TMED2 (NM_006815) Human 3' UTR Clone

Specifications

Product Data
Product Name	TMED2 (NM_006815) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	p24; P24A; p24b1; p24beta1; RNP24
ACCN	NM_006815
Insert Size	1883 bp
Sequence Data	Insert Sequence (showhide) >SC214455 3’UTR clone of NM_006815 The sequence shown below is from the reference sequence of NM_006815. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AGATTTTTTGAAGTCCGGAGAGTTGTTTAAAAAGCCTCTTCCTGATGATCCCAACTCAGAATTCACTGT TTACCAAACACCTTGGTCATAATAATGTCATTAGTTTCTCCATTTTTATTTTCTGAACTGTACATTCAC AACTTATGTTTCTTTGAGATTAATAGATATTGGGGGAAAAACGCCTTTTTAGGAAAATTATAGTGAAAA TTTGACAGTTGATTGGCATAATTTCTTGTTTGAATGCTGCCTCCATTATATAGGTCCTTCCAGGAACTC AAACACTGTAAGTGAAATATGGGAGTATAGTTTTTATTATTTCTTCTTTTCCTTTTGTTTTCATAATAT AATGCAGTTTGTTCAGGAAATCAGCACAAAGCCTGATAGTACTTTACTAAAATGACTGCATTCTTTGGA TTCCTTCAGTCTATGGTTCAAGTCACTAAAGATTCATTTTTGTTGAGTCCTTATGAGAAACAGCAGTAT GAATCTTGACGGTTTCTGCCCGTCCTAATGGCAGAGCTCTCTGACTTGGGTGTATGCTGCCAGGCTGGG TACTTTCATACTTTGTTTTCTTGTTTTGCTTTAAAACTACGACTCAGCATACATTTTCCCACATACATT TTTACATTGTACCTTAGGACTCAGTCATCTCCACTTAAATTGATGACACAAGCAGCTAATAACCATTTC TGGGTTTCTGCCTAACCCCCTAATTGTCTGTTAAAGCCAATTCTCTGGGTGTCCCAGTGAGTGGTGGCT TTTTTTCTTTCCACATTGGCACATTCACTTCTCCCACTCTTGGCATGTAAGAAATAAGCATTTACATAA TTGGAAAAATCTGGATTTCTGATGCCAAAGGGTTAAAGCTTCTTGGATTTCATTTCATTGATATACAGC CACTATTTTATTTTTGATCAGTGGCCTTTGGGCCACTGTTCAGGGTACTGACCATCAGTGTCAGCATTA GGGTTTTGGTTTTTGTTTCTTTTGGGTCTTTCTTTTTTGGCACATGTGAATCTTGTTTTGTGTAAAATG AAATTACTTTCTCTTGTTCTCTGATGATGGGTTTAAAATTAAAAGAGCATCCGGTTTTGGTATGGGGAT GATCCAGGATTATGTTGTGACTGATACATATTAGTTACTTGTGCTTTTTTTTTTTTTTTTGGATCTTTG CAAGGGCAAAACTACAAGTAACGAGTTTTATATAATTAATTTAAATTTGTTACAGGTTTTCATGTTCAG GATAAACCATACTTCCACCTTGGGTGAGAACACTTGCAACAGTTTATTAATGAGGTGACTTTCACCTTA GGACAACTGTTGCATGCCAAGTTTTTTGTGTGTGTGAAACACTTCAAAACTGATTTAAAAGATGTAAAT TTAAAATTGGTTGTATCTAATATGCCCCAGGTTCGGTAAATAAACAATTCTTTTTAAAAACAGTATTCT GTGTTTTATATATTGACAGCTAATCCACATTTTTTACACACCAACTTTCTGTTCTTATTTGACATGAGA CATGTTCATGTTTTCTGAGTATTTATACCTATTACGTCTGTTACTTTTTAATTCTATAAACTTGAGGAT AGTGAATGGTACCAAGTTTTAGTTTCTGCGTAGGTTTTCCAGTGTGGCTTCTCTGATGGATCAGTGCTA AAATCTTAAGTATTTTTCTATTTGGGAAAAAAGGGTTGAATTATTTTCACTTGCCCACGTAGTTTATGA ATGTGGGAAATAGCTTCAAAGACAGATTAAATGATTTGCCCAAGGCCACAGAAAAGAGTGAAAGGTGGA ACCGGAGACTAGATCACCACCTGTAGAAACTGTTCTTCCTCTGTGAAACTAACGGCCTGCTGGTAATAA AAGTAGCTACCATTTCTTGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_006815.4
Synonyms	p24; P24A; p24b1; p24beta1; RNP24
Summary	Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway but also in post-Golgi membranes. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side. In COPII vesicle-mediated anterograde transport involved in the transport of GPI-anchored proteins and proposed to act together with TMED10 as their cargo receptor; the function specifically implies SEC24C and SEC24D of the COPII vesicle coat and lipid raft-like microdomains of the ER. Recognizes GPI anchors structural remodeled in the ER by PGAP1 and MPPE1. In COPI vesicle-mediated retrograde transport inhibits the GTPase-activating activity of ARFGAP1 towards ARF1 thus preventing immature uncoating and allowing cargo selection to take place. Involved in trafficking of G protein-coupled receptors (GPCRs). Regulates F2RL1, OPRM1 and P2RY4 exocytic trafficking from the Golgi to the plasma membrane thus contributing to receptor resensitization. Facilitates CASR maturation and stabilization in the early secretory pathway and increases CASR plasma membrane targeting. Proposed to be involved in organization of intracellular membranes such as the maintenance of the Golgi apparatus. May also play a role in the biosynthesis of secreted cargo such as eventual processing.[UniProtKB/Swiss-Prot Function]
Locus ID	10959
MW	72.7

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.