JNK2 (MAPK9) (NM_001135044) Human 3' UTR Clone

Specifications

Product Data
Product Name	JNK2 (MAPK9) (NM_001135044) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	JNK-55; JNK2; JNK2A; JNK2ALPHA; JNK2B; JNK2BETA; p54a; p54aSAPK; PRKM9; SAPK; SAPK1a
ACCN	NM_001135044
Insert Size	1408 bp
Sequence Data	Insert Sequence (showhide) >SC214189 3’UTR clone of NM_001135044 The sequence shown below is from the reference sequence of NM_001135044. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CGCGACCTTGGCCCCGCCATGCTTTCTTAATGCCTCAGGCAGCATGACCACCTGCTTACACGAGCGCTC ACGAGGACAAAGTCGTAAAATCCACTCCAGACTGTGTTCTAAGGGGGGCTTTACTGTATTTGTTAATTA GTGTCACAAGCCAAGTGGTTCAATTTCATTCTTTATTTTTAACTTGACTACCTGTGATGACTTTGAGAC TTAGAGTTCAGTTAAACCGATTATATTAGCTCTTAATTTTGCCAAAAATAGCTGGACACATAGAAGAAA TTATTTACTCTTTGATAAGTATATTCTGATATTTAAATGAAAATACTGTATTATTTAGTTTATTCCGTT AATTTAACTAGGAAAGATGCTATCTAAATTTAATAGGCTAGTGTGCTTGTGTGCTTTAATTAAGTACTA TTTTGTTAGTTACTGGTATGCATTGAAATATTTTCCCCCAAAGTAAGAACTGAAGCACATTACAAAGGA CCTAAGTGAAAGAGATTAAAATGAAAATTTTGTGAGGAACAATATGTTAAACTTTCTTGTTTGTTACTG TGCTGACATTTTGTAGAATTTTTTTTAAAAATCTGTCTAGTGGGTTATTTTGTGACACACTGGGGAAGT CAAAATAAATGTAAAATGAAAGAGATAAACTCATACTGTAGTCAGCAAGTCATGTTAGAGATACAGCAG AAAGGAGAATAACTACTCTAATTGTTACAATAGCCTTCTTTCCTCATTTGCCATTCTTCCATCCTCAGT ATTTTTTACCCTAACATGGTTCTTCACATCTTCCCTTTTTCATTTGTGTTTTAACCACTTAGTTTTTCA TTAGTCTTTGACTTTGTTTTCGTTATGAAAGTTTAAATTGGTCTCCATCCTTGGGCAGATTGATGGTTG CTTTTAAGGAAATCAAGCTCCATAGTCAGTGTTTTGTATGTATCTTAGGAAAATAATTTCAGATTTTAA TAATTTTATCAAAGTGGTCTCCTTATAAATTCTTCACAGTGCAAACTTAAAGTGAAAATATTTTTATTT CTCTCATTTTATTTACCTTTCTTTACATTTTCTATATCATAGATTATATAATATGTCAAGTTATTTTAT TTGTTCTACTAAATTTTCTAGCAGTTTCCATAGCCTCATCTCAGATTCACTTGTTGCAACCTATAAATA AGGACGTCTTTATTTTGCAAGTAAACTTAATTAAAAAGGGAAAAGTTGAAAAATTAAAAGACTAATAAT TTAGAAATATCTACTTAATGTTCAGTTTGTCTCAATTCTTACTCATTTTGTGCCATTCCTTGTTTTATT ACAAAATGTTTTCTTCAAAAAGTACAAAAATGAAAAATGTGAGTACTTTTTGGTGCATTTTAGTAAGTA AAATTAAAATTCCTGCTATACATATGAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001135044.2
Synonyms	JNK-55; JNK2; JNK2A; JNK2ALPHA; JNK2B; JNK2BETA; p54a; p54aSAPK; PRKM9; SAPK; SAPK1a
Summary	The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Sep 2008]
Locus ID	5601
MW	55

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