Oligodendrocyte Specific Protein (CLDN11) (NM_005602) Human 3' UTR Clone

Specifications

Product Data
Product Name	Oligodendrocyte Specific Protein (CLDN11) (NM_005602) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	HLD22; OSP; OTM
ACCN	NM_005602
Insert Size	1965 bp
Sequence Data	Insert Sequence (showhide) >SC217095 3’UTR clone of NM_005602 The sequence shown below is from the reference sequence of NM_005602. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CCGACTCATGCGAAGAGTGCCCACGTATAAGAGGGCTGCCCGGCTGCCCACAGAGGTGCTGTAGATGCT GGGCCCAGGGCCCTAGGTTTGCTCGTCACAGTGTGGGGAAGCCCATTCCTCTGCCAGGCTCTAAAGCCA AAGGTCTAGAAAAGCATCCTGTCTGGCATTTTGTAGTCTTAACTTCTCCCCATTTCCCCCATCTTTTGG TTGCCTTAAAAGAAATCTCTAGCTCAGATAATGCCCAGACATTTTTTTCCCTTGGTGTTGCCCCTATTA GCTCTTTTCTTGGGCATTCTTTTGCTGTTTATTAAAAATATATTATATATATTTTGTTTCTTTAAATTT CAAATGTTTTGCAAACATCACTGAGTTAGGTGGGGGTGGGGAAGAGAAATACAAGATACTTTTTTTTTT TTTTTTTTTTTTTTTTTTTTAAATAGGGCCTCACTCTGTTGCTCAGGCTGGAGTGCGGTGGTGTGATCT CGGCTCATGTAGCCTCAACCTCCCCGGCTCAAGTGATCCTCCTGCCTCAGCCTCCCAAGTAGCTGGGAC TACAGGCGTTCACTACTACACCCAGCTAATTTTTAAGTTTTTTATAGAGATGAGGGCTCCCTATGTTGC CCAGGTTGGTCTCGAACTCCTGGACTCAAAGTATCCTCCCGCCTCGGCCTCCCAAAGTGTTGGGATTAT AGGAGTGAGCCACCACACCGGCCAAGATGCTTTTCAAACTGATACAGATGACAATGGGAGCCTCATAAA GATGGCTTTTGTTTCTTCCCTTCAAGGTCATTTACTTGTACGAGACAGAAAAAGATAGCATTGGGGACA TGGGATGGGGGAGGGAGGGCAATAGTGGAACGAACTTTCCATGGGAAACTTTCCCTTTTGTAAGTTGAG GGCCAGGGGTAGGGATATTTTTTAGTTTGTGATTTTACATTTATCTGTACATACTTTTTCAAGATTGAT CATTTTTATAACCATGGTTTTCCTGAAATCCTCAATTCATCAATATGAAGGAAATGAACCACATAGACT TTATGCAATAAATAACAGTGCAAGTGAGTATAACTCTAACTGATGTTCCACAAAACATTTTTGATTTCA GGTTTGTATGATGTAGTTTTTAATCGTACATTTTCATATGCTTCAAACTAACACATTTTTAAAGCTTTC CCCCACTTTTCTCTCTATTTGTATTGTTAGCCATCTTGAAGTGATGTTGTTTAACATAAATTGTACTGT TGAATTTGGCTTTACGGGTGTAAACACTGATGGTATATCAGTATCTGAGACCCCAAACTCTCCAAATAC TGATGGTGCATTTTATTCTTGAAGTGAAATCTGTGCAATAAAATAACAGACTGTCTGCAAAACTGGCCT TCAATCTTCTGTTGTATCCAGAGGTATCATTATTGATTTAAAAAAATCTCATTAATCTCTACTGGTAAT TTATAGGGAATCTGATCAGTGATTCAAGAACAAGTAATTCTGCATTGCCTTGAATAATTAAAAAGTTAT ATTTTATTCACGGTATTGCAGTGGTAATTTGTGGTCATGAAAGCATAACCTCAGTGCTCTCTAGGTTTC TTAAGTGGGGTGACTTTATGGCATCTTTAATCATCGATCAATGGGCAGCAATCAGAAACAAAGTTCTCA GCATTATGCAGTTAATGTCCTTCATCTACTTCTAACACTTAGTAAAGGAATTGATTGGCTAGGTATAAA AAGAGAATTAACGAAACCTATTTTATTGGATCTTTAAGTAATAATATCTAAATACATTTCGTTCAAACA TACATATGTAGCTGTTTGGACATTTTGGACAAAGACACATTGAGTTGATTTTTATTTGTTTTTCTGTTC CAGAAACTTCATCAAGTTACGGGCCTGGTCTAAGAAAACACATTGCAATCTATTTTGGCAGACTTCTTT CAAATAAAATACTAATTTCATTAGCTGATAGTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_005602.6
Synonyms	HLD22; OSP; OTM
Summary	This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a major component of central nervous system (CNS) myelin and plays an important role in regulating proliferation and migration of oligodendrocytes. Mouse studies showed that the gene deficiency results in deafness and loss of the Sertoli cell epithelial phenotype in the testis. This protein is a tight junction protein at the human blood-testis barrier (BTB), and the BTB disruption is related to a dysfunction of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Aug 2010]
Locus ID	5010
MW	75.9

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