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Ackr3 (NM_007722) Mouse Untagged Clone
CAT＃: MC203863
Ackr3 (untagged) - Mouse chemokine (C-X-C motif) receptor 7 (Cxcr7), (10ug)
CNY 3,656.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AW541270; Cmkor1; CXC-R7; CXCR-7; Cxcr7; RDC-1; Rdc1 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC015254
ACCACAGCCCAGGAAGCCCTGAGGTCACTTGGTCGCTCTCCTCAAGACCATGGATGTGCACTTGTTTGAC TATGCAGAGCCTGGCAACTACTCTGACATCAACTGGCCATGTAACAGCAGCGACTGCATTGTGGTGGACA CTGTGCAGTGTCCCACCATGCCTAACAAGAACGTGCTTCTGTATACCCTCTCCTTCATCTACATTTTCAT CTTCGTGATCGGCATGATTGCCAACTCTGTGGTGGTCTGGGTGAATATCCAGGCTAAGACCACAGGCTAC GACACGCACTGCTACATCTTGAACCTGGCCATTGCAGACCTGTGGGTCGTCATCACCATCCCCGTCTGGG TGGTCAGTCTCGTGCAGCATAACCAGTGGCCCATGGGGGAGCTCACATGCAAGATCACACACCTCATTTT CTCCATCAACCTCTTTGGGAGCATCTTCTTCCTCGCCTGCATGAGCGTGGACCGCTATCTCTCCATCACC TACTTCACCGGCACCTCCAGCTATAAGAAGAAGATGGTACGCCGTGTTGTATGCATCTTGGTGTGGCTGC TGGCCTTCTTTGTGTCCCTGCCTGATACCTACTACCTGAAGACGGTCACATCTGCTTCCAACAATGAGAC CTACTGCAGGTCCTTCTACCCCGAGCACAGCATCAAGGAGTGGCTGATCGGCATGGAGCTGGTCTCTGTC ATCTTGGGCTTTGCTGTCCCCTTCACTATCATTGCGATCTTCTACTTCCTGCTCGCTAGAGCCATGTCAG CATCAGGCGACCAGGAGAAGCACAGTAGCCGGAAGATCATCTTCTCCTACGTGGTGGTCTTCCTGGTATG TTGGCTGCCGTACCATTTTGTGGTTCTGCTGGACATCTTCTCCATCTTACACTACATCCCGTTTACCTGT CAGCTGGAGAATGTGCTCTTTACAGCGTTGCATGTCACCCAGTGCCTGTCCTTGGTGCACTGCTGTGTCA ACCCCGTGCTCTATAGCTTCATCAACCGCAACTACAGGTACGAGCTGATGAAGGCCTTCATCTTCAAGTA CTCGGCCAAAACAGGTCTCACCAAGCTCATTGATGCCTCCAGAGTGTCAGAGACAGAGTACTCTGCCCTG GAACAGAACACCAAGTGATCCATCATTCTGCAGAGGTCGGGGGGACACGTGCATGTTGCAAATGGGGCGG CTGGGTCCTGTGGTTTCTTCAAGAAAGCAATGTAGCTTTGGGTCTGGTTGCTTGAGTGGTATGAAGAGGA GAAGGCATGTGACCATGCTTCCTGTCTCTCATTCTCCAGCCAAGATGGCTGCCGCCTGGATGCCCATCCT GACAGCTGGCAGCTGGCAGCAGGCAGGGCTGTGCTGTGCTGTGCTGTGCTGCGCTGTGCTGTGCTGTGCA GCCAGAGCTGCGTATCAAAGCCAGCACCAGGACAGGATCTTATGGACATGTGTACAGTAGAATCTTCTGT GTTTCTTCAAGTTTTTACTTGGTGACTTTTTGTATTTAAGTTTTAAGACTTTATTTTCTCACTATGGATG TACCTTATAAATGTATTTGAAAGCTAAATATATTTTAAATATTGTATGGGAGGTGTAAGGCTGTTGTATT CAGACCATGTAGGCCTCAGATTAGCTGGACTTGAGTTTTGACTAAGGATGACATTAATTGTTAGCTGATT TGAAATTATATATATAAATATAAAAATATATATAAATTTATGCCAGTCTCGGCTGAAAGGTTTTATTTAC AATAGTTTTATATCTGTGCAATGTTTAATGCTGGCACAGCATATGAAACAACAACTGCCCAGCAATGCAG TTTGTTACATGAACCATATTGTAGAGTTACACTTCGGGCTGCAAACCCGTGAACAAGGGAAACAGAGCGT TCTGTTGATTTGTAAGTTATTTTTTTAATAAAGATTTTGTTTCCTAAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_007722 |
| Insert Size | 1089 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC015254, AAH15254 |
| RefSeq Size | 1960 bp |
| RefSeq ORF | 1089 bp |
| Locus ID | 12778 |
| UniProt ID | P56485 |
| Gene Summary | Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Acts as a receptor for chemokines CXCL11 and CXCL12/SDF1. Chemokine binding does not activate G-protein-mediated signal transduction but instead induces beta-arrestin recruitment, leading to ligand internalization and activation of MAPK signaling pathway. Required for regulation of CXCR4 protein levels in migrating interneurons, thereby adapting their chemokine responsiveness. In glioma cells, transduces signals via MEK/ERK pathway, mediating resistance to apoptosis. Promotes cell growth and survival. Not involved in cell migration, adhesion or proliferation of normal hematopoietic progenitors but activated by CXCL11 in malignant hemapoietic cells, leading to phosphorylation of ERK1/2 (MAPK3/MAPK1) and enhanced cell adhesion and migration. Plays a regulatory role in CXCR4-mediated activation of cell surface integrins by CXCL12. Required for heart valve development.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG205565 | Cxcr7 (tGFP-tagged) - Mouse chemokine (C-X-C motif) receptor 7 (Cxcr7) |
CNY 5,256.00 |
|
| MR205565 | Cxcr7 (Myc-DDK-tagged) - Mouse chemokine (C-X-C motif) receptor 7 (Cxcr7) |
CNY 3,656.00 |
|
| MR205565L3 | Lenti ORF clone of Cxcr7 (Myc-DDK-tagged) - Mouse chemokine (C-X-C motif) receptor 7 (Cxcr7) |
CNY 4,750.00 |
|
| MR205565L4 | Lenti ORF clone of Cxcr7 (mGFP-tagged) - Mouse chemokine (C-X-C motif) receptor 7 (Cxcr7) |
CNY 6,056.00 |
