Myosin light chain kinase (MYLK) (NM_053032) Human 3' UTR Clone

Specifications

Product Data
Product Name	Myosin light chain kinase (MYLK) (NM_053032) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	AAT7; KRP; MLCK; MLCK1; MLCK108; MLCK210; MMIHS; MMIHS1; MSTP083; MYLK1; smMLCK
ACCN	NM_053032
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC216632 3’UTR clone of NM_053032 The sequence shown below is from the reference sequence of NM_053032. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GAAGGGGAAGGGGAAGAGGAAGAAGAGTGAAACAAAGCCAGAGAAAAGCAGTTTCTAAGTCATATTAAA AGGACTATTTCTCTAAAACTCAAAAAAAAAAAAAAAACTCAAGATAGTAAAAGCACCTAGTGTGATAGA TTATCGGTTAGGTCATTTGTGGGTTGATTCTTCAGAAACAGCAGTTGATACCTAGCAGCGTTATTGATG GGCATTAATCTATGTTAGTTGGCACCTTAAGATACTAGTGCAGCTAGATTTCATTTAGGGAAATCACCA GTAACTTGACTGACCAATTGATTTTAGAGAGAAAGTAACCAAACCAAATATTTATCTGGGCAAAGTCAT AAATTCTCCACTTGAATGCGCTCATGAAAAATAAGGCCAAAACAAGAGTTCTGGGCCACAGCTCAGCCC AGAGGGTTCCTGGGGATGGGAGGCCTCTCTCTCCCCACCCCCTGACTCTAGAGAACTGGGTTTTCTCCC AGTACTCCAGCAATTCATTTCTGAAAGCAGTTGAGCCACTTTATTCCAAAGTACACTGCAGATGTTCAA ACTCTCCATTTCTCTTTCCCCTTCCACCTGCCAGTTTTGCTGACTCTCAACTTGTCATGAGTGTAAGCA TTAAGGACATTATGCTTCTTCGATTCTGAAGACAGGTCCCTGCTCATGGATGACTCTGGCTTCCTTAGG AAAATATTTTTCTTCCAAAATCAGTAGGAAATCTAAACTTATCCCCTCTTTGCAGATGTCTAGCAGCTT CAGACATTTGGTTAAGAACCCATGGGAAAAAAAAAATCCTTGCTAATGTGGTTTCCTTTGTAAACCAGG ATTCTTATTTGTGCTGTTATAGAATATCAGCTCTGAACGTGTGGTAAAGATTTTTGTGTTTGAATATAG GAGAAATCAGTTTGCTGAAAAGTTAGTCTTAATTATCTATTGGCCACGATGAAACAGATTTCAACTGAT AAAGAGCTGGAGAACTCCATGTACTTTGGAATCTCCTCCAAGATAGCCAGAGTTTAATACATCTTCATT CTCAACACTCTCCAAAGAACTTGACCTACCTTATGGGTTCCATATTTTTCTTCTTAAATGTGCATCAAT CATGCCTTGCCCCCAACCTTTAAATATATTCTTAGACCTGGTAAATGCACTCAGACTTGCGTCTTTAGG AATTTTTAACTTTCTTTCACTACATTGGCACTTAAATTTTTTCTTTATAAAGCTTTTTGAAGGTCATAA ACAAAGACCATAATTGATGATAGACCTAATACATTTCCTCTGTGTGTGTGTGTAACATTCCAAATACTT TTTTTTTCTTTTCCACTGTTTGTAAGGTGCAACAATTTAATATTTTTAAGGGACTTTTTAAGAGTTCCT TAAGAACCAATTTAAAATTACTTCAGTGCAATCCTACACAGTATCAACATTAGAATTTTGATATTAGTC TTATGTTATCTTCCATTCTATTTTTATCTGCTTTTTGCTGCTAGTTTCAAACTGCCAGTATTTTTCCTT TTGCTTTTAAAATAGTTACAATATTTTTCATGATAGCCACAGTATTGCCACAGTTTATTATAATAAAGG GTTTTTATTTGATTTAGCGCATTCAAAGCTTTTTTCTATCACTTTTGTGTTCAGAATATAACCTTTGTG TGCGTGTATGTTGTGTGTGTGCATGTGTGGCGTATATGTGTGTTACAGGTTAATGCCTTCTTGGAATTG TGTTAATGTTCTCTTGGTTTATTATGCCATCAGAATGGTAAATGAGAACACTACAACTGTAGTCAGCTC ACAATTTTTAAATAAAGGATACCACAGTGCATGCTGTTTGTTCAATCTTTGCAGACTTCTCTTTCTTTC CATGCTACCAGTTGTAAAGGACACAGCTATATCCTGGAAATGAAAAACAAACACTGTGGTGCCTAGATG TGAAGAACTGGCTTATGTGGTTGTGTTTTGCTATGGAACAGAATGATTTAGGAAGTTCTTGTTTATAT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_053032.4
Synonyms	AAT7; KRP; MLCK; MLCK1; MLCK108; MLCK210; MMIHS; MMIHS1; MSTP083; MYLK1; smMLCK
Summary	This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts. [provided by RefSeq, Jul 2008]
Locus ID	4638
MW	77.2

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