GLUD1 (NM_005271) Human 3' UTR Clone

Specifications

Product Data
Product Name	GLUD1 (NM_005271) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	GDH; GDH1; GLUD
ACCN	NM_005271
Insert Size	1579 bp
Sequence Data	Insert Sequence (showhide) >SC215287 3’UTR clone of NM_005271 The sequence shown below is from the reference sequence of NM_005271. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TACAATGAAGCTGGTGTGACCTTCACATAGATGGATCATGGCTGACTTCCTCACTATCCTCTTCACATG TAACTTCTGCAGACCTATCACAAGTTTACATGTAACCACAGAAATCCCTTTCTCTCCTGACTCATTAAT AATGGATACCATTCTCAACAAGTCAATCCAAGTCAGCCCGTTAAGGAGAAAGAAATTAAGGTTAGCGGA TCATGTACAAGCTGAGTGTGAAAGTAGAAATCACCTACACCAGAGAGCCATTTTGGTATTTTGCCTTTA AATAAAAAGCCTCCTTTATCTGGCTGTGCAGCCTTGCTCTGTGGCTTTTCCCAACACAATCAGTGCTAG TGCTGGGGAGGAACAGTCAAGAGCAGTCAGTTGCTTGCTTATTTTTTCTGGATGAGTCTGGGACACACT GTAACTTTAACACATTTAAGAAGTAGGTGTGTGGCCTTTTCAGAAGGTGGCATGGTCCTCAAGTGAGTT CTTAGTATTTTATATCAGCAAAATAATTCAATTTTGCAGGTTGCAAACAAATATAAAACCTGTTTCTGT TTATGAATATTATTCTTTTAGAATAGAATAAGTACATGCTGCTGTAATAAAATTGCCTTTAATCACTTA ACAAGCCTAACCTTGACTCAAACAGTGAATGCCTATAGAAATAATAAATGAAAAAAACTAGTATTTTTA TATCATAAAACAATGTCATTTATAGCTTATCATTCATGTATTGTCCAGCAGACATTAAAAGCCCTGTGG ATAATTAAGTTATCTTCATACCTGCAAAATGGTGGAGGCTATTTTCATTAAAACTGTCAGAATTTGCTT ACTATAATTATGATACAGTCCAAAGAATGCAGTCACTTTTTATCATGTTAACTAATTGTTCTCTTTTGA AGATCTATGGTTGACTAATTAAACAATAATTCAAGTAGAGTGTCCCAGAAAAAAACCACTTGGGCTCCC TGTTTGGAGTCTGGCTGGCTCTGAGCATTGCCAATGGCCCCTACTCACCTGACTTTGTATCCTCTCCTT TTAGAGGCTTTGCATTCTGCACCCAGCTTCACTAACAGTGGGCTGAAAACATCCTTGGGTTGAGTGTTT CATTTGGGAGTTATTTGGCCAGGGCCTTTTGAACAGTAGTGTCCCCATGAAGTGCTAGATAATATATGT GTAAGAGTCAGCTTTTTTTTTTTTTTTAACTCTAACACCCTTCAGAAATTTCTAACTACTTTGTAACTG CATGGCTTAACCTGGTGATAAAAGCAGTTATTAAAAGTCTACGTTTTCCAAAACTTACGTTTCTTTTCT GTGTTTTTACATGTGGTAGTTTCTCTTTTCATAAGTTATAATACTGCAATTGGATTTCTGAAATGTTTA TAGCGACCACCTGTATAACATTTCCTTCCACTTTATTGTGAGCTGCCCAGATTTTATTCTTGAATTGTT TTTTTTTTTTTTGTTCGGTGCTTTACACGTTCAGAGAAACTTCCCGAGTAACGAACTATAGAAATGATC CCTGAAAGCATAGTCTTTATTCTCGAATTATTTTGTATTTTATTAAATAATATGAACAGCT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_005271.5
Synonyms	GDH; GDH1; GLUD
Summary	This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X. [provided by RefSeq, Jan 2016]
Locus ID	2746
MW	60.3

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