MKRN1 (NM_013446) Human 3' UTR Clone

Specifications

Product Data
Product Name	MKRN1 (NM_013446) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	RNF61
ACCN	NM_013446
Insert Size	1514 bp
Sequence Data	Insert Sequence (showhide) >SC214833 3’UTR clone of NM_013446 The sequence shown below is from the reference sequence of NM_013446. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CTGGAAGATTTTTATGACTTGGATCTATAGCAACCTTGCGTGGCGTGTGAACTGGTCTGCTGACCTCAG ACAGCAGCTGTCCCCTGTGGTGGTGTGGCAGTGCCTGTGTTCTCTCCTAGGCAGGCCTCTCAACTCCAG GTGCTGTCCTAAGAATTTTTACCCAGGGCCTGTCTTCTCAACCCCTCACCTTTCCCTGAGGAGTGTGTT GTTTTCCCTGTTGAAAAAAGTTACAAAAATAAATCTTAAAGTTAGTTTTTTGTAACACGAATTTAACTG TCAGACAGTTAGTGTAGGTGTGTTGCGTCATCTGTTTTCAACCAGATTGCATTTATGGACTTTTCACAC ACTCATTTTGAGGACCCCAGGTTCAAAAGTAAAAGCAGTGGCCCTGCTTTGGGGTCCAAGAATAGGAGT GATGGGTGAAGGGACCTAAGCTGGCCAATAGCCCTCTGCCCCAGACATGGGATGTGGATCCTTGAGGTT TCTGGTGAAATCTGCACATCTGTGTTTTTATATCTGTTCCCTACCCTGTAATCCCTACCACGTGCACTT GTTCTGTGGTTTTGGTCTCTTGTTTAATTGCACACAAGTAATACTACTGGGTAACCAGAATCAGGTGTG AATGTGTTGAGATTTTTTACTGTTTTGCATGATAGGAAAATTGAGAAAGAATACGTATAAAAGATAGAG AGGCATAACATCAATGCAGAGTTGGAAGTTGGCTCCCAAGGGCTGACATGGTGTGAGTGTGTGGGTGTG TGATAAGCTTCTCATCCCTGCATAGATGCAGTATTCTTAGCCTTAGTAGAAAAACCTGGTTTAGTGGTT TAAGCCTTGTGTGGCAGATAGATCTTAAAGGGCAAAGCAGTATATTGGTAGTTGTCAATATAGCAGTGC TAGCTCTGTCTATATAAATAGAGAAATGGGGTTAGCCATAGAGGTTAAAACTACCTGGTTATCCCATAT AATAACACAAACTGGGTCTTGGATACACAGTTGTATTTAATGTTTTACGATCTAGCCTTTCCAGTACAG GCACTTTCTGAGAAACCTTTGTCCTCACTTGAGGCATTTTGTTGTCGGGTTTTTGTGTTTGTTTTTGTG GGTATTTGCCTCATTCCACCCCTGAGCTTTCAGGTAGACAGACGTGATTCAAAACTCTGTTCTAAGGTG TTTATTGTAGTGGAGTAATGGGTTTGCAGTGATAAGTCATACTTTTCCACCGAAAGGGAGGGCTTGGGA ATCCCTGAGATTAGCTAAAGTTAAGTTGTTGGAAGAATTCCTTGATTGGAAATTGTACCTTTGTGTTTT GTTGCTCTGTTTCCTGAAAATAACTCGGGGATGCTCCTGGTTTGTCCATCTACTGCTTTGATTCCTTGG ATCCCACCCATTCTTTCACTTTAAGAAAAAACAAATAATTGTTGCAGAGGTCTCTGTATTTTGCAGCTG CCCTTTTGTAAGAAGCACTTTTCCCAAATAAAACAATTAAAAAAAAAGTTGGCTGTTCTGTGTAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_013446.4
Synonyms	RNF61
Summary	This gene encodes a protein that belongs to a novel class of zinc finger proteins. The encoded protein functions as a transcriptional co-regulator, and as an E3 ubiquitin ligase that promotes the ubiquitination and proteasomal degradation of target proteins. The protein encoded by this gene is thought to regulate RNA polymerase II-catalyzed transcription. Substrates for this protein's E3 ubiquitin ligase activity include the capsid protein of the West Nile virus and the catalytic subunit of the telomerase ribonucleoprotein. This protein controls cell cycle arrest and apoptosis by regulating p21, a cell cycle regulator, and the tumor suppressor protein p53. Pseudogenes of this gene are present on chromosomes 1, 3, 9, 12 and 20, and on the X chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014]
Locus ID	23608
MW	56.6

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