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Plscr3 (NM_023564) Mouse Untagged Clone
CAT＃: MC201608
Plscr3 (untagged) - Mouse phospholipid scramblase 3 (Plscr3), transcript variant 1, (10ug)
CN¥ 2,400.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 2210403O21Rik; 2610037N06Rik; ESTM3; X83310 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC020143 sequence for NM_023564
GGGGCTTCAGGTGCCGCCCTAGAGACCCTGGGCCCGTACTGGGCGCAGCTACCTCTTCGCCTCTGCCTGT CCGTCTTTGTTTCTGTGTCTGTCTAGCTGTTCCCGAGCTTGTCCCACTCCAGAACTAAGTCTCCCCTACG CCAAAAGCCCAAGACTCCCCTCCTGATTCCCATGGCAGGCTACTTGCCCCCCAAAGGCTATGCCCCTTCA CCCCCACCTCCCTACCCCGTGCCATCTGGGTATCCAGAGCCGGTGGCTCTGCATCCTGGACCGGGACAAG CTCCAGTGCCCACCCAGGTGCCTGCCCCTGCTCCCGGCTTCGCTCTCTTCCCCTCGCCAGGCCCAGTGGC TCCAGGGCCTCCTGCTCCTTTCGTGCCATTGCCAGGGGTGCCTCCTGGCCTCGAATTCCTAGTGCAGATT GATCAAATCTTGATTCATCAGAAGGCTGAACGAGTGGAAACGTTCCTAGGCTGGGAGACCTGTAATATGT ATGAACTTCGCTCCGGAACCGGACAGCAACTGGGTCAGGCAGCTGAAGAGAGCAACTGTTGTGCCCGCCT GTGCTGTGGTGCCCGCCGACCATTTCGAATCCGCCTAGCGGACCCTGGGGACCGCGAGGTGCTCCGGCTC CTCCGCCCACTTCATTGTGGCTGCAGCTGCTGCCCCTGTGGTCTTCAGGAGATGGAAGTCCAGGCTCCAC CTGGCACCACCATTGGCCATGTGCTACAGACCTGGCATCCCTTCCTTCCTAAGTTTTCCATCCTGGATGC TGATCGCCAACCTGTTCTACGAGTTGTAGGGCCTTGCTGGACTTGTGGCTGTGGTACAGACACCAACTTT GAGGTGAAGACTAAGGATGAATCGCGAAGTGTGGGCCGCATCAGCAAGCAGTGGGGAGGGCTGCTCCGAG AAGCCCTCACAGACGCCGATGACTTTGGCCTCCAATTCCCAGTCGATCTAGATGTGAAAGTGAAGGCCGT ACTGCTGGGAGCCACGTTCCTCATCGATTATATGTTCTTCGAGAAGAGAGGAGGCGCAGGACCCTCTGCC ATCACCAGTTAGAAGCCACCTCAGGATGAGGAGACCCATCTCCTTGACCAGAATTTAAGATGGTCAGCTG CCCTGGACGTTCCCTCCTGAAGCAACCCTTTCCTTGATATACACTGCGGCGGACCGACGAGGGTGGCCGA GTGGTTTGGAGCCGTTGTGTCCCATCCCTTCCCTGCTTCTCCTGTGGCCCTGCAGAAGAGCATGTATGAG ACCTGTTCCTCCTTCTGTTCACCATCTCCAGGCAGTGCCTGTGCACACATTAGCTTTTAAACTTCCTTGC ACACTCCTTCCAGCCTTCCTCTGGGGCCTCTGCATAGGCAGGGGCATCTGGAATCCTGGACTCAAGTTTT ACCCCAGGGCTTGTGGGTAAAAGGCAAGCAGTACCAAAGATGGCAGACACCACCCTTCCCTTATGGCACT TTAGCCAATTAGTTTAGCTTCCGATTGTGGCACTCTGAGGGGATCCTTGCCTCCTCACTAATAGCTGTAG CGGTTGGGCCCCAGTGCCAACTCCCTAAGCCCCTGGGCCCTGCGGGTGCTTTCTGCAGCTTCCTGTGCCT TATTTAACCGTTAACCCCTTCCTTCCCCTACTGTAGGAAGGAGGCTGTGTCTTTGTATGTTGTACTCATA TAAACTTTGAAACTTTTTAAACAAAAAAAAAAAAAAA |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_023564 |
| Insert Size | 891 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC020143, AAH20143 |
| RefSeq Size | 1717 bp |
| RefSeq ORF | 891 bp |
| Locus ID | 70310 |
| UniProt ID | Q9JIZ9 |
| Gene Summary | May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) encodes the functional protein. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells
,Chu, CT;Ji, J;Dagda, RK;Jiang, JF;Tyurina, YY;Kapralov, AA;Tyurin, VA;Yanamala, N;Shrivastava, IH;Mohammadyani, D;Qiang Wang, KZ;Zhu, J;Klein-Seetharaman, J;Balasubramanian, K;Amoscato, AA;Borisenko, G;Huang, Z;Gusdon, AM;Cheikhi, A;Steer, EK;Wang, R;Baty, C;Watkins, S;Bahar, I;Bay?r, H;Kagan, VE;,
Nat Cell Biol. 2013 Oct;15(10):1197-205.
,PubMed ID 24036476
[Plscr3]
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