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Amotl2 (NM_019764) Mouse Untagged Clone
CAT＃: MC201937
Amotl2 (untagged) - Mouse angiomotin-like 2 (Amotl2), (10ug)
CNY 5,664.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AW549739; C79691; Lccp; MASCOT; mKIAA0989 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC027824 sequence for NM_019764
CCACGCGTCCGGCTGACTGTACCTAAGCCGAACCGGGTCTGCGTGCGCCGGCAGCCGCGGGCCGCAGCGG TGCTCTGAGACCAGGTGCCTGCTGGCCATTGTCTAGGCAGGTGTGTGCAAGCCAGAGAAGCATGAGGACA CTGGAAGACTCCTCAGGGACAGTCCTGCACCGTCTCATCCAAGAGCAGCTGCGCTACGGCAACCTGACAG AGACTCGCACTCTGCTGGCTATCCAGCAGCAGGCCCTGCGGGGTGGGGCTGGAGCTGGGGGCACGGGGAG CCCCCAGGCTTCCTTGGAGATCGGAGCACCCGAGGACAGTCAGGTGCTGCAGCAAGCCACCAGGCAGGAG CCCCAGGGCCAGGAGCATCAGGGTGGAGAGACCCACCTGGCAGAGAACAGGCTGTACCGGCTGTGCCCAC AGCCCAGCAAAGGAGAAGAGTTGCCCACCTATGAGGAGGCCAAAGCCCATTCGCAGTACTACGCAGCGCA GCAGGCAGGGTCCCGGCCGCATGTTGGGGACCGGGATCCTAGAGGAGGGGTGTCCGGAGGCGGCCGGCGA CAGGATGAAGCTCTTCGAGAGCTGAGGCATGGCCATGTGCGCTCCTTGAGTGAACGGCTTCTGCAACTGT CCCTGGAAAGAAACGGTGCTCGGGTCCCCAGCCACATGAGCTCTTCCCACAGCTTCCCTCAGCTGGCCCG CAGCCAGCAGGGCCCCCAACCCCGAGGGCCCCCAGCTGAGGGCCCAGAGCCCCGCGGGCCACCACCTCAG TACCCACACGCTGTAATGGCTCAGGAGACTGCGGCTGTCACTGACCCAAGATACCGACCCCGAAGCAGCC CACACTTCCAGCATGCCGAAGTCAGGATCCTGCAGGCCCAGGTACCACCGGTGTTCCTCCAGCAGCAGCA GTACCAGTACCTGCCGCAGCCCCAGGAGCACTCTCCACCCCTCCACCCGGCAGCTCTGGGCCATGGACCC CCAAGCTCCTTTGGTCCACCTGCAGTGGAGGGACCACCCAGTGCCCAGGCCACCTTGGGCAGTGCCCACC TGGCCCAGATGGAGACTGTACTGAGGGAGAATGCCAGGCTGCAGAGGGACAATGAGCGATTGCAGAGAGA GCTGGAGAGCACTTCAGAGAAGGCTGGCCGCATAGAAAAGCTGGAAAATGAAATCCAGCGGCTCTCTGAG GCCCACGAGAGCCTGATGAGGACCTCTTCCAAGCGTGAGGCCCTGGAGAAGACCATGAGGAACAAGATGG ACGGTGAGATGAGACGGTTGCAGGACTTCAACCGAGACCTTAGAGAGAGATTGGAATCGGCAAACCGCCA CCTGGCAAGCAAGACCCAGGAAGCCCAGGCGGGCAGTCAGGACATGGTGGCGAAACTGCTTGCCCAGAGC TATGAGCAGCAACAGGAACAGGAGAAGCTGGAGCGGGAGATGGCACTGCTGCGTGGTGCCATCGAGGACC AGCGGCGACATGCTGAACTGCTGGAGCAGGCTCTGGGCAATGCACAAAGCCGTGCCGCCCGGGCTGAAGA GGAGCTACGCAAAAAGCAGGCCTATGTGGAGAAGGTGGAGCGGCTGCAGCAGGCACTGGGGCAGTTGCAG GCTGCCTGTGAAAAGCGAGAGCAGTTGGAGCTGCGTCTGCGCACGCGCCTGGAGCAGGAACTCAAAGCCT TGCGTGCACAGCAGAGGCAGACAGGCACCCTCGCAGGTGGTGGCGGCAGCCATGGTGGGTCCGCCGAGCT CAGTGCCCTGCGGCTGTCTGAACAGCTGCGGGAGAAGGAGGAACAGATCCTGGCTCTAGAGGCGGACATG ACCAAGTGGGAACAGAAGTATTTGGAAGAACGGGCTATGAGGCAGTTCGCCATGGACGCGGCTGCCACTG CGGCTGCCCAGCGCGATACCACTCTCATCCGGCACTCCCCCCAGCCCTCGCCCAGCAGCAGTTTCAACGA GGGCCTGCTGCCAGGCAACCACAGGCACCAGGAGATGGAGAGCAGATTGAAGGTGCTCCATGCTCAGATC CTAGAGAAGGATGCGGTGATCAAGGTCCTTCAGCAGCGCTCCAGGAAAGACCCTGGCAAGGCCACCCAGG GCACCCTACGGCCTGCCAAGTCGGTGCCGTCCATCTTCGCGGCTGCAGTGGGAACTCAGGGCTGGCAAGG GCTCGTATCCAGTGAGCGGCAAACTGATGCACGGCCAGCGGGAGACCGGGTCCCAGCAGAGGAGCCTCCG GCCACAGCTCCTCTCCCTGCCCACACCAAACATGGCAGCAGAGACGGGAGCACCCAGACGGATGGCCCTG CAGACAACACCTCTGCCTGCTTGGCCTCAGAACCCGATGGCCTCCTGGGGTGCAACAGTAGCCAGAGGAC ACCCTCTCTGGACTCTATAGCTGCAACCAGAGTCCAGGATCTGTCAGACATGGTAGAAATACTGATCTGA AGGAAGGAGGCAGTGCCTTGGAGACCCCGAAGCCTGGCTCCCTCCTGGCATTCCGGCAGTTGTCTTCAAA TGCTGTGCCTCACATCCTCCGACCAGTGATGCCTTGGTGCATGGGGCTCAGAGAGGAGCACCCCAGGGGA GCTAGCTAGAAAAGCCTGCACCCCCTAGAAGACTGCTTTTTGGCCTATATTTCTCCTATGACAATGAGGA AGGAAAAGCCAGACATCACCTGCAGCCGGAGGCCTGTTGCTGGGGCAGAAAGGAGCTAAGCCCCCTCCGT CCTGCCTGAAGGAAACAGCGGATTCTGACGCCCAAGAATGGCTGGGCACCAGCCGAGCGGTCTGCAGGGA TCGTTAGGCCAGCTATGGTGTTCTGTGGCTAAGCATGGCTCCAGCCAACACTATCTGCTCTTCAGTCCCT GACTGACTTCCTCAGATCACTAAGACTTGAATCCTTGGGAGGTGGGGGACGATGGGAGTGTGAGTCTTTC GGGAGCCACCAGCATGTCCCCTTGGAGTAGGTTAGAGGTCACTTGAGAGGCCCCGCAGAGCAGTGTGTTT TGTATATAATTCTTTTTCCTTGGGAACAGAAGACTAAGCGTGCCGGTTCAGAGTCTCCTCCAGGGCTGTG CTGCCTGCCCCTGCTGCCACAGTTCTTGAAACATGTGACAGGTCTACCAGATGTTCCTCTGCCTGCAGTT CCTGGCTGTGGATTTTGATACTGGTTGGCTTTCCTCTGCTTTTTAAATCCCTGTGTTTCGTGCCCATGGG ATTCTTATCACCAGCCTTTGTGAATGGCTCCACAGCTCCTATCCCTGGGACATCCTGTCAGTTTGGTTAT AAACTGAGCCAGATGTGATGAGCCACCACAAGCGGACATCTGTCATGCCCAGCACCAGGTTCTCTTTGAA GAAACTGGAGAAATTGTTCTCATAAATGTATTCGTTCCCACCAGCAGGGACTGGGAGAGGGAGCTATGTT GTTAAAACGAATCAGTGAACTTAAAGAAAAGTCCTCATTATGGTGCCCCCACCACAGAATGGCACCCTTA GAGGCTGGCTCCTCAAGTTTTGGTGCCCCAGCCCTGAAGCAGGGCCAGCTACTTGGAATTAGGTGAACTA CCCCCACGTGGCAGACCACCAGCAGCAGTGACTTTGACTTCTGGTCTTAAAGCAACCCCCATTCAGCTCA AAAAGCGATTGGTGGATTTCAGATCTTTTGTGTTTTTCTCCTCTGGTTGTTTTGTTTGTTTTTCTTTCAC TGTTTGAAGTTCTGTCTGTTGTTTGTTCCATTCCCATAGTTCTCTCTGCATTTCCTTTTTAAACATTTGC ATTTGCTGGGCAATTGCGTATTTTTTTAATTCCCTTTCCCCTATGTAAAGCTGAGAAATACATCTGGTTC ATGTACGTTGTTTACAAAGATAAAAGTTTTAAAAAAAAAAGGAGGGGGAAAAGAAGGCAAAAAAATATTG TGAAAGGAAAAAAAAAACAACTTAATATATTTTGGATTAATATTTGGTATTTCTTTTAAAGTATTTTTTT TGTGCTGTGAACGTTTTCTGCCAAAGACCATGACGTGTGTCTGTGTGTTTAAGTTATCATGAATATTTAA AGTGTAAACATGGCTGTTTTGTTACGCCACTCTGTACCAGGATTGCTGCTGCATTCCGCCAGGTATGACA GTATTTTAATAAAAAAAGAGCTTATAAGGAGAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_019764 |
| Insert Size | 2319 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | BC027824, AAH27824 |
| RefSeq Size | 4185 bp |
| RefSeq ORF | 2319 bp |
| Locus ID | 56332 |
| UniProt ID | Q8K371 |
| Gene Summary | Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. Participates in angiogenesis. May play a role in the polarity, proliferation and migration of endothelial cells. Selectively promotes FGF-induced MAPK activation through SRC (By similarity).[UniProtKB/Swiss-Prot Function] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Phosphorylation of the Hippo Pathway Component AMOTL2 by mTORC2 Promotes YAP Signaling Resulting in Enhanced Glioblastoma Growth and Invasiveness
,Artinian, N;Cloninger, C;Holmes, B;Benavides-Serrato, A;Bashir, T;Gera, J;,
J. Biol. Chem.
,PubMed ID 25998128
[AMOTL2]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG207385 | Amotl2 (tGFP-tagged) - Mouse angiomotin like 2 (Amotl2) |
CNY 6,370.00 |
|
| MR207385 | Amotl2 (Myc-DDK-tagged) - Mouse angiomotin-like 2 (Amotl2) |
CNY 5,664.00 |
|
| MR207385L3 | Lenti ORF clone of Amotl2 (Myc-DDK-tagged) - Mouse angiomotin-like 2 (Amotl2) |
CNY 7,700.00 |
|
| MR207385L4 | Lenti ORF clone of Amotl2 (mGFP-tagged) - Mouse angiomotin-like 2 (Amotl2) |
CNY 7,700.00 |
