PICALM (NM_007166) Human 3' UTR Clone

Specifications

Product Data
Product Name	PICALM (NM_007166) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CALM; CLTH; LAP
ACCN	NM_007166
Insert Size	1901 bp
Sequence Data	Insert Sequence (showhide) >SC215630 3’UTR clone of NM_007166 The sequence shown below is from the reference sequence of NM_007166. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GTATCAGGAGCACAGATACAGTTTATGTAACTTGATGGAAGAAAATGGAATTACTCCAAAAAGACAAGT GCTCAAGCAGCAAAATCCTTACTTCCAGCAAAATCCAAACTGCTGTCTCTTAAATCTCTTAAACTCTCT TCTTCCATTAGAATGCTACAAGTAACTCAGTGAAGGCCCATGAAGGAAATTGGGACTAGTTTATAGGAG AACGTATCAATACAGTTTATAAAGCCAAGAATTGCTATGATTTAAGACTAAGATCTGTCTTTTTGGTGA CTAACCCTTCAATTCTTTCAACTCCTGTTAATACCCATAATCAGTAACCTATCAAGAAAAGCCCTTATT TGGAAAGTGTGAAATTTGTATTTGGAAAAGCTGCCTGGAGAGAAGAACTGTGTCCTTTACTGTATTTCA ACAGGACTCTTTTGGGGGATCAAAATTAAAATTCCTAATTATGCATTATCTTTCTTTTCTCCAGTCCTC ACAAATACAGAAACAATAACTGAAATTAACTTTTCTTTTTTTAAAAAAAATTATATTCAGTTTGCAGTA GACATTCCTTAAGTATTTGTATTTATTTATGATTATCAATTTTACATAACATTAATATTGTATCAGACC TCCTTATGAAAATGAGTATGGATGTGCACAGTATGTTTGATTTTTATCCACAAGAATGAATCTGATTCA GAATGCTTTTCTCAGCTGACATACAGAGCACTAAATATTTTAAGGCAAGTCCATAGGTCTGAATCTCTT AAGAATTCTCGGCCTCTGTGGGATTTAGGGAAGCATTATAAATGCATTAATCCTTATAGTCAATTCTGT GCCTAGGATTTTGCCAGGGAACAGTTCACTGACTAGGAAAAGCACTACATTTTAAATTCAGCATTAGTG CATTGGGAAGGATCTTTACTGCTTTGTGCTTGGCATGTCATTATTTTCCATTTGACATTAGGGCCTTTC CAAAATGAATGTGAGGAATTGCTTTCACTTCAAGACTTTCCTTCTTTTCACTAAAACTCTAGAAGGTGT TACAAGGGGGAGGGAAGGGGGGCAAAGTCCTTGAACATTTTCTTTGGCTCGTGCCATGTTATGATCATA TACCTTTTAAATAAGGGGAAATAGTATCTTTAAAGTTAATGTCTAGCCAAGAGTTTAGTAAACGAAGAA TTAAACTGCACTGTTGATCGGTGCTTTGTGTAAATACATCTTTAACATTTGGGTGGAGAGGGGCCTTAA GAAGGACAGTTCATTGTAGGAAAGCAATTCTGTACATGAGTTTAAGCATTCTTGTTGCATTGTCTCTGC AGATTCTATTTTTGTTTACAATATTAAAATGTATGTTAGCAAAATGGGTGGATTTTCAAATAAAATGCA GCTTCCACAAAAGTTTTGTTATGGTATTCTGGTCTGAGATGCATTTTCATTTTTCCTTTCTCTTTTTAT TATCAATATTGTCATTTTTCCCTAATAAAATATACCCAGGTGATTATATTTGTTGATCTAATAACATGG AAGGTTTGTTTTATATGAATTTTCAAAAAGATGTCTCTTTACACTTTTTGTTACCTTGTAGACTCTTAT TGATAAATGCAACTACTTATTAAAATTGTTCACTTTTTGTCTTTTGATCAGATGCCTTTAGTCAGGTAA GTTTAAGGGAAAATACGCAGTTTAATGTTTTGGTACATATAATTATGTCTGCCAAAGAAACCTTTGATT GTATCATATTGCCTATTTAGTAGTGCATAGGGTTCAGAGTACATGATAAAGGATCAAAAGCTTTGCATT GATAAGTGTCTCATAATATTTGCTGTGATTGGAGAAAAAATGTAGTCGTAGCCAATAAATTTTATCAGC TTTTAAGTTTCAGTATTATTAAACCATTTTCATATAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_007166.4
Synonyms	CALM; CLTH; LAP
Summary	This gene encodes a clathrin assembly protein, which recruits clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. The protein may be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. The protein is involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. A chromosomal translocation t(10;11)(p13;q14) leading to the fusion of this gene and the MLLT10 gene is found in acute lymphoblastic leukemia, acute myeloid leukemia and malignant lymphomas. The polymorphisms of this gene are associated with the risk of Alzheimer disease. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
Locus ID	8301
MW	73.9

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