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Pcgf2 (NM_009545) Mouse Untagged Clone
CAT＃: MC202903
Pcgf2 (untagged) - Mouse polycomb group ring finger 2 (Pcgf2), transcript variant 1, (10ug)
CNY 2,000.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | mel-18; Mel18; Rnf110; Zfp144 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC016419 sequence for NM_009545
GTCTCTCTCTCTTTTTTTTTCCTTTCCTCCCTTCCAAGATGGCCGAAGTGGATTCCCCCTCTTAACGATT TGGAGTCTCCCTCGACCACCTCCTCTTTGTGCAGCAGCCCCCTGCTAAGACCCTGCTTGCGAGGCAGGAA ACAGCCTCCAGGATCCAGTCCGGCTGTCGCGTCGCCTGATCCTGTTCAAGTTGAAGGCTTGGGAGGGTGA CACTTCCCAAATCTCCTCAGTCCTGACCCCGGCATCATGCATCGGACCACACGGATTAAAATCACGGAGC TGAACCCTCACCTCATGTGTGCCCTCTGTGGGGGCTATTTTATTGATGCCACCACCATTGTGGAATGCTT ACATTCCTTCTGCAAAACCTGCATCGTACGCTACTTGGAGACCAACAAATACTGCCCCATGTGTGACGTC CAGGTCCATAAAACTCGACCACTGCTGAGCATCAGATCAGACAAAACCCTCCAGGACATTGTCTACAAGT TGGTGCCTGGGCTTTTTAAAGATGAAATGAAACGGCGACGGGACTTCTATGCAGCATACCCCCTGACAGA GGTCCCCAACGGCTCCAACGAGGACCGAGGCGAGGTCCTGGAACAGGAGAAGGGGGCTCTGGGTGACGAC GAGATTGTCAGTCTTTCCATTGAGTTCTACGAAGGCGTCAGGGACCGAGAGGAGAAGAAGAACCTCACGG AGAATGGAGATGGGGACAAGGAGAAGACAGGAGTGCGATTCCTGCGGTGCCCAGCAGCCATGACCGTCAT GCACCTGGCAAAGTTCCTCCGCAACAAAATGGATGTGCCCAGCAAGTACAAGGTGGAGATCCTCTATGAA GATGAGCCCCTGAAGGAATACTACACCTTAATGGACATTGCGTACATCTACCCCTGGCGAAGGAATGGGC CTCTCCCCCTCAAGTACCGTGTCCAGCCAGCCTGCAAGCGGCTCACCCTGCCCACGGTGCCAACCCCCTC AGAAGGCACCAACACCAGCGGGGCATCAGAGTGTGAGTCAGTCAGCGACAAGGCTCCCAGCCCTGCCACC CTTCCGGCCACCTCCTCCTCCTTGCCCAGCCCTGCGACCCCATCCCATGGCTCTCCCAGCTCCCACGGCC CCCCAGCTACCCATCCTACTTCCCCCACTCCACCTTCAACTGCCGCTGGGACCACCACAGCTACCAATGG GGGCACTTCGAACTGCCTGCAAACGCCATCCTCCACCAGCAGGGGGCGCAAGATGACTGTTAATGGCGCT CCTTGCCCCCCTTGAGGAAAGGGACCCTCTCCTTCCGCAGCCATCTTTTCCCTCCTTTTTACTTTTTCTG GGCCCCCTTTTCCACTTTTGACTTTCCCTGGTTCCTCCCATTTTCAGAGTGGGAGGTGGGTTTTATAAAT AAATCTATATATATATAAATATATATATGTACATAGGAAAAACCAAATATACATACTTATTTTCAAAAAA AAAAAAAAA |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_009545 |
| Insert Size | 1029 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | BC016419, AAH16419 |
| RefSeq Size | 1479 bp |
| RefSeq ORF | 1029 bp |
| Locus ID | 22658 |
| UniProt ID | P23798 |
| Gene Summary | Transcriptional repressor (PubMed:8521824). Binds specifically to the DNA sequence 5'-GACTNGACT-3' (PubMed:8521824). Has tumor suppressor activity (PubMed:8521824). May play a role in control of cell proliferation and/or neural cell development (Probable). Regulates proliferation of early T progenitor cells by maintaining expression of HES1(PubMed:15728456). Also plays a role in antero-posterior specification of the axial skeleton and negative regulation of the self-renewal activity of hematopoietic stem cells (PubMed:8625838, PubMed:15183898). Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Within the PRC1-like complex, regulates RNF2 ubiquitin ligase activity (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longest transcript. Variants 1-3 encode the same protein. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG205143 | Pcgf2 (tGFP-tagged) - Mouse polycomb group ring finger 2 (Pcgf2) |
CNY 3,140.00 |
|
| MG215739 | Pcgf2 (tGFP-tagged) - Mouse polycomb group ring finger 2 (Pcgf2) transcript variant 1, (10ug) |
CNY 3,140.00 |
|
| MR215739 | Pcgf2 (Myc-DDK-tagged) - Mouse polycomb group ring finger 2 (Pcgf2), transcript variant 1 |
CNY 3,656.00 |
|
| MR215739L3 | Lenti ORF clone of Pcgf2 (Myc-DDK-tagged) - Mouse polycomb group ring finger 2 (Pcgf2), transcript variant 1 |
CNY 4,750.00 |
|
| MR215739L4 | Lenti ORF clone of Pcgf2 (mGFP-tagged) - Mouse polycomb group ring finger 2 (Pcgf2), transcript variant 1 |
CNY 4,750.00 |
