Bestrophin 3 (BEST3) (NM_152439) Human 3' UTR Clone

Specifications

Product Data
Product Name	Bestrophin 3 (BEST3) (NM_152439) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	VMD2L3
ACCN	NM_152439
Insert Size	1328 bp
Sequence Data	Insert Sequence (showhide) >SC213891 3’UTR clone of NM_152439 The sequence shown below is from the reference sequence of NM_152439. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AACAAGGAAACTGAGGAATCACCCAAATGAGTGCCACCAAGTTCTAGGACCTGGTTCTAGCCTAGATTC TTACCTCCCCAAAAGCAGCATATTAGGCCCAGGACATACCTGAAGGCTGGTCGACTTTTTAAAAAACAT GATCACACTGTATAAGCTACTTAGAACTTTGAAGGGCATTATGATCCTGACTTTTTGAGAGCTGCGAAA AATCAAACGCATTCACGTCATCCAACACAACATGGCTTTCATCAGAAGTTACACAGACCACAGTGATTT AGCCAAATAAGTCTTAACCAAAAAAAGGAATCTGAAAAACATACATGACTTATAAATTCATAGATTATT AGTTGTGGAAAGAGTCTCATAGATCATAGTCCAATCCCCTAGACCCAAAGGCCCAGACACGCAGGGTTC TCTATTTCTCTTCTTTTTTCTCTTTCTTTTTTTCTTTAGCCATAAAGAAAGGAGATGGATCACCTAATG CCTGAAAGATCCCCTCCTTCCTAACGTTTTTGTTTGAGGCTTTCTAACCATCTCATTCCTACTTTTATA ACTATTATTGTTATTATCACTTCCTGATTCTTAAGCTTCATCAGCACCAGAACACTTAATTCTCTTCAA TTTCCTTTTTTACTTTTCTCTCTTTTCCTTTTATTCTGTCATCCTTTTTTTCCCTTCCCTTCTCCCTGG TTGTGCTGCTTTTCTAGTAATCTGTCCCATTTTTCAGGTTATAATATTTCCTCTTGCCAAATCTGTTGC TTATGTCTTGCCATGAATTTCAAAATATAAGACATTGGCAAAGCCTCCTACAGAATCATCAAAGGTGTC AACAAATCCAGCCTGATACCCTTCCAGTCTCACTTCCAGTGGAAGGCATATAGGAGTGATGGTTCCCCC CGTGCCCTTGCAGCCATTGACATTTCTTTCTGCTTCCACTATTTGGTGTTGGGCACTGGAGAAAAACGA AGCCAAGAGAATATGAAATTTGCATAGCCAAATGCTATGGAACCAAAGAATAAGATGACTCACATCTGT TTAACTTGAACTCTTATGCAAAAATCCTAATCGTGTCGCAACACGGGACCAGTTACTGTGTCTATCGGG TCATTTGGGAATGGGCAGGATACTGGAGCTGGGAGGCTAATGGGGTCCAGAGCTGCATAATGGGGATCG GATGTTGGTACTCCTCCCAGGGAGCTCTCAGGACAGCTGTTTGTCGTGGGCTCCCAAGTGCCTAGGCCA TGCCTTACGACTGCTGCACTTACCATTTGTCATATGATGGCACTTGACTACATATGGCTTTAGAAATAA AATAACCCTCAAAACTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_152439.4
Synonyms	VMD2L3
Summary	BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (MIM 607854), the gene mutant in vitelliform macular dystrophy (VMD; MIM 153700), and 2 other BEST1-like genes, BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length (Stohr et al., 2002 [PubMed 12032738]; Tsunenari et al., 2003 [PubMed 12907679]).[supplied by OMIM, Mar 2008]
Locus ID	144453
MW	50.2

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