ADAMTS4 (NM_005099) Human 3' UTR Clone

Specifications

Product Data
Product Name	ADAMTS4 (NM_005099) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ADAMTS-2; ADAMTS-4; ADMP-1
ACCN	NM_005099
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC214743 3’UTR clone of NM_005099 The sequence shown below is from the reference sequence of NM_005099. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CGGCGGCGCCCCTGGGCGGGCAGGAAATAACCTCACTATCCCGGCTGCCCTTTCTGGGCACCGGGGCCT CGGACTTAGCTGGGAGAAAGAGAGAGCTTCTGTTGCTGCCTCATGCTAAGACTCAGTGGGGAGGGGCTG TGGGCGTGAGACCTGCCCCTCCTCTCTGCCCTAATGCGCAGGCTGGCCCTGCCCTGGTTTCCTGCCCTG GGAGGCAGTGATGGGTTAGTGGATGGAAGGGGCTGACAGACAGCCCTCCATCTAAACTGCCCCCTCTGC CCTGCGGGTCACAGGAGGGAGGGGGAAGGCAGGGAGGGCCTGGGCCCCAGTTGTATTTATTTAGTATTT ATTCACTTTTATTTAGCACCAGGGAAGGGGACAAGGACTAGGGTCCTGGGGAACCTGACCCCTGACCCC TCATAGCCCTCACCCTGGGGCTAGGAAATCCAGGGTGGTGGTGATAGGTATAAGTGGTGTGTGTATGCG TGTGTGTGTGTGTGAAAATGTGTGTGTGCTTATGTATGAGGTACAACCTGTTCTGCTTTCCTCTTCCTG AATTTTATTTTTTGGGAAAAGAAAAGTCAAGGGTAGGGTGGGCCTTCAGGGAGTGAGGGATTATCTTTT TTTTTTTTTCTTTCTTTCTTTCTTTTTTTTTTTTGAGACAGAATCTCGCTCTGTCGCCCAGGCTGGAGT GCAATGGCACAATCTCGGCTCACTGCATCCTCCGCCTCCCGGGTTCAAGTGATTCTCATGCCTCAGCCT CCTGAGTAGCTGGGATTACAGGCTCCTGCCACCACGCCCGGCTAATTTTTGTTTTGTTTTGTTTGGAGA CAGAGTCTCGCTATTGTCACCAGGGCTGGAATGATTTCAGCTCACTGCAACCTTCGCCACCTGGGTTCC AGCAATTCTCCTGCCTCAGCCTCCCGAGTAGCTGAGATTATAGGCACCTACCACCACGCCCGGCTAATT TTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTTAGGT GATCCACTCGCCTTCATCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGTGCCTGGCCACGCCCA ACTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGCTCTTGAACTCCTGAC CTCAGGTAATCGACCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCACGCCCGGTA CATATTTTTTAAATTGAATTCTACTATTTATGTGATCCTTTTGGAGTCAGACAGATGTGGTTGCATCCT AACTCCATGTCTCTGAGCATTAGATTTCTCATTTGCCAATAATAATACCTCCCTTAGAAGTTTGTTGTG AGGATTAAATAATGTAAATAAAGAACTAGCATAACACTCAGCATCTAGTAAGTGCTCAACAAATAGCAG CTGCTGTTACTTACTGTTATCAAATTTCTGTCCACATCCACTCTCCATATGCACTTGAAGGTGGCAAAG ATCCACAACCATGGTGCCTGCCTTTATCCTCAGGGTCCGTTCCTTTGGTTGGCAGACCCCTATCCTGGG TTCTGAGGGACCAACAGAGAAAGGAAAATTCCATCCCTCACCTCTGGAAGTTCCCAATCACAGGAAGGA AACATAGTAAGCACGTGGCTACAAATACAATTGACAAGAACATGAAGGTGCAGGATAACAAGAACAAAT AACAAGAACAACTGCATCAACACAAATGAGTGCTTAGTAATAAGGGTGATAGTTGAGGGGTCTGGGTTT CACAACAGTAGAAAGAGCACTGGAGTGGGAGCCAGCGGGTCTGGATTCAATTTGGGGCTCGGCGTCTTA TTAGCTGGGTGGTGTTGGGTAAGTCACTGATGCTGAGCCTTAGATTGCTCATATGGGACTAACAGTATC TACTCCCACAGAGTTGTTCTGGGAACAAATGCTAGAATATTTTCAAAATAGTAAAGGTTATAGTCATG ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_005099.6
Synonyms	ADAMTS-2; ADAMTS-4; ADMP-1
Summary	This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The expression of this gene is upregulated in arthritic disease and this may contribute to disease progression through the degradation of aggrecan. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
Locus ID	9507
MW	74.1

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