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Uvrag (NM_178635) Mouse Untagged Clone
CAT＃: MC204184
Uvrag (untagged) - Mouse UV radiation resistance associated gene (Uvrag), (10ug)
CNY 5,120.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 9530039D02Rik; AI648770; BB124205; Uvrag1; Uvragl |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC034176
GGCTCTTCCTTAGCCAGCGGCGGTGGCCAGCGCGGGCGCAGAGCTGCTGGGGCTCTCGGTGCCCGGTTTC TAGGCTGTAGGGGCTCTGCGAATCACAGCTCGGGAGGCAGCGGCCGATGCGGGAGGACTGCCCACCTGGC CGCTCGGCGGCTCAGGGGTCCAGATGAGCTCCTGCGCCTCGCTCGGGGGCCCGGTGCCCCTGCCACCCCC GGGCCCGTCCGCCGCGCTGACGTCCGGTGCCCCCGCGCGGGCCCTGCATGTGGAGCTGCCGTCTCAGCAG CGGCGTCTCCGACATCTCCGGAACATCGCTGCTCGGAACATTGTTAATAGAAATGGCCATCAGCTTCTGG ATACCTACTTCACTCTTCATTTGTGTGATAATGAGAAAATCTTTAAAGAATTTTATAGGAGTGAAGTGAT TAAGAATTCCTTGAATCCGACGTGGAGGAGTCTTGACTTTGGAATAATGCCGGATCGTCTGGATACATCT GTGTCCTGCTTTGTGGTGAAGATTTGGGGTGGGAAGGAAGAGGCCTTTCAGCTGTTGATAGAGTGGAAAG TCTACCTGGATGGGCTGAAGTACTTGGGACAGCAGATCCATGCCCGCAACCAGAATGAAATCATTTTTGG GCTGAATGATGGCTACTACGGTGCTCCCTGTGAACACAAGGGTCATCCAAACGCACAGAAGAACCTCCTT CAGGTGGACCAGAACTGTGTTCGCAATTCTTACGATGTCTTCTCTTTGCTGCGGCTTCATAGAGCCCAGT GTGCAATTAAACAGACTCAGGTAACTGTTCAGAGACTTGGAAAGGAAATTGAAGAAAAACTAAGACTCAC ATCGACAAGCAATGAGCTGAAAAAAGAAAGTGAATGTCTGCGATTGAAAATTTTGGTGCTTCGAAATGAA CTGGAAAGACAGAAGAAAGCGCTGGGGCGGGAGGTGGCCTTCCTGCATAAGCAACAGATGGCTCTACAGG ACAAAGGAAGTGCATTTTCCACTGAGCATGGCAAGCTCCAGCTGCAGAAGGACTCCCTGAGTGAGCTGAG GAAGGAGTGTACTGCCAAAAGGGAACTCTTTCTGAAGACTAATGCTCAGTTGACCATCCGCTGCAGGCAG CTACTCTCAGAGCTGTCCTACATTTACCCTATTGATTTGAATGAGCACAAGGATTATTTTGTATGTGGTG TCAAGTTGCCTAATTCCGAGGACTTCCAAGCAAAAGAGGATGGAAGCATTGCCGTCGCCCTTGGTTACAC TGCACATTTGGTCTCCATGATCTCCTTCTTCCTACAAGTACCCCTCAGGTATCCCATAATTCACAAGGGG TCCAGATCAACAATCAAAGATAACATCAACGACAAGCTGACAGAAAAGGAGCGAGAGTTTCCACTGTATC CAAAGGGAGGGGAGAAGCTGCAGTTTGACTATGGTGTCTACCTTCTGAACAAGAACATAGCACAGCTGAG ATACCAGCATGGCCTGGGGACTCCAGACTTGAGGCAAACTCTTCCTAACCTGAAAAACTTCATGGAGCAC GGACTGATGGTCAGGTGTGACAGACATCACATCTCCAATGCCATCCCTGTCCCGAAGAGACAAAGCTCCA CGTTTGGGGGTGCAGATGGAGGCTTCTCTGCGGGTATCCCATCACCAGATAAAGTCCATCGCAAGCGGGC CAGCTCAGAGAACGAGAGACTCCAGTACAAAACCCCACCTCCCAGCTACAATTCAGCATTGACACAGCCC GGGGTGGCCATGCCCACCTCGGGAGACTCTGAGAGAAAGGTCGCCCCTCTGTCCTCCTCCCTGGACACCT CCCTGGACTTCTCCAAAGAAAACAAGAAAGCAGGAGTAGACCTGGGCAGCAGTGTGAGCGGAGACCACGG AAACTCGGACTCCGGCCAAGAGCAGGGGGAAGCCCTGCCTGGGCACCTGGCAGCCGTGAATGGCACTGCA CTGCCCAGCGAGCAGGCTGGCCCTGCCGGCACCCTGCTGCCAGGCTCGTGCCACCCGGCCCCCTCAGCTG AGCTCTGCTGTGCAGTGGAGCAAGCAGAGGAAATCATCGGGCTGGAAGCCACAGGCTTCACCTCGGGTGA CCAGCTGGAGGCGCTCAGCTGCATCCCGGTGGACAGCGCAGTGGCAGTGGAGTGTGACGAGCAGGTGCTG GGGGAGTTTGAGGAGTTCTCTCGCAGGATCTATGCCCTCAGCGAGAACGTGTCCAGCTTCCGCCGGCCTC GCAGGAGTTCTGACAAGTGAGGCAGGCAGGCAGGCAGGCAGGCAGGCAGACCGTAGGACCAGGGAGAGCC GCTGCCCTCCCTGGGGCCGAGCTTCACTTCATCTTTGAATAATTCCGACACAAATGATGTCAGTGGAGCA GATTCCTCGTAAAGGCTGACTTTGGGAACTGAGGGGACTCAGGGTCATTGGGTACCAGTGGGGCCAGTTC GTGAGATTAGCTTTCCAGGCCTGGCGGTTGTTTCTGGGCAAAGGTCGCCCTCTGCTTACAGCTCAAGTCC CGTTATAGGCATTTGTCTGCGGTTTATTTACACTTCTGTGTTCTCCTCAGAGGGAAGATGGGAATCTGTG TAACAGAAGGAGCTCACCTTTAGTTTCTCATAAGCATCCGCCCTCTCCATCATTTGGAACACTTTGCAAA ATGGAATATTCAAAAATAACTTTCCACCCTTGAGAGGCCTGTACCCATCCTTTAGATTGAGAATAAGAAA CAGTGTGATGGTCTCTGTTCCGGGCCCTCGGCCCTGAGAACCATAGTCAGCCTGCAGACCCCGCTGTTGC CCTGCTTCCTCAAGATGGGCCATGCATCCTGAAAGATGGGGCAATAAACCCACTAGTCCAAAGCCAGCAG GAATGATGTTCTGTCTCTGTCTAGTGTGCCATACCCTCATGAAAAATTGTCCTGTGGTGGACCCCAGGGG ACCCTAAGAAACCTCACGTTTACCACAGTCAGATGGCAGCCAGATTTCTTTGGGGGCCAAAGTTTTTATG TGGTCCAAAATTGGGCACACCTCTGGCAATACACACCCCAGATAAAGACCCCCTAGATATAAATCCTGTT AACTTATTACTTTTCCGTCAGAAGGAAGCCATTATACATGACAAAGCATAGGGAGAGGCAGGATGCCCAG TGTGCAGACCACGAGACAGTTGAGATAGTTGGGTTAAGAGACTAGACAAAGCATAGCTGTGTGCAACGTC ACGATGTTCAATTATGTTTCTAAGTCCATTGTCCCTGCACATTCAGACTCCATTCGCTGTTGCATTATAC ATTATGTACCCACAGACATTGCCTCAGGGTTGCAAGCTCTTAAAAGAAAAATTTATCCACATATCCATGT ATTGTAAAGAAGAATAAAAGTTGAATTTACTTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AA |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_178635 |
| Insert Size | 2097 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | BC034176, AAH34176 |
| RefSeq Size | 3432 bp |
| RefSeq ORF | 2097 bp |
| Locus ID | 78610 |
| UniProt ID | Q8K245 |
| Gene Summary | Versatile protein that is involved in regulation of different cellular pathways implicated in membrane trafficking. Involved in regulation of the COPI-dependent retrograde transport from Golgi and the endoplasmic reticulum by associating with the NRZ complex; the function is dependent on its binding to phosphatidylinositol 3-phosphate (PtdIns(3)P). During autophagy acts as regulatory subunit of the alternative PI3K complex II (PI3KC3-C2) that mediates formation of phosphatidylinositol 3-phosphate and is believed to be involved in maturation of autophagosomes and endocytosis. Activates lipid kinase activity of PIK3C3. Involved in the regulation of degradative endocytic trafficking and cytokinesis, and in regulation of ATG9A transport from the Golgi to the autophagosome; the functions seems to implicate its association with PI3KC3-C2. Involved in maturation of autophagosomes and degradative endocytic trafficking independently of BECN1 but depending on its association with a class C Vps complex (possibly the HOPS complex); the association is also proposed to promote autophagosome recruitment and activation of Rab7 and endosome-endosome fusion events. Enhances class C Vps complex (possibly HOPS complex) association with a SNARE complex and promotes fusogenic SNARE complex formation during late endocytic membrane fusion. In case of negative-strand RNA virus infection is required for efficient virus entry, promotes endocytic transport of virions and is implicated in a VAMP8-specific fusogenic SNARE complex assembly.[UniProtKB/Swiss-Prot Function] |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG210112 | Uvrag (tGFP-tagged) - Mouse UV radiation resistance associated gene (Uvrag) |
CNY 7,600.00 |
|
| MR210112 | Uvrag (Myc-DDK-tagged) - Mouse UV radiation resistance associated gene (Uvrag) |
CNY 6,940.00 |
|
| MR210112L3 | Lenti ORF clone of Uvrag (Myc-DDK-tagged) - Mouse UV radiation resistance associated gene (Uvrag) |
CNY 8,840.00 |
|
| MR210112L4 | Lenti ORF clone of Uvrag (mGFP-tagged) - Mouse UV radiation resistance associated gene (Uvrag) |
CNY 8,840.00 |
