TAB2 (NM_015093) Human 3' UTR Clone

Specifications

Product Data
Product Name	TAB2 (NM_015093) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CHTD2; MAP3K7IP2; TAB-2
ACCN	NM_015093
Insert Size	1918 bp
Sequence Data	Insert Sequence (showhide) >SC216991 3’UTR clone of NM_015093 The sequence shown below is from the reference sequence of NM_015093. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GAACAGTGTGAGATGCCAAGGCATTTCTGAGCCAAATGGCCCTGTATCTTCTCTAAAACCACATCTAAA GTTCAAGAAACTAGTCTGTCATCGGGAAAAAGTTTCACTGCTACATAGGATTTTGTCAAATTGAAGGTG TGACAAGATGGTGTTCTGCTAATGTTAAATGTCAGCCCACAGAGCTAATAATACCTCAGTATAATGTCA TGAGCAGTTGAAATTCATCACATGAAAAGTAATCTGCTGAAAGACTTGGTTGCCCACTGCCTAACTGTG TACAGTGTTACCAGTGTCCCATTATGGATAATTCTCAATATGTTAACACCTAGGTGTTCCCAATACCTT TTTCCCCTCATGTCACTACTGAATTTTGACAGGAGGAAGGAATAGAATGATAGCTTGTTTTATTTGTAA AGCTTTCAGTGAAACACTACATACACGAAGAAAAGGAACAAGGTTTAACTATTTAAGAACCATTTGCTG CCGCATAGTGCCATTGGATAGGGAAGAACTTCAGAAATCTGTGGTACTCTTGGCCTTGTCTTTGTCTTC CCTGAACGTGTCTCCACTCTGTGAAGCCAGCATCTAGGGGCTAAAGATGCAAAGGAAAGCAGCATGCAT TGTCTGTACAAATGTGCAGCGAAATACCCCAAAGCTTTTCCTACTGTACAGATCTCTCGAGTCTGCTTT AAGTGATTTCTTTTCTTCTTGATTATTTTCTTATATTTCTATATGTATAGTGTAATAGCCTTTTGTTAA CTAATTTTCTTTTTTCCTTTTAGTAATTAAGCACGATCATGTCCCTTTTTAAGCCTTACCTGAGAGGAA CAATGCCTTAAAATAAAAAAGCATTAATGAGATGAAAGTATGCACAGAATAACTTTCCTCTACTTATTC TGTACTTTGCCCTCATGAGTTCCAATGTTGTGTGAAGACAGGCAGATGCTGCACAGTGAATTGCAGATG ATATTACAGAAGTGATGTCTGTAGGTCACATTAAATACTGACTTGAGCAGTGGGTGACACAACACAGTG TTTGTCTTCCACAGGGAAGCTTAAAACAAAAGATATTTTTAACCCACTGACAGAACAACAAGGTTAAGC TTCATCTGCTTGGTGTCCCACAGAACTTGCACAAGCAGTTGTTATTGGGAAAGTACAGTCTCAAAACCA GCAACAGCAGCAGTACCTACAGCCCTTTTTTTGGAGAGAAGTTTAAATGCTTTACTGTTGGGGCAGTCC ATTTCTAATCCTGACTTGGTGACAGTATCATGTGTATTTATAAAACAAGGCTAGCCATATTTAGGACAA CTGAAGAAAAGCTGGAAAAAAAAACAAGCAAACTTGAACACTGAAGCAACCTCAAGCATCTCTTTATTT TGATGATATATTTTTGTAAGGAAAATATTCAGATGATCAGGAATGTATATAACTGAAATCAAGAAAAAG AACAGTATGCATTTAAAAAGACAGAATTATGAAATTATATGAGTGCTTAGAATGGGGCTAAGGGAAGTG CTGAAATAGAGCAAAGGATGGAAGATAATATAGACTACCACCCACTGTAAATGTTTGCAAGTGGCTGTG TTTTAAATGGGATTATTACAGTTGATCTCTATGAATGTCAGAGCCCTAACTTTCAGGCTTTGCATTTTG TATATGGGAAGAAATATGACAATCCTAGGTAATTAAACCATAGACCCAAAGCCCTTACGTTTGATGCAA TTTATTTTTAAAATAGGCCTTGTTTTTCAGCTTCATCTGCAGTTCTATGTGAAGATTGATAAATCAGTT TTTACTTGTTTTATTAATAAAACGTAATTTGGATATCTTGAGTTGATGGTTTTGTGATTTAGCTGGGTA AACTATCTTTGTAACAGATAAGTTATTTATAAAAATTAAAAAACTTATATTCTAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_015093.6
Synonyms	CHTD2; MAP3K7IP2; TAB-2
Summary	The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, and it thus serves as an adaptor that links MAP3K7 and TRAF6. This protein, along with TAB1 and MAP3K7, also participates in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappaB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. Studies of the related mouse protein indicate that it functions to protect against liver damage caused by chemical stressors. Mutations in this gene cause congenital heart defects, multiple types, 2 (CHTD2). Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Locus ID	23118
MW	74

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