LOX 1 (OLR1) (NM_002543) Human 3' UTR Clone

Specifications

Product Data
Product Name	LOX 1 (OLR1) (NM_002543) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CLEC8A; LOX1; LOXIN; SCARE1; SLOX1
ACCN	NM_002543
Insert Size	1609 bp
Sequence Data	Insert Sequence (showhide) >SC215522 3’UTR clone of NM_002543 The sequence shown below is from the reference sequence of NM_002543. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CAGAAGAAGGCAAACCTAAGAGCACAGTGAATTTGAAGGCTCTGGAAGAAAAGAAAAAAGTCTTTGAGT TTTATTCTGGAATTTAAGCTATTCTTTGTCACTTGGGTGCCAAACATGAGAGCCCAGAAAACTGTCATT TAGCTGGCTGCAGAACTCCTTTGCAGAAACTGGGGTTCCAGGAGCCTGGCACCTTTATGTCAACATTTT TGATTCTAGCTACCTGTATTATTTCACCTAGCTTGTCCCAAGCTTCCCTGCCAGCCTGAAGTCCATTTT CCCCTTTTTATTTTAAAATTTGACTCCTCTTCAAGCTTGAAAACCCTCTGAACTCAGTCTTCTTTACCT CATTATCACCTTCCCCTCACACTCCTAAAATTGCATGAAAGACAGAACATGGAGAACTTGCTCAAGTGC AGGCAGAGAGCAAAAAGGGGAAATATGTCTGGGAAAAAGTGCACGTGAAGAAACAAAGAAGGACAGAGG CCATTCCGAAATCAAGAAACTCATGTTCTTAACTTTAAAAAAGGTATCAATCCTTGGTTTTTAAACTGT GGTCCATCTCCAGACTCTACCACTTACGGACAGACAGACAGACAGACACACACACACACACACACACAC ATTTTGGGACAAGTGGGGAGCCCAAGAAAGTAATTAGTAAGTGAGTGGTCTTTTCTGTAAGCTAATCCA CAACCTGTTACCACTTCCTGAATCAGTTATTATTTCTTCATTTTTTTTTCTACCAGAGGACAGATTAAT AGATTTAACCCTTCACAACAGTTCTTGTTAGAATCATGGGATGTGTGGCCCAGAGGTAAGAATAGAATT TCTTTCCCTAAAGAACATACCTTTTGTAGATGAACTCTTCTCAACTCTGTTTTGCTATGCTATAATTCC GAAACATACAAGACAAAAAAAATGAAGACACTCAATCTAGAACAAACTAAGCCAGGTATGCAAATATCG CTGAATAGAAACAGATGGAATTAGAAATATATCTTCTATTTTTAGGCTTCTATTTCCTTTCCACCCACT CTTCACAGGCTATTCTACTTTAAAGGAAGCCTTTTTATTTTGCTGCACACAATCTAGCAGGAATCTTTT TTTTTTTTTAAGAGCTGTGTCATCCTTATGTAGGCAAGAGATGTTTGCTTTTGTTAAAAGCTTTATTGA GATATAATTAACATAAAATAAACTGAACATATTTAAAGTGTACTATTTGATAAGTTTTCACACCTTGTG GAGAACATGCATACTACAATTAAGAGAGTGAACATATCCATCATCCCTCAAAGTGTCACAATGCTCCTC CTGATGACTCCTCCCCAGAAAACCACCAATCGGCTTTCATTTTGCATTTTGTAGTTTTATGTGAATGGA ATCATATAGTATGTCTTTTTTTTTTGTCTGGCTTCTTTCACTTTGCATAATTATTTTGAGATTCATATG TCTCCATCTTGATGCTCGTATGAATTCATTCTTTTAAATGTTGAATATTCCCTTGTATGGATATACCAC AATTCATTTACCCATTTACTTGTTGATGACATTTGGGTTGTTTTAGTTTTGGGATATTACAAATAAAGC TGCTGTGAACATTTGTGTACAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_002543.4
Synonyms	CLEC8A; LOX1; LOXIN; SCARE1; SLOX1
Summary	This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]
Locus ID	4973
MW	63.2

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