Stromal interaction molecule 1 (STIM1) (NM_003156) Human 3' UTR Clone

Specifications

Product Data
Product Name	Stromal interaction molecule 1 (STIM1) (NM_003156) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	D11S4896E; GOK; IMD10; STRMK; TAM; TAM1
ACCN	NM_003156
Insert Size	1440 bp
Sequence Data	Insert Sequence (showhide) >SC214586 3’UTR clone of NM_003156 The sequence shown below is from the reference sequence of NM_003156. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AAAATCTTTAAGAAGCCTCTTAAGAAGTAGGCAGGATGGGGTGGCAGTAAAGGGACAGCTTGTCCTTCC CTGGGTGTTCTGTCTCTCCTTCCCTCCCTTCCTTCAAGATAACTGGCCCCAAGAGTGGGGCATGGGAAG GGCTGGTCCAGGGGTCTGGGCACTGTACATACCTGCCCCCTCATCCTTGGGTCCTTCATTATTATTTAT TAACTGACCACCATGGCCTGCCTGCCCTGCCTCCGTCCCAACCATGGGCTGCTGCTGTCACTCCCTCTC CACTTCAGTGCATGTCTTAGTTGCTGTTCCCTCAGCTCCCAGCTCCACCTCTGGGGTTCAGCTTCTGTC TCTGCTGTCCCAGTTTTGAGGTTTGGTTTCTTGTTTCTGTCTCTTGCTTTCGGGCTCCTCCCTCCCACC ACTCCCCAACTTCCCCTAGCAGTTGCAGGGAAGATAGGACGAGTAGCTTCTGACATGTGTGCCTCAGAT CTGTTCCACCCCACTCACAGTGGTTCTGTTTGCTCCAGACTGGGGCTAGGGCCTAATCTTTGAAGTTTG TTCTTTGGTATTGATGTGGGTCAGAAGGAGCCTCATCCTAATCTCACTCAGGCCTCCAGGGATCCATGG GGGAGTGAAACCAATTCTCAGAGAACAACCCACCAGAGACTTTTAAAGAGAGGCCAGGCTTGGGAATGG GTTGGGAGAGGCATCTGTTCATTGGAGCATGAGTGGATGCCAGAACTGTAGGTTATAAGGCAGTCACTT TTTCTCTCTACTCCCACCCACACCTGCCTCCCTCTTACCCCTGCTCCCCCACACTGCAGGAGGATTTGT CTCTAAGAGGTGCTGCCCCAAAGCTCCCCAAGCATCAATACTCCTAGGGCTCAGGACAAGTGGCTCCCC TGGCCAGGAGAGCCACAGCCATGATACAGGGCTCTTATGGAGCCCTGGAGTTGTTGGGCAAGGATGCTG TCATTTTTTGAACCAAAAGACAAACAGGTTAAAAGGAAAAAAAGTAATCTGAATTTCCCAAGTGCCTAC GCTGCATATTCCCCTTGTTAGATCCCATTTTCATGTTACTTTGTAGCCTTGGCCAGAGGCTCAAAAAGG ACACAACCAGTTTGGGGAAGGGGTGGCTAAGGAAGATGGTATAGGTGAAGGCGGCTGTGTGACCACTTT CCCCCACCCTTCCCACCCTCTAGACAACTCTCTCCCTTACCTGTTTTTGCTATGGCTGTAAAGGTATTT TTCCTCTGCCCCACTCCCTGCCATACCTTTATCCTGGGATCCTATTTTGGGCCTGGGGTGGGTATACCT GGGGCTGGTCTTAGGAGGGTGCTAGGCTGCAGACTGCCTTGTACTCCCTGGACACCCTCAAATGGGGTT TTCTGTGTTATTTCATAAAATTCTTTGAAGTCCAATAAAGCATGTAGGAGATTTTAACCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_003156.4
Synonyms	D11S4896E; GOK; IMD10; STRMK; TAM; TAM1
Summary	This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. Mutations in this gene are associated with fatal classic Kaposi sarcoma, immunodeficiency due to defects in store-operated calcium entry (SOCE) in fibroblasts, ectodermal dysplasia and tubular aggregate myopathy. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6 kb from the 5' end of the RRM1 gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]
Locus ID	6786
MW	52.9

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.