ATM (NM_000051) Human 3' UTR Clone

Specifications

Product Data
Product Name	ATM (NM_000051) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	AT1; ATA; ATC; ATD; ATDC; ATE; TEL1; TELO1
ACCN	NM_000051
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC221017 3’UTR clone of NM_000051 The sequence shown below is from the reference sequence of NM_000051. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CTTTTCCCAGGATGGAAAGCTTGGGTGTGATCTTCAGTATATGAATTACCCTTTCATTCAGCCTTTAGA AATTATATTTTAGCCTTTATTTTTAACCTGCCAACATACTTTAAGTAGGGATTAATATTTAAGTGAACT ATTGTGGGTTTTTTTGAATGTTGGTTTTAATACTTGATTTAATCACCACTCAAAAATGTTTTGATGGTC TTAAGGAACATCTCTGCTTTCACTCTTTAGAAATAATGGTCATTCGGGCTGGGCGCAGCGGCTCACGCC TGTAATCCCAGCACTTTGGGAGGCCGAGGTGAGCGGATCACAAGGTCAGGAGTTCGAGACCAGCCTGGC CAAGAGACCAGCCTGGCCAGTATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCCGAGCATG GTGGCGGGCACCTGTAATCCCAGCTACTCGAGAGGCTGAGGCAGGAGAATCTCTTGAACCTGGGAGGTG AAGGTTGCTGTGGGCCAAAATCATGCCATTGCACTCCAGCCTGGGTGACAAGAGCGAAACTCCATCTCA AAAAAAAAAAAAAAAAAACAGAAACGTATTTGGATTTTTCCTAGTAAGATCACTCAGTGTTACTAAATA ATGAAGTTGTTATGGAGAACAAATTTCAAAGACACAGTTAGTGTAGTTACTATTTTTTTAAGTGTGTAT TAAAACTTCTCATTCTATTCTCTTTATCTTTTAAGCCCTTCTGTACTGTCCATGTATGTTATCTTTCTG TGATAACTTCATAGATTGCCTTCTAGTTCATGAATTCTCTTGTCAGATGTATATAATCTCTTTTACCCT ATCCATTGGGCTTCTTCTTTCAGAAATTGTTTTTCATTTCTAATTATGCATCATTTTTCAGATCTCTGT TTCTTGATGTCATTTTTAATGTTTTTTTAATGTTTTTTATGTCACTAATTATTTTAAATGTCTGTACTT GATAGACACTGTAATAGTTCTATTAAATTTAGTTCCTGCTGTTTATATCTGTTGATTTTTGTATTTGAT AGGCTGTTCATCCAGTTTTGTCTTTTTGAAAAGTGAGTTTATTTTCAGCAAGGCTTTATCTATGGGAAT CTTGAGTGTCTGTTTATGTCATATTCCCAGGGCTGTTGCTGCACACAAGCCCATTCTTATTTTAATTTC TTGGCTTTAGGGTTTCCATACCTGAAGTGTAGCATAAATACTGATAGGAGATTTCCCAGGCCAAGGCAA ACACACTTCCTCCTCATCTCCTTGTGCTAGTGGGCAGAATATTTGATTGATGCCTTTTTCACTGAGAGT ATAAGCTTCCATGTGTCCCACCTTTATGGCAGGGGTGGAAGGAGGTACATTTAATTCCCACTGCCTGCC TTTGGCAAGCCCTGGGTTCTTTGCTCCCCATATAGATGTCTAAGCTAAAAGCCGTGGGTTAATGAGACT GGCAAATTGTTCCAGGACAGCTACAGCATCAGCTCACATATTCACCTCTCTGGTTTTTCATTCCCCTCA TTTTTTTCTGAGACAGAGTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTGGCATGATCTCAGCTCACTG AAACCTCTGCCTCCTGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGT GTGCCAACACGCCCGGCTAATTTTTTGTATTTTTATTAGAGACGGAGTTTCACCGTGTTAGCCAGGATG GTCTCGATCGCTTGACCTCGTGATCCACCCTCCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGC CACCGCGCCCGGCCTCATTCCCCTCATTTTTGACCGTAAGGATTTCCCCTTTCTTGTAAGTTCTGCTAT GTATTTAAAAGAATGTTTTCTACATTTTATCCAGCATTTCTCTGTGTTCTGTTGGAAGGGAAGGGCTTA GGTATCTAGTTTGATACATAGGTAGAAGTGGAACATTTCTCTGTCCCCCAGCTGTCATCATATAAGAT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000051.4
Synonyms	AT1; ATA; ATC; ATD; ATDC; ATE; TEL1; TELO1
Summary	The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. [provided by RefSeq, Aug 2010]
Locus ID	472
MW	76.9

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