PRPH2 (NM_000322) Human 3' UTR Clone

Specifications

Product Data
Product Name	PRPH2 (NM_000322) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	AOFMD; AVMD; CACD2; DS; MDBS1; PRPH; rd2; RDS; RP7; TSPAN22
ACCN	NM_000322
Insert Size	1727 bp
Sequence Data	Insert Sequence (showhide) >SC216080 3’UTR clone of NM_000322 The sequence shown below is from the reference sequence of NM_000322. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GACGCAGGCCAGGCCCCAGAGGCTGGCTGAGGGCCCTGGGGCCCCTCCCCTCCCGAACACTGAGAAATA GTGCACTCCAAGAAACGTGGATCTCCCCCTCATCCAACTCCGAAAGTCTGAATCTCCCAAGGAGGGCAC CATCTTACAGAGACTCTCCCTGACGGTGGAATTTAAGTTTAGGGTCCCTAAAAGCATTTGACACACAGT TGTTGAATGACTGACCCAAAATGTGAATGAAGCTAATGTGAATGTGAGTGAAGCTCCCTTCAGGCCCGC TGCCCTAGGATATGCCCTCCTGGTGACTCGGGGGCTGTCTCAGACGACTAGCCCAGGACCCATCTTTCT CACACGGATTTAGTCCCACCCTATGGCCACTGGCCGTATCTGAGGGCTGCTCCCCTTTTAGAATTTACC TCTTATGAGCTCCATGTTGCTTCACTCTATCCAAAGTGTCACTTGGTGCATAAGCACAGAAATCTGAAA AATGGCCATGTTGTCTTTTTTTTTTTTTTTTAATGCCAAGATTGACAGGTTGGCCGTTTGCTTAATGCC AGAAGTTGGGGGAAAGTTACGCTTTTCTAAGAATAATGGACTCTTAAGGCATTGAGGGCTCTAAACAGG ATTCTTTAATCATGGAGCAAGAGAATTTCAAGGCAGGGGATTTTATCCCCCACCAAAAACACAGTGAAA GGCCTGCTTTTGTGTCCCATTCACATGCCCTCGGTCACTGAGTCTGGAGTGAACCACGGGTTGAGGAAG TCAGGCTGTTGGCGTGTCCCAGCACCACACCACCCCTAAAGTGCCAGGTGATCTCCTGTGGCTCATCGG TGGAAGCAGTGGGGTAGGCTGCTGCCCTGCTGTGGAAGAGGAGCAACAATCAGACATGAGTCCACCCTT TGGAGACCAGGCCTCAGCTCTTGGTGGGCCCAGGGACACCCACACAGGTGGCCATCACAGCCCCATGGA CAACACTAATTGTCCACAGCAAAGGGCAAGGAATCCTCTGGGAGCTTCTTCCGTTTCTTCCCCCCAGAT ACCCATCTTGAAAAACACTATTTCTGGAATGCTTCTGCATCAAAGGAGATTCTTTGAGATAGCCCATCT TCCTGAGCTAGCAAATACAGGAGTTTTCACTTTCTTTAGGAAAGAGAAGCTTTCAGGGGAAGGAGAGAA TGATTTTGCTGACTTCCCAAGCCCTGGTGACCAGACCAAGGCAGGGCCCAGCATAATTCCTCCAGTTGG ATGAACATTCAAGAGAGCTCGTTCCTACCTGGCTGGAGACCGAGGCCAGAAGGCAAAAACCAGAAAGGG AACAGTCCATAACTTACCTCTGCTTCTGACCGATGGTGTTTGGGAATAGGTTACTTTGGACTGAGTTTG GGTTCTCTGCTGTCCTAAGAACTTCAGTGTAGAGAAAATAAGACTTCTGGTGCTGCTGGGGTATGTTCT GGGCTTAATTCCCCCAAGCAGAAGACCAGATCCAAGATGTTTGGACACCCTGTCAGACGTTGGTCCCAA GTTTAATTAGATTTCTGAATCTCGTTGAGGCCAAGGAATGATCCATACTGAAAAAATGCTGAGCCAGCC ATCTTTGGCAAAGGTCCCTGAGCTCTTGCTATCTCTCAAGAGTGCTGAGAACCACGGTGAAAGTGCTGC TCTAGGCCCACAAGTGTAACTATGCTGTTAACAGCTGTCAATAGATAATTAAAATTCATACTGTATGAA AA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000322.5
Synonyms	AOFMD; AVMD; CACD2; DS; MDBS1; PRPH; rd2; RDS; RP7; TSPAN22
Summary	The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein found in the outer segment of both rod and cone photoreceptor cells. It may function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. This protein is essential for disk morphogenesis. Defects in this gene are associated with both central and peripheral retinal degenerations. Some of the various phenotypically different disorders are autosomal dominant retinitis pigmentosa, progressive macular degeneration, macular dystrophy and retinitis pigmentosa digenic. [provided by RefSeq, Jul 2008]
Locus ID	5961
MW	64.7

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