Akr1b3 (NM_009658) Mouse Untagged Clone

CAT#: MC203763

Akr1b3 (untagged) - Mouse aldo-keto reductase family 1, member B3 (aldose reductase) (Akr1b3), (10ug)



  "NM_009658" in other vectors (4)

CNY 2,400.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (4)
AKR1B1 Antibody - middle region
    • 100 ul

CNY 5,250.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Mouse Untagged Clone
Tag Tag Free
Synonyms Ahr-1; Ahr1; Akr1b1; Aldor1; Aldr1; ALR2; AR
Vector PCMV6-Kan/Neo
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>BC021655
CCACGCGTCCGTTTAAAGGTGCGCGCCCGAGCCAGCGCTGCACATTTGCCGGTCCGGGTTTGTAACGTGC AGCGATCATGGCCAGCCATCTGGAACTCAACAACGGCACCAAGATGCCCACCCTGGGCCTGGGCACCTGG AAGTCCCCTCCTGGCCAGGTGACTGAGGCCGTGAAAGTTGCTATTGACTTGGGGTACCGCCACATTGACT GCGCCCAGGTGTACCAGAATGAGAAGGAGGTGGGAGTGGCCCTCCAGGAGAAGCTCAAGGAGCAGGTGGT GAAGCGGCAGGATCTCTTCATTGTCAGCAAGCTGTGGTGCACGTTCCATGACAAGAGCATGGTGAAAGGA GCCTTCCAGAAGACACTGAGCGACCTGCAGCTGGACTACCTGGATCTCTACCTTATTCACTGGCCAACGG GGTTCAAGCCTGGGCCCGACTATTTCCCACTGGATGCCTCAGGGAACGTGATACCTAGTGACACCGATTT TGTGGACACTTGGACGGCTATGGAACAACTAGTGGATGAAGGTTTGGTGAAAACAATCGGTGTCTCCAAC TTCAACCCTCTTCAGATTGAGAGGATCTTGAACAAACCTGGCTTAAAATATAAGCCTGCGGTGAACCAGA TCGAGTGCCACCCGTACCTAACTCAGGAGAAGCTGATTGAATACTGCCACAGCAAAGGCATCGTGGTGAC AGCATATAGTCCCCTTGGTTCTCCTGACAGGCCCTGGGCCAAGCCTGAAGATCCGTCTCTCCTGGAGGAT CCCAGGATCAAAGCAATTGCAGCCAAGTACAATAAAACTACAGCCCAGGTGCTGATCCGGTTCCCCATTC AGAGGAACTTGGTAGTGATCCCCAAGTCGGTGACACCAGTGCGCATTGCTGAGAACTTGAAGGTCTTTGA CTTTGAGCTGAGCAGCGAGGACATGGCCACTCTACTCAGCTACAACAGGAACTGGAGGGTGTGCGCCTTG ATGAGCTGTGCCAAACACAAGGATTACCCCTTCCACGCCGAAGTCTGAAGCTGTGGCGAGCGGATCCCTG CTCCTCCTCAAGTGGCTTGCACCTGTTCTTTCTGCCTCATCTGCCCTTGCAAGTGTCCTGTGTCTGCACT AGGTGGCACCTTGCAAACCAGATGGTGAGAGTTAGTTAGTTTGACATAGAGTCTGGAGGGCAGTACCAGT AGCCAAGGTGTTTCTTCCAGCCTTCCTTGGTCTTTCTTCTTACCCCCCTGGAGGACTTTAACACAAGTAC CCTTTCCAACCAAAGAGAAGCAAGCTTTAGAGTCCAAGCCGTGCCACTAACACTTAAATGTGAGTGCTTA GAACTGTAATCCTTTGGGTCAGACTTCTCCTTGCCTCAAATAAAAACTGCTTTTGTGAAAAAAAAAAAAA AA
Restriction Sites RsrII-NotI     
ACCN NM_009658
Insert Size 951 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq BC021655, AAH21655
RefSeq Size 1402 bp
RefSeq ORF 951 bp
Locus ID 11677
UniProt ID P45376
Gene Summary Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols (PubMed:17381426, PubMed:19010934, PubMed:7851421). Displays enzymatic activity towards endogenous metabolites such as aromatic and aliphatic aldehydes, ketones, monosacharides, bile acids and xenobiotics substrates. Key enzyme in the polyol pathway, catalyzes reduction of glucose to sorbitol during hyperglycemia. Reduces steroids and their derivatives and prostaglandins (PubMed:19010934). Displays low enzymatic activity toward all-trans-retinal, 9-cis-retinal, and 13-cis-retinal. Catalyzes the reduction of diverse phospholipid aldehydes such as 1-palmitoyl-2-(5-oxovaleroyl)-sn -glycero-3-phosphoethanolamin (POVPC) and related phospholipid aldehydes that are generated from the oxydation of phosphotidylcholine and phosphatdyleethanolamides (PubMed:17381426). Plays a role in detoxifying dietary and lipid-derived unsaturated carbonyls, such as crotonaldehyde, 4-hydroxynonenal, trans-2-hexenal, trans-2,4-hexadienal and their glutathione-conjugates carbonyls (GS-carbonyls) (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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