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Klrk1 (NM_033078) Mouse Untagged Clone
CAT＃: MC204602
Klrk1 (untagged) - Mouse killer cell lectin-like receptor subfamily K, member 1 (Klrk1), transcript variant 1, (10ug)
CNY 2,400.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | D6H12S2489E; NKG2-D; Nkg2d |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC057147
AAATAACAAAAACTACAACCTGGATCAGTTTCTGAAGTAAATCTCTCATAATTCTCACATAATGGCATTG ATTCGTGATCGAAAGTCTCATCACTCAGAGATGAGCAAATGCCATAATTACGACCTCAAGCCAGCAAAGT GGGATACTTCTCAAGAACAACAGAAACAAAGATTAGCACTAACTACCAGTCAACCTGGAGAAAATGGTAT CATAAGAGGAAGATACCCTATAGAAAAACTCAAAATATCTCCAATGTTCGTTGTTCGAGTCCTTGCTATA GCCTTGGCAATTCGATTCACCCTTAACACATTGATGTGGCTTGCCATTTTCAAAGAGACGTTTCAGCCAG TATTGTGCAACAAGGAAGTCCCAGTTTCCTCAAGAGAGGGCTACTGTGGCCCATGCCCTAACAACTGGAT ATGTCACAGAAACAACTGTTACCAATTTTTTAATGAAGAGAAAACCTGGAACCAGAGCCAAGCTTCCTGT TTGTCTCAAAATTCCAGCCTTCTGAAGATATACAGTAAAGAAGAACAGGATTTCTTAAAGCTGGTTAAGT CCTATCACTGGATGGGACTGGTCCAGATCCCAGCAAATGGCTCCTGGCAGTGGGAAGATGGCTCCTCTCT CTCATACAATCAGTTAACTCTGGTGGAAATACCAAAAGGATCCTGTGCTGTCTATGGCTCAAGCTTTAAG GCTTACACAGAAGACTGTGCAAATCTAAACACGTACATCTGCATGAAAAGGGCGGTGTAAAAACTTTCAT TACCCATCTCAGCAACAACCAGAACAAGAGAATTGTCTCGGGAGAAATTGGGACTAAGAAGAAGAGACTG GGCATAAGACAAAAGCAAAACAGCAGGTCTGCACCCTCCACCAAATGATTAGCTAAACACATTGTGTTCC CATAAAACAAGGGAAGCCTGTGGGGCCAAGGAACCATGAGACAGGGGAAGAGGGAACAGGAGGACCAAGA GTGTGGTTGAAGCCTATCCAAACTAGGGAAATATGGTCCTGCCCTACTGGAGGAGGTGGTGTTGCCCAGT AGACTCTCAGCACCTTGATTTCCTCCCAGATATCCCCTACTCACTCTCTAAAGGTTTAAATTAAATATGA TATTTTATTCAAGATGCCTCTAGAGAGTCTAGACTCTATTTTTGTAGTGGTCACCGAGGCCTGAGGTCTT TTCACTCCTGGCAGTTCTTGCCTCACTTCCCCTCTCAGGGTCTGCTATTGTGATCATTGGTTGATCATGC TGCTTCTAGGATATGGGGAAGAAGACGAGGAGGAGCTTCCATTTCAAGATGGAATCAAAACAGAGGAACT GTGAGAACTGGAGAATAAAACCCTATAGCTCACTGGGAGCTTAATCTCCAGCACTATGGAAAACTGATGG CTGGGTATAGCCACAGCAGGGACCACAGGGAGTGCTGTGCCTGGCAGTGTTGCCATCTCAGTGACTCAAG AAAGCAGCCTGCTGTCTGGGAGGGACAGCAGAGACTCTCTGAGAAAGGTCAAGCAGGACTGCTTTTGGAA CTTGACAATCTCATGGAACTCACTTTGTTGATTTTTGTGCTTTCTTGGGATTCTCCCACTCTTTCATATG CTTTCCACTTGAGATGACAGTGTCTGTTGAAAGCAAGGCACTATATTTGAAAGTATATAGCTTGTTTCAC TTTACAAGTCAGAAAGGTGGTGCTGGAAGGAGTTGTCAGCTCTGTGGTTGTTAGGGTAGAATGGATACAG TTTGCAAGTGAGGAGATGGACTCCTGGAGCCATGGGTATAAGTTATACACCAAATGATTTTGTATTTTGT ACCTCCACGTTTCATATTTAAAATTCAAACTCCAGGTATTAATATGAGGAGACAGGCACTGGATCATAAT GTTTTAAATCATAAGGATAAAGGCTTTGTAAGTGGGATTACAAGAAATGGAGTTAGTTTTGCCTCTTAAG AATGCACCCAGGCGGGGCTGGTGAGATGGCTCAGTGGGTAAGGGCACCCGACTGCTCTTCCGAAGGTCCT AAGTTCAAATCCCAGCAACCACATGGTGGCTCACAACCACCCGTAATGAGATCTGATGCCCCCTTCTGGT GTATCTGAAGACAACTACAGTGTACTTACATATAATAAATAAATAAATCTTTAAAAAAAAAAAAAAAAAA |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_033078 |
| Insert Size | 699 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC057147, AAH57147 |
| RefSeq Size | 2170 bp |
| RefSeq ORF | 699 bp |
| Locus ID | 27007 |
| UniProt ID | O54709 |
| Gene Summary | Function as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-expressing tumor cells. Signaling involves calcium influx, culminating in the expression of TNF-alpha. Participates in NK cell-mediated bone marrow graft rejection. May play a regulatory role in differentiation and survival of NK cells. Binds to ligands belonging to various subfamilies of MHC class I-related glycoproteins including RAET1A, RAET1B, RAET1C, RAET1D, RAET1E, H60 and MULT1.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by mRNA and EST alignments. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG202802 | Klrk1 (tGFP-tagged) - Mouse killer cell lectin-like receptor subfamily K, member 1 (Klrk1), transcript variant 1 |
CNY 2,850.00 |
|
| MR202802 | Klrk1 (Myc-DDK-tagged) - Mouse killer cell lectin-like receptor subfamily K, member 1 (Klrk1), transcript variant 1 |
CNY 2,400.00 |
|
| MR202802L1 | Lenti ORF clone of Klrk1 (Myc-DDK-tagged) - Mouse killer cell lectin-like receptor subfamily K, member 1 (Klrk1), transcript variant 1 |
CNY 4,750.00 |
|
| MR202802L2 | Lenti ORF clone of Klrk1 (mGFP-tagged) - Mouse killer cell lectin-like receptor subfamily K, member 1 (Klrk1), transcript variant 1 |
CNY 4,800.00 |
|
| MR202802L3 | Lenti ORF clone of Klrk1 (Myc-DDK-tagged) - Mouse killer cell lectin-like receptor subfamily K, member 1 (Klrk1), transcript variant 1 |
CNY 4,750.00 |
|
| MR202802L4 | Lenti ORF clone of Klrk1 (mGFP-tagged) - Mouse killer cell lectin-like receptor subfamily K, member 1 (Klrk1), transcript variant 1 |
CNY 4,800.00 |
