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Abi2 (NM_198127) Mouse Untagged Clone
CAT＃: MC202487
Abi2 (untagged) - Mouse abl-interactor 2 (Abi2), transcript variant 3, (10ug)
CNY 3,656.00
货期*
现货
规格
Product images
经常一起买 (3)
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 8430425M24Rik; AI839867; C130078H13 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC056345 sequence for NM_198127
TGAAGATGGCGGAGCTGCAGATGCTGCTGGAAGAGGAAATCCCGGGGGGCCGCCGGGCTCTCTTCGACAG CTACACGAATCTGGAGCGGGTGGCCGACTACTGCGAGAATAACTACATCCAGTCACCAGATAAGCAGCGA GCCCTAGAAGAAACCAAAGCCTACACCACTCAATCCTTAGCAAGTGTTGCGTATCTGATAAACACCTTGG CCAACAATGTCCTACAGATGCTGGATATCCAGGCATCACAGTTACGGAGGATGGAGTCTTCAATCAACCA TATTTCACAAACAGTTGATATTCATAAAGAGAAGGTTGCAAGAAGAGAAATTGGTATTTTGACCACCAAT AAAAACACTTCAAGGACCCATAAGATTATTGCGCCAGCCAACCTTGAGCGGCCAGTTCGTTATATTCGAA AACCTATTGACTACACAATTTTAGATGACATTGGACATGGAGTGAAGGTGAGTACCCAGAATATGAAAAT GGGTGGATTGCCACGTACGACACCTCCAACTCAGAAGCCCCCAAGTCCCCCTATGTCAGGGAAGGGGACA CTTGGGCGGCACTCCCCCTATCGAACACTGGAGCCAGTGCGTCCTCCAGTGGTACCAAATGATTACGTAC CTAGCCCAACCCGTAATATGGCTCCCTCGCAGCAGAGCCCTGTGAGGACAGCTTCTGTGAATCAAAGAAA TCGAACTTACAGCAGCAGTGGGAGCAGTGGAGGAAGTCACCCAAGTAGTCGGAGCAGCAGTCGGGAGAAC AGCGGAAGTGGTAGTGTGGGGGTACCCATTGCTGTGCCTACTCCGTCTCCTCCAAGCGTCTTTCCAGGTC ATCCTGTTCAGTTCTACAGCATGAACAGGCCTGCCTCTCGCCATACACCACCTACAATAGGGGGCTCGTT GCCCTATAGACGTCCTCCTTCCATAACGTCACAAACAAGCCTTCAGAATCAGATGAATGGAGGTCCTTTT TATAACCAGAATCCAGTTTCAGATACACCACCTCCACCCCCACCTGTGGAAGAGCCAGTCTTTGATGAAT CCCCCCCTCCACCGCCTCCTCCAGAAGATTATGAAGAGGAGGAAGCAGCTGTGGTTGAGTACAGCGATCC GTACGCTGAAGAGGACCCACCGTGGGCGCCAAGGGCTTACTTGGAAAAGGTTGTGGCAATTTATGATTAT ACAAAAGACAAGGAAGATGAGCTGTCCTTTCAGGAAGGAGCCATTATATATGTCATCAAGAAGAATGACG ATGGTTGGTATGAGGGAGTTATGAATGGTGTGACCGGGCTCTTCCCTGGGAACTATGTTGAGTCCATCAT GCATTATTCGGAGTAGAGCCCGGCACAGCTGTGCTTCTCTCAGGAGGTCAGGTCTTCCCAGATTAGCTTG AGGCCCTGGGAATTTCCTCCCAGTGAAATGAATGAAGCATACAAATGATGAAGTTACTCCTTTTATTACT GTTTTGGTTTATCCCCTTGTATCAAAAACTGAAAGCCAAGTCTGAACAAGTGGATCTTCTTGCTGTCATT TGCATTATGCTGTCTAGATTGAAAATGTGACCATTTCTCAATCATGAAAGGCATACCAACATGAACATGT AGCTAAAACATGTAAGACCAAGACTGACTTGAGGAAAAATATCTGGGATCTTTCTCAGGAATACTGTACA CCCTTGGATTTCTCTTCCTGCAGAATCTGTGACATTGGATGCTCATTGCCTCTGCTTTGGGGCTAACCTC ATGGCCTGGTGGACACCCTTGCCCTTTACTTTCAGTATATGGAGAGGAAAGGAACCAGTGTTTAAATACT TTATTTAACTGCTTTTTGATTGCTTAAGGCTGTTTTCCTTCTTTAACACTGTAAACCCTGTGTTCTCTTA GCACTGGAGTGCGCTAGGTGAGTTAACCTTGAACTCCCTTGCACCCTGTCCTGTTTGTAGATTATAAGGA TGACAAAATGTGAAAGTCTCCAAATATTCCCAGGGTTGTTAACAGTTTGATTTTAATGCACTGTTGCATG AGACTGCATTGCTGATAGCAGCCAGTGAAAGCAATGTGAAATGTGGTGTAGGTACTTCATGTACTGAGGT GAGCTTGTTGGATACGAAGGTTCCTAAGGATCTCCAGCCTTAGGCTGTTTCAGAGCAGGAAGTCAGACCA GCTATTACTGTTCTTTTGATATTCAACCCCCCCACCCCACCTTTAATTTTTTAGCAGAGACTAGTGTTGT CAAGTCTCTTGACAGTCACTGGACTGGGAATGAAAGGCTGCTACCATGCTCTTGGACCATTATCAATGGC AGTGTTAGCTGATGCCAAGTCATTTTCAATCTCTCAGCTATAGAAAAATAAGTCTCCTCCTGATCTGAAG TGATTAGACTCTAAAGTGGCACTCCTAGTAATATTCTGAATTTTGTGATTCAGAGTGAAGAGTGTGCTGG AGAAGACTAATAGAATAAAATACTTGCCCAGTCACACTGAGGAAAATCAGTAGTATGTATTTGAAACTAT TGGCATCTCCCTCATCTACCGAAGAGGAAGTAAAGCTGTTGTAATCCAGATGCAGGCCTTGTACATGCTG TCTGGTGATGCTAGAAGAACAAGCGTTGTAGATGTGAAGAAAAGCAGACTATAAGGCACTGACACTCCAC TGGTAGATCCGCTATCTGCACCTGAGGCTTCACTGTGCAACTCGGACCCAGACAGTGTTCTTCTCAAGAC CTCTTTTGCTTTAAGGTTGTAGGTTTTGTTTGTTTCAGACATGGTGTCTTCCTGCTCTAGCCTCTCAAAT ACTAGGATTGTAAGGAGGAGCCACTGTACCAGGAGCAGCAGGCTGTTTTGGTTTTAATTTTATTTTAAAA CCACATTGCACATCAGCTATCACGCTTTTAGATGGTTTGTTTTTTTTGTTTTTTGTTTTTTTTTGTTTTT TTTTGGATTTTTTGAGATAGGCTTTCTCTGTATAGCCCAGGCTGTCCTGGAACTCACTTTGTAGACCAGG CTGGCCTCAAACTCAGAAATCCACCTGCCTCTGCCTGCCGAGTGCTGGGACTAAAGGCGTGCGCCACCAC CGCCCGGCTCACACTTTTAGAGTTTTTTTAGATGCTTTGGATTCTTTAACTTGCTTCTAGCACACGTTCC ACTTCATGGATTTGTTAGGTCATCTTGACTGTCTTCAGAATATATCCCTGAAGTCCTCTGAACCTTTAGT TCCATTATGGACCCAAGCAAGACTGTATATGAACGTTTAACTCTGATTGTATTGGTACATGGAAACTTTT GAAAAATAGTTGCACTAATTATTTATTTAAGTAGCCTTTTGTTGAACAAGCTTAGTTGACTAATAAGACG TTTGGAAACCCAGCAAACAACTAGCTTTTGTAGTCATAGAAACAACTGGTGGTAGGCACCAGGAATACAG TTTATCTTCTGGACTCCTGCTGAGTTGGGGTTTGCAGAAAACACTTGTGAAATCCTTTGTGCTGAAGACT TGCACTGGGGGTAATCCATGGGACAGATGACTCCCTCCCCCTTGTATTATTGAGTACTAATAGGGTTTAA AAACGAAACACAAAATACTCTATGTTGGCCTTTTCCCCCAATCTTAAATTTTTTCAATTTTGGATTCTAT GAATTGTTTTGGAAGGATACTCTGTAACAATGAGCCAGGCCTACAGTAATCGGAGACTTTTAATGTATGT AATATTTTATAGATTGCATGCTGTTAATACTGTGAGGTTATTTCCTGTTTTATTGTAAATTTTCCCATTT ATTTGCCCATAAACTAAAATATGGTTGATATTAGGAATTTTAAACAAATGTTGAAACTTTGCTGACCAGA ATGCAACCACTTTACCAAGACACAGGTACTGAGGGCTCTGGTCTATCCTGAAATGTCTGATTCTGTGCAC AGTTCCTTTACCCTTAAAAAAAAAAAAAAGAAAAGACTGGACATGTCTCTTTTTTTGCTGTTAATATTTG AAGGTCCAAGGATCTGAGTGAAAATACATTCTTGTGTTTGATCTTATAGCCAAGGCAAATTAGAAACAAA AATAGTGCCAATATTTTGAAATCTAGACCCAAGATTTCAGCCTGCTGTGTTTGGAATAAATATGAATTTT TAAAGATGTCTCCTACAGTATTTTCCTTTTGGCTACTTCTGTCTTCCTGAGAGGTACTTGTCCTCATCTA GGGATTAGCACAGGACTGCTGAGTTTGCTATTCTTAAGTCACTGGGTGACAATTTTTACCCCCTCCTTTC CTTACCAGTACTACTGCTGTTTATATTGCCTGGCTAGAGACTGGTTTATGCATCTTTACAAATGATGTCT ACCATGTAGTTGCCTCGTTAACAGTTTTATGTTGATTAAAGATGATTCTTACGTGTGGGACATCAAAATG ATAGCTTGCTTTTATCTTTCAGTTCTCATTTTCTTTTAAGGTCACCTTTCTGCAGTACAGCTTGCTTTAC TCTTTTCTCCTCATGGAGAACATGGTGTCTCCCGAAGGCCGCCTTTACGCCTGCAAAGGGCTTTGGTGGA AGAAATGGTTGGTAGACTTCCAAATCTTTGAAATGAATGGGAGCTGTTTACTTATGAATAGCTTTGGCCA GAAACTCCTCCCGAAGGTGACTTGATGTTTCCCTAACACCATTTACTTGGAATCAGAATTTTTGAACTAA TAAGCTTTAACAATGTTTGTCCCGGTCTCACCTGAGTGATGCTGTGTTTTAGATAAGCAGCTAGTTAGTT CTTGACTCAGTGCTCGGTTCTCTCTCCACCGGACCAACTGTTGTAACTAAGCGTGCTGTACTTTTCTTTA GAAATAGAGTTCTATCTGTATTCAGGATTATACTTGAAAAAATATGCCATGTTCTGATTAATAACCATCA AAGTATTCAGATTGCTTAAAGGAATTCAAGTGCAACCTGCATTCACCCCTTCTAAAACTTAATTCATAAA TACCTTTCTATAAAGCTGTGTGTAGCAAGAATGCATTGTATTTAGTTCTATGCTGGCAGGAACAGAATGG AGCACAACAAAGTACACAGCCTTACTTACGAGAGCCTTACAAAGTTACTAAATGAAGACATTGAGCTGGC TATCTAAATTTACTTTATGCTCTTTGTTTTATTGAGAATCTCTATTTAAAAAAAATCAACAAATGACAGG GCCTAGCTGTGTAAATGACCTTGCAAAATATGTTAATTTTTTTGTAAAAAAAGGATTATTTTCACATTAA AGTGAAGCCTCTTTCGCAAGTTCAGAAATCTATGGGAAAGCAGTTTTTAATCATATTTTATGTCCTATAC CTTTTTTTCTTAATAAAATGGTTTACAAAAAGAATGTAAACAATTTATGATCTGGCAGTTACACTAAGGG TTCCCAGAGAGTTGGTGGTACTGAGTAAAAAACCATTCAGGCAACTTGAGCAGACAACTGTTGTCAGTAA CATTCCTTGTGTGCGCCATTAAGCACCTCCAGATGAATGAGGGACAGTCACTTAATTTTTAAATTGTATT CGGAATAATTACTGCTGTGTACTAAGAACTTGACCCAAATAAAAATCACACGAAGTATAAAAAAAAAAAA AAAAA |
| Restriction Sites | AscI-NotI |
| ACCN | NM_198127 |
| Insert Size | 1341 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC056345, AAH56345 |
| RefSeq Size | 5605 bp |
| RefSeq ORF | 1341 bp |
| Locus ID | 329165 |
| UniProt ID | P62484 |
| Gene Summary | Regulator of actin cytoskeleton dynamics underlying cell motility and adhesion. Functions as a component of the WAVE complex, which activates actin nucleating machinery Arp2/3 to drive lamellipodia formation (By similarity). Acts as regulator and substrate of nonreceptor tyrosine kinases ABL1 and ABL2 involved in processes linked to cell growth and differentiation. Positively regulates ABL1-mediated phosphorylation of ENAH, which is required for proper polymerization of nucleated actin filaments at the leading edge (By similarity). Contributes to the regulation of actin assembly at the tips of neuron projections. In particular, controls dendritic spine morphogenesis and may promote dendritic spine specification toward large mushroom-type spines known as repositories of memory in the brain (PubMed:15572692). In hippocampal neurons, may mediate actin-dependent BDNF-NTRK2 early endocytic trafficking that triggers dendrite outgrowth (PubMed:27605705). Participates in ocular lens morphogenesis, likely by regulating lamellipodia-driven adherens junction formation at the epithelial cell-secondary lens fiber interface (PubMed:15572692). Also required for nascent adherens junction assembly in epithelial cells (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (3) has multiple differences in the coding region but maintains the reading frame, compared to variant 1. This variant encodes isoform 3, which is shorter than isoform 1. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG207119 | Abi2 (tGFP-tagged) - Mouse abl-interactor 2 (Abi2) |
CNY 4,370.00 |
|
| MR207119 | Abi2 (Myc-DDK-tagged) - Mouse abl-interactor 2 (Abi2), transcript variant 3 |
CNY 3,656.00 |
|
| MR207119L3 | Lenti ORF clone of Abi2 (Myc-DDK-tagged) - Mouse abl-interactor 2 (Abi2), transcript variant 3 |
CNY 5,890.00 |
|
| MR207119L4 | Lenti ORF clone of Abi2 (mGFP-tagged) - Mouse abl-interactor 2 (Abi2), transcript variant 3 |
CNY 5,890.00 |
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