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Abr (NM_198018) Mouse Untagged Clone
CAT＃: MC203476
Abr (untagged) - Mouse active BCR-related gene (Abr), transcript variant 1, (10ug)
CN¥ 6,384.00
货期*
现货
规格
Product images
经常一起买 (3)
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 6330400K15Rik; AU042359 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC058708
TCGTCCTGCCTCCCGCTCCCACTGTTAATTTTTAGACGTGGAATTAGGCAGGAGGCAAAGGAAACACAGC CCCACATACGCAGCTGACATGCTATTAGGCGGGTGGAGACAGCAGAACCGCTCCTCCCCGACTCCCAGCA GCCTCTGACGGACTCAGCAGAGCCTGTGCCTGCTGGAGCTCCCACCCCCCTCCCCAAGCCTGGCTGTACA GCCCCTGCCCTGGCCCAGGGTGCATGGTGCAGCAGGGGCCATGGCAGCCGGGGGCCGCCGCCGGCGCCCA CTGCGCTACCAGTCCCTGGCAGCCCTGGTGGAAGACTCTCAGTGGCCTTTCTTGTTCCTTGTCTCAGACT TCAGCTACGGTGCGGAGGACTACGACGCAGAGGGGCATGAGGAGCAGAAGGGGCCCCCCGAGGGCTCGGA GACCATGCCGTACATCGACGAGTCACCCACCATGTCGCCCCAGCTCAGCGCCCGCAGCCAAGGTGGTGGG GACAGCGTCTCGCCCACCCCACCTGAGGGATTGGCACCTGGGGTGGAGGCAGGGAAGGGTCTGGAGATGA GGAAGCTAGTCCTCTCTGGGTTTCTGGCCAGTGAAGAGATCTACATTAACCAGCTGGAAGCTCTGTTACT GCCCATGAAACCCCTGAAGGCCACAGCCACCACCTCCCAGCCTGTGCTCACCATCCAACAGATTGAGACC ATCTTCTACAAGATCCAGGACATCTACGAGATCCACAAGGAGTTCTACGACAACCTCTGCCCCAAGGTGC AGCAGTGGGACAGCCAGGTCACCATGGGCCATCTTTTCCAGAAACTGGCCAGCCAGCTTGGCGTGTACAA AGCATTTGTGGATAACTATAAAGTCGCTCTGGAGACAGCCGAGAAGTGCAGCCAGTCCAACAACCAGTTC CAGAAGATCTCTGAGGAACTCAAAGTGAAAGGGCCCAAGGACTCTAAGGACAGCCATACATCAGTCACCA TGGAAGCTCTGCTGTACAAGCCAATTGACCGAGTCACCCGGAGCACCCTGGTCCTTCACGATCTGTTGAA GCACACACCCGTGGACCACCCGGACTACCCGCTGCTTCAGGATGCTCTCCGCATCTCCCAGAATTTCCTG TCTAGCATTAACGAGGACATTGATCCTCGCCGGACTGCAGTCACAACCCCCAAGGGAGAGACTCGGCAGC TGGTGAAGGACGGCTTCCTGGTGGAAATGTCTGAGAGCTCCCGGAAGCTGCGGCATGTCTTTCTCTTCAC AGATGTTCTGCTGTGTGCCAAGCTAAAGAAGACCTCAGCAGGAAAGCATCAGCAGTATGACTGTAAGTGG TACATCCCTCTGGCTGACTTAGTGTTCCCATCCCCTGAGGAGTCAGAGGCCAGTCCCCAGGTGCACCCCT TCCCAGACCACGAGCTCGAGGACATGAAAACGAAGATCTCTGCCCTCAAGAGTGAGATCCAGAAGGAGAA AGCCAACAAAGGACAGAGCCGAGCCATTGAGCGCCTCAAAAAGAAGATGTTTGAGAATGAGTTCTTACTG CTGCTCAATTCCCCAACGATCCCTTTCCGGATACACAATCGGAATGGAAAGAGTTACCTGTTTCTTCTGT CTTCTGACTATGAGAGGTCGGAGTGGAGAGAAGCGATTCAGAAGCTACAGAAGAAGGATCTCCAGGCCTT TGTCCTGAGCTCTGTGGAGCTCCAGGTGCTCACGGGATCCTGTTTCAAGCTTAGGACTGTGCACAACATT CCTGTCACCAGCAATAAAGATGATGATGAGTCTCCAGGACTGTACGGCTTCCTTCATGTCATCGTCCACT CTGCCAAGGGCTTTAAACAGTCAGCCAATCTTTACTGTACTCTGGAGGTGGATTCCTTTGGCTATTTTGT CAGCAAAGCCAAGACCAGGGTGTTTCGGGACACGACAGAGCCCAAGTGGGATGAGGAGTTTGAGATTGAG CTGGAGGGTTCACAGTCCCTGAGGATCCTGTGTTATGAGAAGTGCTACGACAAGACCAAGGTCAACAAAG ACAACAATGAGATTGTGGACAAGATCATGGGCAAGGGGCAGATCCAGCTGGATCCACAGACAGTAGAAAG CAAGAACTGGCATACGGACGTGATTGAAATGAATGGGATCAAAGTGGAATTCTCCATGAAATTTACCAGC CGTGACATGAGCCTGAAGAGGACCCCATCCAAAAAGCAGACAGGCGTCTTTGGAGTGAAGATCAGCGTGG TGACCAAGCGGGAGCGCTCCAAGGTGCCCTACATCGTCCGGCAATGCATAGAAGAGGTGGAGAAGAGGGG CATTGAGGAGGTTGGCATCTACAGGATATCAGGGGTGGCCACGGACATCCAGGCCCTGAAGGCTGTCTTT GATGCCAATAACAAGGACATCCTACTGATGCTGAGCGACATGGACATCAACGCCATCGCTGGGACCCTCA AGCTATACTTTCGGGAGCTGCCTGAGCCCCTCCTTACAGATAGACTTTATCCAGCCTTCATGGAGGGCAT TGCCCTGTCAGACCCTGCTGCCAAGGAGAACTGCATGATGCACCTACTCCGCTCCCTGCCTGACCCCAAC CTCATCACCTTCCTTTTCCTGCTGGAACACTTGAAAAGGGTTGCTGAGAAGGAGCCCATCAACAAGATGT CACTTCACAACCTTGCCACGGTGTTTGGCCCCACGTTACTGAGACCATCAGAAGTGGAGAGCAAAGCACA TCTCACATCAGCTGCAGACATCTGGTCCCATGATGTCATGGCCCAGGTCCAGGTCCTCCTCTACTACCTG CAGCATCCCCCCATTTCCTTCGCAGAACTGAAGCGGAACACACTGTACTTCTCCACAGACGTGTAGCCTG GGGTGGGCAGCTGTGGGGGCGGCCAGGGGCCAGCCCTCCAGCCGGGCCCCGACATAGACTTGAAAGACTG CAACAGAAACTCCCCAGCCTAGCACTCCAGAGTCCAAGGGAAGCCACCTTCCAAGAACTGGAACATGTGC ATCTTTTGTGCCACCTTGTACAAAGCCAGCTGACCAGCCCCCGCCTCCTCACCACACCCCAGCTCCTATC TTCTGTACCCGAGTGTGTCTGATGCTCCGTGCTGTCCAGGAATTGTTTTATGTATTATTGTCATTGCAGA AAAGGTAGTGGCCGAGCTGGTATGGGCACAGACAGATTGCTTTGTTCTTTCATTTCTCCCAGCACTCACT TTCTGCCTGAGTCCGGTCCAAGGACTTTTACTTTGCGCTTCGTAACTACTGCCAGCTTCTCCTCTCCTGG CCCTGCTCCCAGATTGCAGCCTCCCTGCAGTGTCTGCCCTTGCCACCTCCCAGCCTGCTGCATGCATGTG CAGCATGGGCTTTTGCTCCATCACCGCAAAGTTCTGCAGGGGCCCTGGGCAGTGCTGGCCTGTCTGACGT GCTGCCCTTGGCCTCCTTGCTCTCCACGTGTGGAAGCGCATCTGCTTTCCTTGCTGTCTGTGCAAATGCT GAACAAGGAGACAGACACACACTAATCCTCAGCACAGAGCTGGAAAGCTCATTTCTGGAATGTTCTATTT GAGAATTGCCATTTCTGGGGTTTGTCTGTTCTATCTCCTGCCTACCAGTCGGTATCTTCAGCTGTTTCTT CTATTGCTGGATTTTCTGTTCCTTTTCCCCAGTGTTCTGTTTTCTTTGAGTGTAATGACCCACAAGTGTC CTGCCATTAAGAGAGGTCAGGATTGCACCTGAAGGGTATGGTGGGCACCCAGGCTGTGAAGGAACAAGAT GAGTGGAGCGGCCAGCAGTGGCAAGTCAAGGGAAGCCAGTCTTCAGTGTAAGGACCCGCAGTGGCTATCC TAGTGTACATTCTCCTGGAGAGCAGCTTCTGTGGCTGAATCAGGTGTCCAGGTGAAGACAGGCCCTGTCC TGGAACCTGGAATCACACATACCTCGTGGTACTTTTGCCTTAGATTTTACACTCTCAACAGCCAAGCACT GCCACGGGGCAGCCACAATGCCATGCGTGCTCCAGAGCCTAGGAACAGCAGACAGAACCCAGTTGGAATG CTTCTACCCTGGCTTCTAAATTCAGGCCTGTGGGTAATCCCAAGTATACAGGAAATTGTGGGGTAGGCTG TCTCTCGTGAATTGAGTTCTGCTGGGGCTATAGAGCATCGGGTCGGCAGCTGTCATTCCCAGCTCTGTGA CCTACTGCTTGGTACTAAAAAGGAGTTTTCTTCCAAAAGCACTGTTTCCAGTCTGAGTAGGAGCTACCAG CCTGTGGCAATCAGCAGGGAAAGACAGGTGCTCCTGTCATAGGGGCTTGAGCTACCACAGCTACCACACA GCTTTCTGGATCTTCTATATGGCAGTTCATTCTTGGCCCTCAGGATTGGGGAGACCAGCTCTCATTGTGT GTGCTCAGGGCTAAGTCTAAACAAGGGTTTGCTGGCCCCCAAGCTGTTGTTTGTTAGGTGAGGTTAAGTA GGGCTCTTCTGGTCCTGTGCATACCTATTGCCTTTGACAGAACGGTACAGTTTGTTTATGCAGGAGGATG GCATGCCAACTTCCCAGCTGCCTACTAGCAGTTTAACAAGGAGCCTTGCTGTCTCAGACAGGTGAAAGAA AATGTCATGCATGTAAAGATCACATCTGCCACTACCTTGGCACTCAGGTGCTGGTATGTGCATTCTTGCT TCCAAAGGATTGACAGTAACAAATTCTCAAAGCTTGACTGGAGCTGGCTGCAGCTCAAAACAGTGCCTCC TGCCTCTTTAGAGCGGGGCTGCTCGGCAGCAGTGACTGCAGCCCCAGCTTGCTTAAGCAGTGTAACAGCA GGGAAGCGGGAGGAGCTGAGAACTATTAGAAGTTCCTATTATTTATAAATTCCACCCAAAGTGGACAGAG TCAGGTGCCAGACCTGATCTGAAGTGCACCAAGGAAGTATCTGGTGGTTCTCCTGAGATGGGGGCCTTGC AGCCCAGCACCCCCTCACTGCCAGCAGGGCACCAGGAGACAGGGTCCAGGAATCCAGGTATGCCTGTACT TGCTTGAGCAACGACTGAGGGCTGCCAGCTTTTGCTGACAAGGTAGGATGGGACCCCCAATAAGTGGGTA TGGATATATTTTTTTTTGTCTCTGTTCTGTTTAAACTTATGTAGATTATTATAAATTGATGTAAACCATG TGAGAGGGAAATGTTAATAAAAAAATTGCAAAGCCTCAACATTTGCACAAAACTCAAAAAAAAAAAAAAA AAAAAAAAAAAAA |
| Restriction Sites | AscI-NotI |
| ACCN | NM_198018 |
| Insert Size | 2616 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC058708, AAH58708 |
| RefSeq Size | 5263 bp |
| RefSeq ORF | 2616 bp |
| Locus ID | 109934 |
| UniProt ID | Q5SSL4 |
| Gene Summary | Protein with a unique structure having two opposing regulatory activities toward small GTP-binding proteins. The C-terminus is a GTPase-activating protein domain which stimulates GTP hydrolysis by RAC1, RAC2 and CDC42. Accelerates the intrinsic rate of GTP hydrolysis of RAC1 or CDC42, leading to down-regulation of the active GTP-bound form. The central Dbl homology (DH) domain functions as guanine nucleotide exchange factor (GEF) that modulates the GTPases CDC42, RHOA and RAC1. Promotes the conversion of CDC42, RHOA and RAC1 from the GDP-bound to the GTP-bound form (By similarity). Functions as an important negative regulator of neuronal RAC1 activity (PubMed:20962234). Regulates macrophage functions such as CSF-1 directed motility and phagocytosis through the modulation of RAC1 activity (PubMed:17116687).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) contains a different segment in the 5' UTR and CDS, compared to variant 3, resulting in a protein (isoform 1) that has a longer and distinct N-terminus, compared to isoform 3. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MR211021 | Abr (Myc-DDK-tagged) - Mouse active BCR-related gene (Abr), transcript variant 1 |
CN¥ 6,384.00 |
|
| MR211021L3 | Lenti ORF clone of Abr (Myc-DDK-tagged) - Mouse active BCR-related gene (Abr), transcript variant 1 |
CN¥ 9,600.00 |
|
| MR211021L4 | Lenti ORF clone of Abr (mGFP-tagged) - Mouse active BCR-related gene (Abr), transcript variant 1 |
CN¥ 9,600.00 |
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