Chi3l1 (BC003780) Mouse Untagged Clone

Specifications

Product Data
Type	Mouse Untagged Clone
Tag	Tag Free
Synonyms	Brp39, brp-39
Vector	PCMV6-Kan/Neo
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	Fully Sequenced ORF (showhide) >BC003780 CCCTGACTAGGAAGCTGGGTACTAGGAGAAGCCATCATGCACACCTCTACTGAAGCCAGGATGGGCATGA GGGCGGCACTGACAGGCTTTGCGGTCCTGATGCTGCTCCAGAGCTGCTCTGCGTACAAGCTGGTCTGCTA CTTCACCAGCTGGTCCCAGTACCGGGAAGGCGTTGGAAGCTTCTTACCAGACGCCATCCAACCTTTCCTG TGCACCCACATCATCTACAGCTTTGCCAACATCAGCAGCGACAACATGCTTAGCACATGGGAGTGGAATG ACGAGTCGAACTATGACAAGCTGAATAAACTGAAGACCAGAAACACCAACCTGAAGACCCTCCTGTCTGT TGGAGGGTGGAAATTTGGCGAAAAAAGATTTTCCGAGATTGCCTCCAACACTGAGAGACGCACTGCTTTC GTCCGGTCGGTAGCCCCGTTCCTGCGTTCTTATGGCTTTGATGGGCTGGATCTCGCCTGGCTCTACCCTC GCTTAAGAGACAAGCAGTATTTCTCCACCCTGATCAAGGAACTGAATGCGGAATTCACAAAGGAGGTCCA GCCAGGCAGAGAGAAACTCCTGCTCAGCGCAGCTTTGTCAGCAGGAAAGGTGGCCATTGACACTGGCTAT GACATCGCCCAGATAGCCCAACACCTGGATTTTATCAATCTCATGACCTACGATTTCCATGGAGTCTGGC GCCAAATCACAGGCCACCACAGCCCCCTCTTCCAAGGCCAGAAGGACACTAGGTTTGACAGATACAGCAA TGTGAACTATGCCGTGCAGTACATGATACGTCTGGGAGCCCAGGCCAGCAAGCTACTGATGGGCATCCCC ACCTTTGGGAAGAGCTTCACTCTGGCATCTTCTGAAAATCAGTTGGGAGCTCCAATCTCAGGGGAAGGAT TACCAGGCCGGTTCACCAAGGAGGCAGGGACCCTGGCCTACTACGAGATATGCGACTTCCTCAAAGGAGC TGAAGTACATCGACTCTCCAACGAGAAGGTTCCCTTCGCTACCAAGGGCAACCAGTGGGTGGGGTATGAG GACAAGGAGAGTGTCAAAAACAAGGTTGGGTTCCTGAAGGAGAAGAAGCTGGCAGGAGCCATGGTGTGGG CACTGGATTTGGATGATTTCCAGGGCACCTGTCAGCCGAAGGAATTCTTCCCGCTCACCAACGCCATCAA GGATGCCCTGGCTTAGCTCCCCCTTTCCCATATGGTACCCCCACTCTCTGGCCAGGAGTTTAATCTCTTG CAATGTTAAGTTCCCCAACTGAGCCTCAGTTTCTCCTTCCCTTGGCACCTGTGTAAGGGGCCACAGCAGG CTCAGCTATGGAGAACAGGGAACTAGGGTAGGACGATGGTGGGGTTGTGAGAGTCACAGTGTGAGCAGAT ACACAACCCTGTTAAGGAATGCAAATTCTCAGACTCTAACCTCCCTTTACCCAGCCTGACCAAAGGACAC CACTTGGATCAAGTAGGCAAATATCTTACAGGATTGAGGGACCATACTAATTATACCCTCTGCAAAGCCC AACTTGAATCCTTCCCTTAGGAACTTAATCGTCCCACTTCCCTTTCCCTAATTCCACAGCTGTTCAATAA AGCGCCAGAACCTAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Restriction Sites	RsrII-NotI
ACCN	BC003780
Insert Size	1146 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	BC003780, AAH03780
RefSeq Size	1651 bp
RefSeq ORF	1146 bp
Locus ID	12654
Gene Summary	Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung.[UniProtKB/Swiss-Prot Function]

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