Lin7b (NM_011698) Mouse Untagged Clone

CAT#: MC201427

Lin7b (untagged) - Mouse lin-7 homolog B (C. elegans) (Lin7b), (10ug)



  "NM_011698" in other vectors (4)

CNY 2,400.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (3)
TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Mouse Untagged Clone
Tag Tag Free
Synonyms LIN-7B; MALS-2; Veli2
Vector PCMV6-Kan/Neo
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>BC031780 sequence for NM_011698
GCGGGTGGCTTGCATTAGAGGCGATATGGCTGCACTGGTGGAGCCGCTGGGGCTGGAGCGGGACGTGTCC CGGGCTGTGGAGCTGCTGGAGCGGCTGCAGCGCAGCGGAGAGCTGCCCCCGCAGAAGCTGCAGGCCCTGC AGCGGGTCCTGCAGAGTCGCTTCTGCTCCGCCATCCGCGAGGTGTATGAACAGCTCTATGACACGCTGGA CATCACTGGCAGCGCCGAGGTGCGGGCTCATGCCACAGCTAAGGCCACAGTGGCTGCTTTCACGGCCAGT GAGGGCCACGCACATCCCAGGGTCGTGGAACTACCGAAGACTGATGAGGGTTTGGGCTTCAACATCATGG GTGGCAAGGAGCAGAACTCACCCATCTATATCTCTCGAGTCATCCCTGGGGGCGTGGCTGATCGCCATGG TGGCCTCAAGAGGGGAGACCAGCTGCTGTCTGTGAATGGTGTGAGTGTGGAAGGCGAACACCATGAAAAG GCGGTGGAACTCCTGAAGGCTGCACAGGGCTCAGTGAAACTGGTGGTGCGCTACACTCCTCGGGTGCTGG AGGAGATGGAAGCCCGCTTCGAGAAGATGCGATCTGCCCGTCGGCGCCAGCAGCACCACAGCTACACGTC CTTGGAGTCTCGAGGCTGAAATCACAGACCAGGACCCTCCTTCTCCTCCCCTGTACAGTATTATTTATTG TCACTGGCTCCTTATTTAAAGATCTTTAACCCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAA
Restriction Sites RsrII-NotI     
ACCN NM_011698
Insert Size 624 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq BC031780, AAH31780
RefSeq Size 774 bp
RefSeq ORF 624 bp
Locus ID 22342
UniProt ID O88951
Gene Summary Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells. May increase the amplitude of ASIC3 acid-evoked currents by stabilizing the channel at the cell surface.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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