KDELR2 (NM_001100603) Human 3' UTR Clone

Specifications

Product Data
Product Name	KDELR2 (NM_001100603) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ELP-1; ELP1; ERD2.2; OI21
ACCN	NM_001100603
Insert Size	1907 bp
Sequence Data	Insert Sequence (showhide) >SC216938 3’UTR clone of NM_001100603 The sequence shown below is from the reference sequence of NM_001100603. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GAGGAAAAGAGCCAGAAGGTTTCTGTTTAATGCATCTTGCCTTATCTTTTTTTATTACTGTGTACAAAG ATTTTTTTACACAAAGAAACTTAATGCTGTATTAATAAATTCAGTGTGTAGCTTCAATTGGGATAGTTC CAAAAGTGAAGATTTTGTGAGGAATAAGTGCAAATTTTTTTTTTATTTTAAAAAATTCTTTGAAACTCT TAAGTCTTTGTGTCTGCAATGAAATTGTACTCCTTGACAGTTGATAGATTATATATTCTTCCATCCCTC AAACTTGCATTCCACTATATTTATTTTTTGGCAAAAGATGAGCTGTATTTGTTTGAAATCTGAGACACT ATGTTCAATTGGATGTATCTGTTCAAATTTATTCCCACGTGACGTGGAAGTCCTTCGTTGGATGTCACA ACACTACATTTAAGGTTGGTAAGGATGACTTGGAGGTCCATGGTTTTCATTACCAACATTTTAAGATTC TGAATGTCGATGGAGTCTCACTGAAGAGTCACCAAAGGTGCCTGCCCTCCTCCCCTGCTGGGAAGTGTC AGTTGGAGACTGTCCCAAGGGTGCTGAAGAATCCAGTGGCAGGGGTTCTGGCTGCTTTCCATCTGAGTG TGGGATGGGAGGGGTGTTCATGATCATTTGGATATAGCAATCTACTCTGAGAAATGGAACACAAGGAGT TACCTATCACTTTCACTTATAATTCCAAAAGATGACTACAACCATGTCCATGCTCAGATTCAAACAGTT TTCCATATCACTTTTGGGTGGTAAGATGATTTAATTACAGTTTTTTTTTTAATTGGCAGCACCACTAAC CATTCCTTACATTCTTTTTTGTATGTGTGGTTTTCTTTTTATTTAACCCGCAGCCGACATCGTAGTTTC TTGTTTTGTTTTGTTTTACAGAGCTGTTGCATGACTTATGTTACCATCCTAAAAAACACTATATTAAAC ATGGAATAAATTGTCTTTTTATGAATTAGGCTTTTTGAACATCCTGTGTTGGGATTTTTTTGTTTTTCA ATTGGCAACAAAAGCTCTGTAGGGCTGCAGACATTTAAAGTTCACATAATCATCTGTAAGACATTATGT ATTTTGTGGAAATACTAGAATTTTTTTCCTGATTTTGCCATTATATGGATTTGCTATTTTTTGATTAAT GCAAAAGTATATGACTTTGTTTTTTATGTGATACACCATAAATATTAAAGTGTTGAATACTAACAGTGC TGACTACAAGAAGGATGTAGTATTTTGGCTTTCTGCATTACAACGTCTTCTGGAGGAAGGGAGCAGGAT GGGTTTCATTTGTATCTAGTGTGTGTCTTAACATCTTTCTAAATCGGCAGTGTAACTGCATAGTTTAAC TTCCTGTCTGTCTCCCTCATTTTACTCTTCCCTCCTTGTCTTATGTTTTGGCTTTTGTGTATCAGAGCA TCTTTCTTTGCAGCATCCTAGTCTTGCTTCAGTTTCTGTGGTCTCTTTTCATCCTGCTTGAAGATTCGG AGTGTGGAAGGAGGCTAGGAAGTCTGGTGCAGTAGGTGAGCAGACCTCTTGCTGCCCAGCCCAGGGTGG GTGGGGCGCACACCTGTCTTTGTGCATGCAAATCTGATACACCTGGCGCATCCTCTGGAGAGCACAACG CATGGAAAGGTCTGGAAGCTCTGTGTAGCCATTCCTTCTGCAGTCATCCTACCCAAGTAAAAGTAACCT TGGCTATGTTACCACCGTTTTGGTCACCCAGGAGGACATCTTAGCAAGGGTGCCTGCGAGGGAGTGTGG GACTGGGCCTCATCCTCGCCGGCGTTGGAAACCAAGGCCTTGTATGCCACGCCTTATGAAGCACTGTTT CACAGTTACTTTCACTTCCCGAATAAAGGTTACCAGGTAATTAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001100603.2
Synonyms	ELP-1; ELP1; ERD2.2; OI21
Summary	Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. KDELR2 was the second member of the family to be identified, and it encodes a protein which is 83% identical to the KDELR1 gene product. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Locus ID	11014
MW	73.6

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