DCAMKL1 (DCLK1) (NM_004734) Human 3' UTR Clone

Specifications

Product Data
Product Name	DCAMKL1 (DCLK1) (NM_004734) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CL1; CLICK1; DCAMKL1; DCDC3A; DCLK
ACCN	NM_004734
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC222414 3’UTR clone of NM_004734 The sequence shown below is from the reference sequence of NM_004734. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TTTTCCGACGAAGACGCAACCAGGATGTGAGGAGCCGGTACAAGGCGCAGCCAGCTCCTCCCGAACTCA ACTCGGAATCGGAAGACTACTCCCCAAGCTCCTCCGAGACTGTTCGCTCCCCTAACTCGCCCTTTTAAT AAGACCCTTTTACTCAAAGTCCTAGCTTAACCCTTTGAGACTCTGAGATTTTTTTCCCCCAAATTTGTG TAAAACAGTTTCATCTGATCTATCTAGCGCTCAATGCTTGAATGGCAGAACTGAAAGTGTTTTCAGGTA TCTTTGTAGCGGTTTCCCTTTACTGAATAAGATGACACGTGGTGATTGTGAAGATGGTAATTTGCTGCT AATAGAGTCCTCAAAGGGTTAAGGCCAATTTGCAATTTTTTTTTAAACTTAGAAGCAATGAATGTTTTC ATCAGTCAAGCTAGGATCTGCAGTATGTAATATAGCACTTGTTAACCCTCTGAGTGCATAGAATTTTAT TGAGAATTCTTGTTTGGGAATTTTTCAGGCCTTTGGATGTATACACACATGTTTCTTGATTTTACTGCA GATCAAGGGGTGTTGTTAGATGCTGAAATGTCCAGAAAAGAAGGACATTTAGAATGATATCTTGTTTGT CCTTTTCTGTGGGTTTAGAACGTGGCAGGTTTATAACTTCGACACACGCACGGTTCTTTCTTCTTCACA ATCCTATTCAGAAACAGATTTTTTTTTTCATTAGAGATATGACTGTCAGTTGCAGTGAGTTCTGCATCC CAAGTGGAGGGAATTGGGTTTGTGGCAAAGAGCTTGACCCAGGAAATAGATGGTGCCCCCCAAATTGTC TCCACATGAAGATGTACTGATGACGCCCCAGAAATGCTGCTTCCATATCAGCTGCTGCTAGCGCCAGCG CAGACTCTCAGGGAGTCACCACAGCTTGTCTTGTGCTTGGTGAGTGAGGGTCTCTCTACTCAGTGTCAG ACATCTACAGGAAAGAAACAACTGGTGGAAAAGAGCAATAAATTGCCCGGTGCTCTGCAGGGCTGGAAT TTCAAACAGAAAGAGGGAATAAGATCCTGTGATTTTTCTCACCTGCTTTTCCACGCACTGTGGTCATCA CTGTGCAATCTACATCTAGTATGAAATCCACACATAGGAGAGCTGGGGCACAAGGGGACTGGAGGCAGT TGCTTTGCAAGATGGCTGAGGAGAAAGCACACTGGGAACACAATCCAGAATGTTCTAACAATAAGTTTT CAGTGAATAAACCACTGGCAAGACAATTCCATGTGCACCTTTAGGTTACCTATATAGTCTCCTAGGAAG ATCAGGATGAAAGACCTAGATGATACCCCTGAGGATAAAACCTCCATCCCCTAAAATGATTTTTTTTAA ATACCACTGTCTTTAGCTGTCCAGGAGGTCAGAGTGTTTTTTCTGTCTTTGGGCCAAGTCCTGTCTGAG ACCTGTATTTTCACTCTTGTTACCAAATCTATCTCCCTAGTGCAGTGTCTCCAGGCCTGAGTTTCTTCT GGAACAGATTCCATTTTAGAATGGGGATTCACAGGTTCTGTGCATCACCACAGTGCTCAGAGAGGATTC TCCTGGGGTGTCTTAGAGGCAGGTGCCCAACTCAAATGTATTCCCAAGGTTTGCTGGGCTCTGGGATCC ACGAGACAACCAGAGAGGGATATCTCATGAAATTTGCATCTGGTGGCTGAACAGTACCTATGTTCTCTG TTTTGAATATACTTTAATACCTGAGAGTCTTAAAATTTGTGAACAACGTTTCTATAGTCCTTTATTTTC AAATGCACATTGATCTTCACTTGCTGCATTTTTACTCTTCAACCCTGAAACTATGGTCTACATTAATAT GGATTTTTAAATCACATGTCATTACTTTTGCAACACCATCACCAAAATTTTTTGCTCTTTTACATTTAG GTTCATCTCTGTGGTCTGTGTTGTCCTGACATGTAAAAAGCATATCGTTTATTGAGGTTTTTTTCCCC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_004734.5
Synonyms	CL1; CLICK1; DCAMKL1; DCDC3A; DCLK
Summary	This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. The encoded protein is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis. This gene is up-regulated by brain-derived neurotrophic factor and associated with memory and general cognitive abilities. Multiple transcript variants generated by two alternative promoter usage and alternative splicing have been reported, but the full-length nature and biological validity of some variants have not been defined. These variants encode different isoforms, which are differentially expressed and have different kinase activities.[provided by RefSeq, Sep 2010]
Locus ID	9201
MW	76.2

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