCAGCAACCT ATGCCTGTTGCTCCCTGATGAGAACCCACTGCCTTTCCTGAACCTCACTGCAGCATCAAGTCCAGATGGA GAGATGGAGACATCAAGAGGGCCCTGGAAGCTACTGGCTCTGCTCTACTATCCAGCCCTCTATTACCCTC TGGCTGCTTGTGCTTCGGCAGGGCACCAAGCTGCATTCCTATTGGGTACTGTGTTATCTTGGGCCCACTT TGGTGTTCAGGTCTGGCAGAAAGCTGAGTGTCCTCAGGATCCTAAGATCTACAAGCACTACTCCTTGCTG GCCTCCCTGCCTCTACTTCTGGGTCTTGGATTCCTGAGCCTTTGGTATCCAGTACAACTTGTGCAGAGTC TCCGTCACCCGACAGGAGCAGGCTCCCAGGGGCTGCAGACCAGCTACTCCGAGAAGTATCTGAGAACTCT TCTCTGCCCAAAGAAGTTGGATAGCTGCTCCCATCCTGCCTCCAAGCGTAGCCTCCTGTCTCGGGCCTGG GCCTTCTCCCATCATTCCATCTACACTCCACAGCCAGGATTCCGCCTGCCCTTGAAGCTGGTGATCTCGG CCACCCTGACAGGAACAGCCACTTACCAGGTGGCCCTGCTGCTGCTGGTGAGCGTGGTGCCTACTGTGCA GAAGGTGAGGGCGGGGATCAACACAGATGTCTCCTACCTGCTGGCTGGCTTTGGGATCGTGCTCTCTGAA GACAGGCAGGAGGTGGTAGAGCTGGTGAAGCATCACCTATGGACTGTGGAAGCATGCTACATCTCAGCTC TGGTCTTGTCCTGCGCATCAACCTTCCTGCTCCTGATCCGATCCCTGAGGACACACAGGGCCAATCTTCA AGCACTACACCGAGGGGCTGCCCTGGATCTGGACCCCCCTCTTCAGAGTATTCATCCCTCTCGCCAAGCC ATAGTCAGCTGGATGAGCTTCTGTGCCTACCAGACGGCCTTCAGCTGCCTTGGGCTCCTGGTGCAGCAGG TCATCTTCTTCTTGGGGACCACATCCCTGGCCTTCCTGGTGTTTGTGCCTTTACTGCATGGCAGGAACCT CCTGCTGCTGCGATCCCTGGAATCCACGTGGCCCTTCTGGCTGACTGTGGCCTTAGCTGTAATCCTGCAG AACATAGCAGCCAACTGGATCTTCCTGAGGACTCACCATGGATACCCAGAGCTGACCAACCGGCGCATGC TCTGCGTAGCTACTTTTCTCCTCTTCCCCATCAACATGCTGGTGGGAGCCATAATGGCTGTCTGGCGGGT GCTCATCTCTTCTCTCTACAACACTGTTCACCTCGGCCAGATGGACCTCAGCCTGCTGCCGCAGAGGGCA GCCTCCCTGGATCCAGGCTACCACACATACCAAAACTTCCTGAGGATTGAGGCCAGCCAGTCACATCCAG GAGTCATAGCCTTCTGTGCCCTGCTCCTCCATGCTCCAAGTCCACAGCCCCGGCCCCCATTGGCCCCTCA GGACAGCCTCAGGCCGGCAGAAGAAGAAGAAGGGATGCAGTTGCTACAGACCAAGGACCTGATGGCCAAG GGAGCAGGACACAAAGGCAGCCAGAGCAGGGCCCGCTGGGGTCTGGCCTACACATTGCTCCACAATCCAA GCCTACAGGCCTTCCGGAAGGCAGCCCTTACTAGTGCCAAGGCCAATGGCACCCAGCCCTGAGGGTGAAG AAAACCACATCACCCTGCCTTTATGTGCTGAGGCACATTCCTGTCTCCCATCCTCCCTCCCATTCATGTC TGCAACCCCCTCGCCCCAGCAGCAGCTCTGCCAGCCAGCTGATCCCTGTGGGATCAGGGGACTGGAGTCA CTGTGTCTACACCACCAGCTTCTAGAGGAATTTGGTCTATGCTTGTCCACCAGGCTACCAGCTAGGGCTC TAGAGAAAGCAGCTAGTGGTTTCTTTGTCTTGGAACAGGCAGGGTAAGGGTGGGCACATTTAGGCCTCTT CTCCTCACACTGGCCCTGCCATCAGCTTTTGGGGCCTCAGCAAGGCCTCTCTTTCTCCCCGTTGGTGATG AAAGGCCTGAATATCTCCCATCCCAGCTGGCCCCACCTCAGCCCCAGCCCTCCCACCATGAAAGTGGAAC CTGTGTGGGCTTCCTCTCTGCCCCAGATCTCTCCTTCCTCTCTCTTCCTTCCACTCCCGCCCCTTCTCTT GCAGCCAAGTCAGACTCCAAGAGGCCCCACTGAGCTGCCCTCTCCAAAAACCAGATTTTTTTTTGTAGTT TTAATGCCATTAGTTGTCATGAAAGAAGTTAGTGTGCTCTCTGTAATAAATGTGCCTCTGAGGAAAAAAA AAAAAAAAAAAAA |
| Restriction Sites | AscI-NotI |
| ACCN | NM_009291 |
| Insert Size | 2013 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC075657, AAH75657 |
| RefSeq Size | 2743 bp |
| RefSeq ORF | 2013 bp |
| Locus ID | 20897 |
| UniProt ID | O70491 |
| Gene Summary | Functions as retinol transporter (PubMed:23839944, PubMed:24852372). Accepts all-trans retinol from the extracellular retinol-binding protein RBP4, facilitates retinol transport across the cell membrane, and then transfers retinol to the cytoplasmic retinol-binding protein RBP1. Retinol uptake is enhanced by LRAT, an enzyme that converts retinol to all-trans retinyl esters, the storage forms of vitamin A (By similarity). Contributes to the activation of a signaling cascade that depends on retinol transport and LRAT-dependent generation of retinol metabolites that then trigger activation of JAK2 and its target STAT5, and ultimately increase the expression of SOCS3 and inhibit cellular responses to insulin (PubMed:21368206, PubMed:23839944). Important for the homeostasis of vitamin A and its derivatives, such as retinoic acid and 11-cis-retinal (PubMed:22467576, PubMed:24852372). STRA6-mediated transport is particularly important in the eye, and under conditions of dietary vitamin A deficiency (PubMed:22467576, PubMed:23839944, PubMed:24852372). Does not transport retinoic acid (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1-4 encode the same protein. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG209916 | Stra6 (tGFP-tagged) - Mouse stimulated by retinoic acid gene 6 (Stra6) |
CNY 6,370.00 |
|
| MG218391 | Stra6 (tGFP-tagged) - Mouse stimulated by retinoic acid gene 6 (Stra6) transcript variant 2, (10ug) |
CNY 6,370.00 |
|
| MR218391 | Stra6 (Myc-DDK-tagged) - Mouse stimulated by retinoic acid gene 6 (Stra6), transcript variant 2 |
CNY 4,912.00 |
|
| MR218391L3 | Lenti ORF clone of Stra6 (Myc-DDK-tagged) - Mouse stimulated by retinoic acid gene 6 (Stra6), transcript variant 2 |
CNY 7,700.00 |
|
| MR218391L4 | Lenti ORF clone of Stra6 (mGFP-tagged) - Mouse stimulated by retinoic acid gene 6 (Stra6), transcript variant 2 |
CNY 7,700.00 |
