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Spag5 (NM_017407) Mouse Untagged Clone
CAT＃: MC202063
Spag5 (untagged) - Mouse sperm associated antigen 5 (Spag5), (10ug)
CNY 8,120.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AI874642; D11Bhm180e; Deepest; MAP126; Mastrin; S17 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC052672 sequence for NM_017407
AAGAGGTAATCCGGTTAAGTGATCGAGTTGAAAATGTGGAGGGTGAAAACACTGAATCTCGGTTTGTCGC CTTCGCCCCAAAAGGGGAAGCCAGCTATGAGTACTCCTCTCCGAGAGCTTAAACTACAGCCCGAGGCCCT CGCCGATTCAGGGAAAGGTCCCTCTATGATCTCCGCGCTGACCCCATACCTGTGCAGGCTGGAGCTGAAG GAAAGATGCAACAACTCATCTCCAGTGGATTTTATCAATACTGAGAACAACTTCCTTTCAGAACAGTTCA GCCATCCTTCAACGCACATAGAAGCTTGCCAGCGTGAATCCGATCCAACTCCTGAAAGCAACTCTCTTTT CCATACTTTGGAGGAAGCAATAGAAACAGTGGATGACTTTGTCGTGGACCCAAGAGATGATAGTATAGTG GAGTCCATGGTTCTTCTGCCCTTTTCATTAGGGCAGCAGCAAGACCTGATGCTCCAGGCTCACTTAGATA CCACAGCAGAGAGAACTAAAAGCTCTCTAAATGAATCTTTGGGGCTAGAAGATCTGGTGGGGAAGGAGGT GGCACCTTGTGTGGAAGACAGCCTAACAGAAATTGTTGCTATTAGGCCCGAGCAACCTACATTTCAGGAC CCTCCGTTAGGACCCAGTGACACTGAAGATGCACCTGTGGACTTAGTTCCTTCTGAAAATGTCCTGAATT TCTCTCTGGCTCGTCTTTCTCCTTCAGCTGTCCTGGCCCAGGATTTCTCTGTCGATCATGTCGATCCAGG GGAGGAAACCGTAGAGAACAGAGTCCTACAGGAAATGGAAACGAGCTTCCCCACATTCCCTGAGGAGGCC GAATTGGGAGACCAAGCACCTGCTGCAAATGCAGAAGCCGTCTCACCCTTGTACCTGACATCAAGTCTAG TGGAGATGGGGCCCCGGGAAGCCCCAGGCCCAACAGTAGAAGACGCCAGTAGGATTCCTGGCCTTGAGTC AGAGACTTGGATGTCCCCATTGGCCTGGCTAGAAAAGGGTGTGAATACATCGGTCATGCTACAAAACCTC CGCCAGAGCTTATCCTTTTCTTCTGTGCTTCAGGATGCTGCCGTTGGCAACACACCCCTCGCCACGTGTT CTGTGGGCACTTCCTTTACTCCTCCAGCACCACTGGAGGTAGGCACCAAGGACAGTACTTCAGAGACAGA GCGCCTCCTCTTGGGCTGCCGTCCTCCAGATCTGGCTACCTTGTCCCGACACGACTTGGAAGAGAACCTG TTGAACTCTCTTGTCTTGCTGGAAGTTCTTTCCCACCAGCTACAAGCCTGGAAGAGCCAGTTGACTGTCC CTCACCGGGAAGCTCGAGACAGTAGTACACAGACTGACAGCTCTCCTTGTGGGGTCACTAAGACACCTAA ACATCTTCAGGACAGCAAGGAGATTAGACAGGCTCTACTGCAAGCCAGGAATGTCATGCAATCATGGGGT CTAGTCTCTGGAGACCTGTTGTCCTTGCTTCACCTGTCCCTAACACACGTGCAAGAAGGCAGAGTGACAG TGAGTCAGGAGTCTCAGCGGTCAAAAACCCTGGTTTCCTCCTGTTCTCGTGTGCTGAAGAAATTGAAGGC AAAGCTGCAGAGCCTCAAAACAGAATGTGAGGAGGCAAGGCACAGCAAGGAAATGGCCCTTAAAGGCAAG GCTGCGGCAGAGGCAGTACTGGAGGCTTTCCGTGCACATGCCAGCCAGCGCATCAGCCAACTGGAACAGG GTCTCACATCTATGCAGGAATTCAGAGGCCTTCTACAGGAGGCACAGACCCAACTGATAGGGCTTCACAC AGAACAAAAGGAGCTGGCTCAGCAGACAGTGAGTCTGAGTTCTGCCTTGCAGCAGGACTGGACATCAGTC CAATTGAATTATGGAATATGGGCAGCTTTGCTGAGTTGGTCTCGAGAACTCACCAAGAAACTCACAGCCA AGAGCCGGCAGGCCCTTCAGGAACGTGATGCTGCAATTGAAGAAAAGAAGCAGGTTGTGAAGGAAGTGGA ACAAGTCTCTGCCCATTTAGAGGACTGTAAAGGTCAAATCGAACAACTGAAGTTGGAAAATAGTCGCCTT ACTGCAGATCTCTCGGCTCAGCTGCAGATTCTGACTAGCACAGAGAGTCAGCTAAAGGAAGTACGGAGTC AGCATTCCCGCTGTGTCCAGGACCTGGCCGTGAAGGATGAATTGCTGTGTCAACTTACCCAGAGCAACAA GGAGCAGGCTACTCAATGGCAAAAGGAAGAAATGGAACTGAAACACATACAAGCAGAACTGCTACAGCAG CAGGCTGTGTTGGCTAAGGAGGTCCAGGACCTGAGGGAGACTGTGGAGTTTATAGATGAAGAAAGTCAAG TTGCTCACCGGGAGCTGGGCCAGATTGAGAGTCAGTTGAAAGTCACGCTAGAGTTACTGCGGGAGCGCAG CCTGCAGTGTGAGACCCTCAGGGACACTGTGGACAGCCTGAGGGCTGAGCTGGCCAGCACTGAAGCAAAG CATGAGAAACAGGCCCTAGAGAAGACACACCAGCATTCTCAAGAGCTGCGGCTACTGGCTGAGCAGCTGC AGAGTCTCACCCTCTTCTTACAGGCAAAACTCAAGGAGAACAAGGCTGAATCAGAGATCATTCTGCCCAG CACAGGCTCTGCTCCAGCCCAGGAACACCCTCTGTCCAATGACAGCAGCATCTCAGAACAGACCCCGACA GCAGCAGTAGATGAAGTGCCAGAACCAGCTCCTGTGCCATTGCTTGGAAGTGTTAAGAGTGCTTTCACCC GAGTAGCCTCAATGGCTTCCTTTCAGCCTACAGAGACCCCAGACTTGGAGAAGAGCCTGGCAGAAATGAG TACTGTGTTACAAGAGCTTAAGAGCCTGTGTTCCCTGCTGCAAGAGTCTAAAGAGGAGGCCACTGGGGTC CTGCAGAGGGAAATCTGTGAACTACACTCGAGACTACAGGCCCAAGAAGAAGAGCATCAGGAAGCCCTGA AGGCAAAGGAAGCAGACATGGAGAAGCTGAACCAGGCCTTGTGCTTGCTCCGCAAGAATGAGAAGGAGCT CCTGGAAGTGATACAGAAGCAGAACGAGAAGATCCTGGGGCAAATAGACAAGAGCGGCCAGCTCATAAAC CTCAGAGAGGAGGTGACCCAGCTCACACAGTCACTTCGGCGTGCAGAGACAGAGACTAAAGTGCTCCAGG AAGCCCTGGAAGGCCAGCTAGATCCCAGCTGCCAGCTGATGGCTACTAACTGGATCCAGGAAAAAGTGTT TCTCTCACAGGAGGTGAGCAAGCTGAGGGTTATGTTCCTGGAGATGAAAACTGAGAAGGAACAGCTGATG GACAAGTATCTGAGCCATAGGCACATCCTGGAGGAGAACCTTCGGCGCTCTGACACAGAGTTAAAGAAAC TCGATGACACAATTCAGCATGTCTATGAGACTCTGTTGTCTATCCCAGAGACTATGAAGAGTTGCAAGGA GTTACAAGGATTGCTAGAATTTCTGAGCTAAGAAACTGAAAATATTGGAACGCAGTGGTGTGCACCTGTA GTTCCAGCTGCTCCAGACGCCAAAGTTGGAGTGCTGCCAAATCCCAGGAATTTGGGAACCTAACACAGAC AACACAGCAAAAACCCTGAAAAATGAATTCCACTCCACTCCAGTTTCCTTCAGGGCTCTTTATCCCAACC CTTATCCCAATAATAAGACCAATTGGCATAGAGCCGACCATGTTTTATGTTATTTAAATAAAGTGTATTT AATGTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAG |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_017407 |
| Insert Size | 3498 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC052672, AAH52672 |
| RefSeq Size | 3818 bp |
| RefSeq ORF | 3498 bp |
| Locus ID | 54141 |
| UniProt ID | Q7TME2 |
| Gene Summary | Essential component of the mitotic spindle required for normal chromosome segregation and progression into anaphase. Required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. In complex with SKAP, promotes stable microtubule-kinetochore attachments. May contribute to the regulation of separase activity. May regulate AURKA localization to mitotic spindle, but not to centrosomes and CCNB1 localization to both mitotic spindle and centrosomes. Involved in centriole duplication. Required for CDK5RAP22, CEP152, WDR62 and CEP63 centrosomal localization and promotes the centrosomal localization of CDK2. In non-mitotic cells, upon stress induction, inhibits mammalian target of rapamycin complex 1 (mTORC1) association and recruits the mTORC1 component RPTOR to stress granules (SGs), thereby preventing mTORC1 hyperactivation-induced apoptosis. May enhance GSK3B-mediated phosphorylation of other substrates, such as MAPT/TAU (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG211734 | Spag5 (tGFP-tagged) - Mouse sperm associated antigen 5 (Spag5) |
CNY 9,220.00 |
|
| MR211734 | Spag5 (Myc-DDK-tagged) - Mouse sperm associated antigen 5 (Spag5) |
CNY 8,112.00 |
|
| MR211734L3 | Lenti ORF clone of Spag5 (Myc-DDK-tagged) - Mouse sperm associated antigen 5 (Spag5) |
CNY 10,260.00 |
|
| MR211734L4 | Lenti ORF clone of Spag5 (mGFP-tagged) - Mouse sperm associated antigen 5 (Spag5) |
CNY 10,260.00 |
