RAB8A (NM_005370) Human 3' UTR Clone

Specifications

Product Data
Product Name	RAB8A (NM_005370) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	MEL; RAB8
ACCN	NM_005370
Insert Size	1960 bp
Sequence Data	Insert Sequence (showhide) >SC214076 3’UTR clone of NM_005370 The sequence shown below is from the reference sequence of NM_005370. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AGCAGCTTTTTCCGATGTGTTCTTCTGTGAGGAACACCGCCTTACTCTGAGCCTCGCTCAGCCCAGCTG ACTGTGCCTGTTCTGAGTGAGCCCCTCACTCAGCCGGGGCCCTCCCACCTCCAACGCCCCGCCCACGCC GCGGCCACCGGGCCCACGGCCACCAGAATGCAATTGAGAAATCGTTTATTTTAGTAACTGTCTGATCTT TTTCAACTTTGGAGATGGAATAAGTTAAAAATTTGCTATTTTTCCTGTAACATCTGCTGAACGGGCCCA CCCACACGTTGTATATTCAGAGAGAGAGAGGGAGTCAAGGTGTGACCGTCGACCACAGCCAGTGTCAGG CCTCTGCCTCTGGGCCTTTGCTTTGTGGCCTCACTGCAACACAAAGCTCCACCAGGAGGCTGGTTCACG TCCCCTACCACGGAAGCGAGGTCCCAGAAGGCCAGCGGTGGTTCCAGGAGCAACAGCTCCCAAACCCTG AGCAAGGCAACCGATCGCCAGGACCAGGAAGCATCACCCAGGAGATTTGGCGCCCACTTCCACCTCTTC TCTCAGTTTTGGACAAGTGACAAACCATTTTGCCCCCTCACTCTTCTTTTTTAACTGTTAAACCAAAGG AAAGCACAAATGAAGGAAATCCTGTGTAAAGCATTGAGAAGGAAAGAAGCCTGGAGCAGCCTCTCCTGT CCACAGCCAGGGGTTAGGTCTGCAGGCCCGTCTGCGGTCCCCATCGAGCATCAAGGGGACGCTGTGTGT GCTGCAAGTGACCCCGAAAACAACCACAGCCGTCACATGGTCCTCCTGAAGTTGGGGCACCCTCCTCTC AGCACCAAAATGGCCCCCACTCCTTCGTGTCCTCCCGCTATCTCCAAATCGGACGTTCTTTCTAGCTGA GATTTTTATTTTTCCACATCTGTAGTGCCATGAAGCGATTCTGTCTTTGACTTCCAATGGCAAACCTGG GTGATCGGGAACAAGCACGTTGTACCCTTGGCTGGACATGGCCAAGACACAAGGCATTCCACGGCGGCA AGCTGACCGCACAGCAGTCTGGCTTGATTTTCAGCCGTCATCATTGGGTTCTGTTTTGACAGCTCTGCT GTCCCATAGGGACTGCGACTGGGACCAGGTCAACCACGCCAGGGGGGTGTCACCAGCCTTTTCTTTTTT TCTTTCTTTTTTTTTTTTTCCTCCTTAAGCTGCTGTCAATCCAAACCATTGGCATCATCGTTTCTTTTG AATTAAAACCAACATATCAGCAATAGTCTGCTCTCCCCGGGAATCTCTAACATGCTCTGTTTACATCGA TAAATGCACTTAAGGAAAACAAACAAATTAAAGCTCATCTTAAAGTCCAAGGATTTTTATGTCCACATT TTCCCTGTAGGCCACACGGACATGGCCAGGTGCTGGGGGTGGGTCTGGACAAGATGGTAGAGCCCATGG ATTACCCCATCGAGCGGCCACCTCAGAGGAGATGCCACCCATCATCAAAAGACTAAATTGGGAAAAGAA GCCTCCTGGCTTGGTGCAGTGGCTCACACCTGTAATCCCAGCACTCTGGGAGGCCAAGGCGGGCTGATC ACTTGAGCTCAGGTGTTCGAGACCAGCCTGGCCAACATGGTGAGCCTGCGTCACCTGGCTTCTGGCACA CAGCTCGGCCACTGTGTCCCTCCTGCCTCCCTGGCAGGTCCTTCTAGGGGCCCTCTCCTGGCTGGCTTT CCAGGGCATTCCTTCCACTCTATCCAGGGTCCTTCCCAAGACCACACCCAGGTCCAGTCATTCCCTAGG ACTTGGCAGAGAGCTGTACTCACAGCCAAGATCACAGCAAAATCAGCAAAGGGAAAAGGCATGCAGAGT GAAGTCCAGAGGCAACCAGACAGAAGCATCCAGAATCCTCTCACAGTGGGGTCACACACCCCATGCTTA ACTCCCCCAACAATGAGTTGTAACAACA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_005370.5
Synonyms	MEL; RAB8
Summary	The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1. [provided by RefSeq, Jul 2008]
Locus ID	4218
MW	71.5

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