IL21 Receptor (IL21R) (NM_181079) Human 3' UTR Clone

Specifications

Product Data
Product Name	IL21 Receptor (IL21R) (NM_181079) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CD360; IMD56; NILR
ACCN	NM_181079
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC215001 3’UTR clone of NM_181079 The sequence shown below is from the reference sequence of NM_181079. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CTTTCGAGCCCTGGACCCCAGGCCAGCTAATGAGGCTGACTGGATGTCCAGAGCTGGCCAGGCCACTGG GCCCTGAGCCAGAGACAAGGTCACCTGGGCTGTGATGTGAAGACACCTGCAGCCTTTGGTCTCCTGGAT GGGCCTTTGAGCCTGATGTTTACAGTGTCTGTGTGTGTGTGTGCATATGTGTGTGTGTGCATATGCATG TGTGTGTGTGTGTGTGTCTTAGGTGCGCAGTGGCATGTCCACGTGTGTGTGTGATTGCACGTGCCTGTG GGCCTGGGATAATGCCCATGGTACTCCATGCATTCACCTGCCCTGTGCATGTCTGGACTCACGGAGCTC ACCCATGTGCACAAGTGTGCACAGTAAACGTGTTTGTGGTCAACAGATGACAACAGCCGTCCTCCCTCC TAGGGTCTTGTGTTGCAAGTTGGTCCACAGCATCTCCGGGGCTTTGTGGGATCAGGGCATTGCCTGTGA CTGAGGCGGAGCCCAGCCCTCCAGCGTCTGCCTCCAGGAGCTGCAAGAAGTCCATATTGTTCCTTATCA CCTGCCAACAGGAAGCGAAAGGGGATGGAGTGAGCCCATGGTGACCTCGGGAATGGCAATTTTTTGGGC GGCCCCTGGACGAAGGTCTGAATCCCGACTCTGATACCTTCTGGCTGTGCTACCTGAGCCAAGTCGCCT CCCCTCTCTGGGCTAGAGTTTCCTTATCCAGACAGTGGGGAAGGCATGACACACCTGGGGGAAATTGGC GATGTCACCCGTGTACGGTACGCAGCCCAGAGCAGACCCTCAATAAACGTCAGCTTCCTTCCTTCTGCG GCCAGAGCCGAGGCGGGCGGGGGTGAGAACATCAATCGTCAGCGACAGCCTGGGCACCCGCGGGGCCGT CCCGCCTGCAGAGGGCCACTCGGGGGGGTTTCCAGGCTTAAAATCAGTCCGTTTCGTCTCTTGGAAACA GCTCCCCACCAACCAAGATTTCTTTTTCTAACTTCTGCTACTAAGTTTTTAAAAATTCCCTTTATGCAC CCAAGAGATATTTATTAAACACCAATTACGTAGCAGGCCATGGCTCATGGGACCCACCCCCCGTGGCAC TCATGGAGGGGGCTGCAGGTTGGAACTATGCAGTGTGCTCCGGCCACACATCCTGCTGGGCCCCCTACC CTGCCCCAATTCAATCCTGCCAATAAATCCTGTCTTATTTGTTCATCCTGGAGAATTGAAGGGAGGTCA AGTTGTTTGTCAATGATTTGTCAGAGAACCTGTTGAAATGTGAATTAAGAAGCTAAGAAAATATTTCTT AGCAACATTTTCTTTTTCTTTTTTTTTTTTTTCTTTTGAGACAGAGTCTCACTCTCGTCGCCCAGGCTG GAATGCAGTGGTGCGATCTCGGCTCTCTGCAACCTCTGTCTCCCGGGTTCAAGCGATTTCCTGCGTCAG CCCCAGAGTAGCTGGAATTACAGGCACACACCACCACGCCTGGCTAATTTTTGTATTTTTAGTAGAGCT GGGGCCACCCTGGCCCGGCCCCGTCTTCCTCCCCAAAGGTCAGACTGCAGGCTGCAGGGCTGTGCTGGA GGAGCCAGCTCTAGCTCACCCATGCTTTTGCAACAGGGTCGGGTTGGAAGTCAGCACAGGTCAGTCCTG CGGAAGGTTCCTTCGTGACTCATCTGTGAAGTGGGGTGGTTGGGAGAGGTAGCTGAGAGAATGCATGAG AGTCCTCGGTGCCTGGCAGGAGGCTGGAAGGTTCTAGAACACTGATGGTTATAAGAGTGGGACTGTGAG CCTGGGATCGGGGGGTGTGAGACTTGGATGGGAGCACAAGAGTGGAAACACAGCTTCTGCACGGAGCAG GCGCAGCCCTCAACACCCCGTGCACCTGCACCCTAGGGACTCTTGGGTCCAGATGTGCTGTGGTTTTCA CACCTTCTTGGGGGCAACAGGTTCCAGGAGCCACCTGTGGGTGCCACCTGAGCCACAGGCTCCCAGGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_181079.5
Synonyms	CD360; IMD56; NILR
Summary	The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]
Locus ID	50615
MW	72.5

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