TIMP2 (NM_003255) Human 3' UTR Clone

Specifications

Product Data
Product Name	TIMP2 (NM_003255) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CSC-21K; DDC8
ACCN	NM_003255
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC219503 3’UTR clone of NM_003255 The sequence shown below is from the reference sequence of NM_003255. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CAGGAGTTTCTCGACATCGAGGACCCATAAGCAGGCCTCCAACGCCCCTGTGGCCAACTGCAAAAAAAG CCTCCAAGGGTTTCGACTGGTCCAGCTCTGACATCCCTTCCTGGAAACAGCATGAATAAAACACTCATC CCATGGGTCCAAATTAATATGATTCTGCTCCCCCCTTCTCCTTTTAGACATGGTTGTGGGTCTGGAGGG AGACGTGGGTCCAAGGTCCTCATCCCATCCTCCCTCTGCCAGGCACTATGTGTCTGGGGCTTCGATCCT TGGGTGCAGGCAGGGCTGGGACACGCGGCTTCCCTCCCAGTCCCTGCCTTGGCACCGTCACAGATGCCA AGCAGGCAGCACTTAGGGATCTCCCAGCTGGGTTAGGGCAGGGCCTGGAAATGTGCATTTTGCAGAAAC TTTTGAGGGTCGTTGCAAGACTGTGTAGCAGGCCTACCAGGTCCCTTTCATCTTGAGAGGGACATGGCC CTTGTTTTCTGCAGCTTCCACGCCTCTGCACTCCCTGCCCCTGGCAAGTGCTCCCATCGCCCCGGTGCC CACCATGAGCTCCCAGCACCTGACTCCCCCCACATCCAAGGGCAGCCTGGAACCAGTGGCTAGTTCTTG AAGGAGCCCCATCAATCCTATTAATCCTCAGAATTCCAGTGGGAGCCTCCCTCTGAGCCTTGTAGAAAT GGGAGCGAGAAACCCCAGCTGAGCTGCGTTCCAGCCTCAGCTGAGTCTTTTTGGTCTGCACCCACCCCC CCACCCCCCCCCCCCCGCCCACATGCTCCCCAGCTTGCAGGAGGAATCGGTGAGGTCCTGTCCTGAGGC TGCTGTCCGGGGCCGGTGGCTGCCCTCAAGGTCCCTTCCCTAGCTGCTGCGGTTGCCATTGCTTCTTGC CTGTTCTGGCATCAGGCACCTGGATTGAGTTGCACAGCTTTGCTTTATCCGGGCTTGTGTGCAGGGCCC GGCTGGGCTCCCCATCTGCACATCCTGAGGACAGAAAAAGCTGGGTCTTGCTGTGCCCTCCCAGGCTTA GTGTTCCCTCCCTCAAAGACTGACAGCCATCGTTCTGCACGGGGCTTTCTGCATGTGACGCCAGCTAAG CATAGTAAGAAGTCCAGCCTAGGAAGGGAAGGATTTTGGAGGTAGGTGGCTTTGGTGACACACTCACTT CTTTCTCAGCCTCCAGGACACTATGGCCTGTTTTAAGAGACATCTTATTTTTCTAAAGGTGAATTCTCA GATGATAGGTGAACCTGAGTTGCAGATATACCAACTTCTGCTTGTATTTCTTAAATGACAAAGATTACC TAGCTAAGAAACTTCCTAGGGAACTAGGGAACCTATGTGTTCCCTCAGTGTGGTTTCCTGAAGCCAGTG ATATGGGGGTTAGGATAGGAAGAACTTTCTCGGTAATGATAAGGAGAATCTCTTGTTTCCTCCCACCTG TGTTGTAAAGATAAACTGACGATATACAGGCACATTATGTAAACATACACACGCAATGAAACCGAAGCT TGGCGGCCTGGGCGTGGTCTTGCAAAATGCTTCCAAAGCCACCTTAGCCTGTTCTATTCAGCGGCAACC CCAAAGCACCTGTTAAGACTCCTGACCCCCAAGTGGCATGCAGCCCCCATGCCCACCGGGACCTGGTCA GCACAGATCTTGATGACTTCCCTTTCTAGGGCAGACTGGGAGGGTATCCAGGAATCGGCCCCTGCCCCA CGGGCGTTTTCATGCTGTACAGTGACCTAAAGTTGGTAAGATGTCATAATGGACCAGTCCATGTGATTT CAGTATATACAACTCCACCAGACCCCTCCAACCCATATAACACCCCACCCCTGTTCGCTTCCTGTATGG TGATATCATATGTAACATTTACTCCTGTTTCTGCTGATTGTTTTTTTAATGTTTTGGTTTGTTTTTGAC ATCAGCTGTAATCATTCCTGTGCTGTGTTTTTTATTACCCTTGGTAGGTATTAGACTTGCACTTTTTT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_003255.5
Synonyms	CSC-21K; DDC8
Summary	This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq, Jul 2008]
Locus ID	7077
MW	72.8

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