LAT2 (SLC7A8) (NM_012244) Human 3' UTR Clone

Specifications

Product Data
Product Name	LAT2 (SLC7A8) (NM_012244) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	LAT2; LPI-PC1
ACCN	NM_012244
Insert Size	1912 bp
Sequence Data	Insert Sequence (showhide) >SC216953 3’UTR clone of NM_012244 The sequence shown below is from the reference sequence of NM_012244. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AAGGACGTGGCGGGGCAGCCCCAGCCCTGAGGACCACCATTCCCTGGCTACTCTCTCCTTCCTCCCCCT TTTATCCTACCTCCCTGCCTTGGTCCTGCCAACACATGCGAGTACACACACACCCCTCTCTCTGCTTTT GTCAGGCAGTGGTAGGACTTTGGTGTGGGTGGTGAGAAATTGTAAACAAAAACTGACATTCATACCCAA AGAACCAGCCTCTCACCCCAGGGTCCATGTCCCAGGCCCCACTCCAGTGCTGCCCACACTCCCAGCTGC TGGAGGAGAGGGGAGATGCCAAGGTGCCCTGCAGGACCTCCCTCCGGGCCACACCCTCAGCTGCCTCTT CAGGAACCGGAGCTCATTACTGCCTTCCCTCCCAGGGAGGCCCCTTCAGAGAGGAGAGGCCACAGGAGC TGCATTGTGGGGGGACAGGCTCAAGCAATTCTGTCCCCATCAAGGGGTCAGCTGGAGAGACCCAAGACC CTATCTGTTCACCAGGGACCCAAAATCCAAGGGGATGCTTCCCTCTGCCCTCTTTCCTGCCCCTCCCCA TCATACCTGCACCCACCCCAGCCAGGGCTCCCTGTCCAGAATTCGGTTCTCCTCAGGACGCCAACTCCC AGAGCTAAGGACCAAGGAGAAGAACAGCCTCTCCACCCCCAAGCCAGGCGGTTGAGGAACATATTGAGA AAGGTTCAGATTGCAGAAACCCAGCCCTGCCCCTGCCTCCTGCATCCAGCCCCCAACATGGTGCCAAAG CTTCCAGAAGCCAAAAAGCTTCTGATTTTTAAGGTAGTGGGCATCTCTCTCCTAATGACGAAGCTGCTC AGCAACTCCACCTGCCCGCCGCAGGAAGGAGCAGTCCCCTGCTATCCCTGCAGCCACTCCCAGCACACC CGCACACAGCCAGCACCACCGCCCCCACCGTGCACTTCTCCTCTCTGGGCCTTGGCTTGGGACCAGGTA CGAAGGATCCCCAAGCCCTTCAGGCCTGAGATCAGAGCCAGATCAGCCTTAAGTCACCTCCCATCCAAG AACTTGGCCTAAAAATACTCCCCTATTTCTAACCCTCAGGACGGATCTGATATTAAATGCCTTCCCTGG GAGGAAGGGTGCTTTCCCCCTCCCTAGAGGTGCCCATTCCATACCCTGGGAGACTGAGGAGAGCATTGG CTGAAGCCCAGTTCCTTTCCCATCCATCCCCAACTCCAATAATCCCCCACTCCTCGCAGGTCTCAGTGT CATGCTGTCTTGGGGCAGGGTGAAAGGGTAGTGGCAGCAGGGCGCCCACTCTGGAGATCCTCAAAAAAG GCCCTCCTCTGTGGCTGGCAGCCTCTGACCTTTCCCTGGGCTTCAAAGGAAGGCTATGGAGTTTGCTGT GGGCCCTGCAACCTTCCCAGCCACTCCTGCTGCACTAAGGACTTAGGATCCTTTTATCACAAATCGGGA TTCTCTCCCCCACCCCGAATTCTGTCTGCTTAAACTGGAATACACAGGAGCCCTTCCTGGCCTGGATGG TGTCTCCCAGCTTCCCCGCCCAGCTTGCCCACCCCATAGTTGGTGAGATGCCAAGTTTGGTCTGAGTTG TGACCCCTTCAGAGTAGATGCCCGGCAGGCTGGGGTTGGCCCCTGGAGGGTCAGGGGACCATCTTCTTA TTCCCTCTTTTCTCATTCCTCCAACTTCCTCCCCTCCTTCAATTATTTTTTTGTAAAGTTGATGCCTTA CTTTTTGGATAAATATTTTTGAAGCTGGTATTTCTATTTCTTTTGGATTTTTTTTAATGTAAGGTTGTT TTGGGGGATGGAGTTAGAACCTTAATGATAATTTCTTTCGTTTGGTGTAGGTTTTAGAGATTTGTTTTG TGGAGAGGTTTTTTTCTTTTGATGTAATAAAATTTAAAATGGAAATGAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_012244.4
Synonyms	LAT2; LPI-PC1
Summary	Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Plays an essential role in the reabsorption of neutral amino acids from the epithelial cells to the bloodstream in the kidney.[UniProtKB/Swiss-Prot Function]
Locus ID	23428
MW	70.5

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