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Lrrc8c (NM_133897) Mouse Untagged Clone
CAT＃: MC201792
Lrrc8c (untagged) - Mouse leucine rich repeat containing 8 family, member C (Lrrc8c), (10ug)
CNY 5,888.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AD158; AI326115; E430036I04Rik; fad158 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC026572 sequence for NM_133897
GCCCGCGAAGAAGACGAGGACCGAGGCGCCGCCGCGGCCGTGGCCGCAGCACTCTGAGCGCGACAAGCCA TGAGCAGCGACGCCGCGGTCGCTTGCCGCCGCTGAGCCCAACCCGGACACAGCTCGCCGCGCCCTGGCAT CCTTTTCTGCGGATACCCTCGCCCCCAGAGATTAATGTGGCTGCTTATGACTAAGGATTCTGGGACCACA GATGTTCAGAGAAGTAACATATACATATAAGAAACATGATTCCGGTGACCGAGTTCCGGCAGTTCTCCGA GCAGCAGCCCGCCTTCCGGGTGCTGAAGCCGTGGTGGGATGTGTTCACGGATTACCTCTCGGTGGCCATG CTGATGATCGGAGTGTTTGGATGTACTTTACAGGTCATGCAAGACAAGATCATCTGCCTTCCAAAAAGAG TGCAGCCTGCTCAGAACCACTCTTCCGTTCCCAATGTCTCCCAGGCAGTTATCAGTACCACTCCGCTGCC CCCACCTAAACCCTCACCGACCAACCCCGCGACCGTGGAGATGAAGGGACTGAAGACAGACCTGGACCTT CAGCAGTACAGTTTCATCAACCAGATGTGCTACGAGCGAGCCCTCCACTGGTATGCCAAGTACTTCCCAT ACCTGGTGCTCATCCACACCCTGGTCTTCATGCTCTGTAGCAACTTCTGGTTCAAATTCCCCGGATCCAG TTCCAAAATAGAACATTTCATCTCCATCCTGGGGAAGTGCTTTGACTCCCCGTGGACCACACGGGCTCTC TCCGAAGTGTCCGGAGAGGACTCCGAAGAGAAGGACAACAGAAAAAACAACATGAACAGGTCCGGCACCA TCCAGTCTGGTCCCGAGGGCAACCTGGTGAGGTCCCAGTCTCTCAAGTCAATTCCTGAAAAGTTCGTGGT TGACAAATCTGCTGCGGGGGCTCTGGACAAGAAGGAAGGTGAGCAGGCCAAGGCCTTGTTTGAGAAGGTG AAGAAGTTCAGACTGCATGTGGAAGAAGGTGATATCCTGTACGCCATGTACGTGCGACAGACTGTGCTGA AGGTCATCAAATTCCTAATCATCATTGCCTACAACAGTGCCCTGGTTTCCAAAGTCCAGTTCACAGTGGA CTGTAATGTGGACATCCAGGACATGACGGGCTATAAGAACTTTTCTTGCAATCACACCATGGCTCATTTG TTCTCTAAGCTCTCCTTTTGCTACCTGTGCTTTGTAAGCATCTATGGCCTGACGTGCCTTTACACCTTAT ACTGGCTGTTCTACCGTTCTCTGAGGGAATATTCGTTCGAGTATGTCCGGCAGGAGACGGGAATCGATGA CATTCCGGATGTGAAAAATGACTTTGCTTTCATGCTCCATATGATAGACCAGTATGACCCTCTCTATTCC AAGCGGTTTGCAGTGTTCCTGTCTGAAGTCAGCGAGAACAAGTTAAAACAACTCAATTTAAATAACGAGT GGACCCCGGACAAACTGCGGCAGAAGCTGCAGACAAATGCCCACAACCGCCTGGAGCTGCCGCTGATCAT GCTGTCTGGCCTCCCGGACACCGTGTTTGAAATCACAGAGTTGCAGTCTCTGAAGCTGGAGATCATTAAG AATGTCATGATCCCCGCCACCATCGCCCAGCTAGACAACCTGCAGGAGCTCTGTCTGCACCAGTGCTCCG TCAAGATCCACAGCGCCGCGCTCTCCTTCCTGAAGGAGAATCTCAAGGTCCTGAGTGTCAAGTTTGATGA CATGAGGGAGCTGCCCCCCTGGATGTACGGCCTCCGGAACCTAGAAGAGCTCTATCTGGTTGGCTCTCTG AGTCACGACATCTCCAAAAATGTCACCCTGGAGTCTCTGAGGGACCTCAAAAGCCTTAAAATCCTTTCCA TCAAGAGCAACGTCTCCAAGATCCCTCAGGCCGTGGTGGATGTGTCCAGCCACCTCCAGAAGATGTGCGT CCACAATGATGGCACCAAACTGGTGATGCTCAACAACCTGAAGAAGATGACCAACCTGACGGAGCTGGAG CTGGTCCACTGCGACCTGGAACGCATCCCCCACGCCGTGTTCAGCCTGCTCAGTCTCCAGGAGCTGGACC TGAAGGAGAACAACCTCAAGTCCATAGAGGAGATCGTGAGCTTCCAGCACTTGAGAAAGCTGACCGTGCT CAAACTGTGGTATAACAGCATCGCTTACATTCCAGAGCACATCAAGAAACTGACCAGCCTGGAGAGACTG TTTTTCAGCCACAATAAGGTAGAGGTGCTTCCCTCCCACCTCTTCCTGTGCAACAAAATCAGATACCTGG ACTTGTCCTATAACGACATCCGCTTCATCCCGCCCGAAATCGGAGTTCTGCAAAGTTTACAGTATTTTTC CATCACTTGTAACAAAGTGGAGAGCCTCCCAGATGAACTCTACTTCTGCAAGAAACTTAAAACTTTGAAG ATTGGGAAAAACAGCCTCTCCGTACTTTCACCAAAAATTGGAAATCTACTATTTCTTTCCTACTTAGACA TCAAAGGCAATCACTTTGAAGTCCTCCCTCCCGAGCTGGGAGACTGCCGGGCTCTGAAGCGAGCCAGGCT AGTTGTGGAAGATGCTCTGTTTGAGACTCTGCCCTCAGATGTCCGGGAGCAGATGAAAGCAGACTAACTT ATTTTTCATCAGAGTATGACTGAAACATGCTTCTACCAAATACAATATAAAGAATTAGGTAGTCCTAATG CCTTTCCTATATTATATTTTTTTCCTTTTCCACACAAGACAACATGTACACAAAGATTGAGTAAGGAGTA TGTATTTTTTAATAAAAATTTAATTGTATTTTTTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAA |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_133897 |
| Insert Size | 2412 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC026572, AAH26572 |
| RefSeq Size | 2874 bp |
| RefSeq ORF | 2412 bp |
| Locus ID | 100604 |
| UniProt ID | Q8R502 |
| Gene Summary | Non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes (PubMed:29769723). The VRAC channel conducts iodide better than chloride and can also conduct organic osmolytes like taurine. Plays a redundant role in the efflux of amino acids, such as aspartate and glutamate, in response to osmotic stress. Channel activity requires LRRC8A plus at least one other family member (LRRC8B, LRRC8C, LRRC8D or LRRC8E); channel characteristics depend on the precise subunit composition (By similarity). May play a role in adipogenesis (PubMed:15564382, PubMed:15184384, PubMed:21804215).[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG210745 | Lrrc8c (tGFP-tagged) - Mouse leucine rich repeat containing 8 family, member C (Lrrc8c) |
CNY 6,370.00 |
|
| MR210745 | Lrrc8c (Myc-DDK-tagged) - Mouse leucine rich repeat containing 8 family, member C (Lrrc8c) |
CNY 5,880.00 |
|
| MR210745L3 | Lenti ORF clone of Lrrc8c (Myc-DDK-tagged) - Mouse leucine rich repeat containing 8 family, member C (Lrrc8c) |
CNY 7,700.00 |
|
| MR210745L4 | Lenti ORF clone of Lrrc8c (mGFP-tagged) - Mouse leucine rich repeat containing 8 family, member C (Lrrc8c) |
CNY 7,700.00 |
