SH3BP5 (NM_001018009) Human 3' UTR Clone

Specifications

Product Data
Product Name	SH3BP5 (NM_001018009) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	SAB; SH3BP-5
ACCN	NM_001018009
Insert Size	1763 bp
Sequence Data	Insert Sequence (showhide) >SC213485 3’UTR clone of NM_001018009 The sequence shown below is from the reference sequence of NM_001018009. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GCTGACATAAAAATGGTGCAGATTGGCTGATTCATCCTGGGCCCTGGCCGATGTGCATATCAACATTTA TACATGGAACTGGAGAACATTGTGCCAATAATCATTTAATATATGCCAAATCTTACACGTCTACTCTAA ACTGCTCTAATGAAGTTTCAGTGACCTTGAGGGCTAAAGATTGTTCTTCTGGGTAAGAGCTCTTGGGCT GGTTTTTCAGAGCAGAGTTCTTGTTGTGGGTAGACTGTGACTAGGTTCACAGCCTTTGTGGAACATTCC GTATAACGGCATTGTGGAAGCAATAACTAGTTCCTATGAAAGAACCAGAGCTGGGAAGATGGCTGGGAA GCCAGGCCAAAGTGGGGGCAACAGCTTGCTTCTCTTTCTCTTCTCACCCTCAGTTTGTATGGGAAAATG GAGATGTCCTCTCCACTTTATCCCACGATATCTAAATGAAAAAGAAAGAAAACCCACACACAAAGCAAA AACTCAAGTATTAAGAGCACATATTTTTGACCCAGTGGAGGCTTAAAAAAAAAAAAATCCAAGAACACA ATTCATTTTCACCACCTCTGGTGTTCAGAGGGGGCTTTTAAAAAAGCGTGTATGCTGGGATACCCATTA AAACCATTTTCTAGAAGGCTACCATGAGCTGCACTTTTTGGGGTGGGAAAGGTGAATGCCAGTGGGGAT GCGGGGGGATGAGGGTAGGAGGGACTTATAGAAGGGGATTTGTGGCTGTGGGGGAGAAGGTTCTACAGC ATAAGCCTTATCCTGCCAGCCAAGGGGATTTATTCTAAGAGAAGTGCATGTGAAGAATGGTTGCCACTG TTATTAGATTGACAAGATGTTAATTTCTCTGTAGGTTGTAACTTTAAAAATAAATGAAATTATTTAAGG GTTATGCTGCACTAGTATTCCTTAGAGGAAACAGTTCTTTAAAGTTAGGAAAGGGAGTAGGCAGGCATG TGTTGGCAAAGGCTGTTAATAGTAGTTAAGTGTTAAGACTGCTTTTCTTTAACGTTTTCATGGTAATGC ATATTTAGAGCACTGTATTTTTGTCTTGTTAAGAAAATTTAGCATTTCTAAAAGAAAAAAGCAACCCTC TTTCAAACTGTTAATTCTGTCACAGCCTGTATATTTTAGTCATTTGTAAATCTCTTCATACAATAGTGA CTTCTTTTTTGACTGATACAGTATCTTAATTACAAGGTTATTTTGTACTTGTCTTAATACACTAAGTGT AATAAAAACGGCTTGAGAAAAGTTTCTCCTTTCTGTGACTTCAAATAAGAACTCCCAGTATTGCCTAAA TCTTCTAGGCAACCCTTTTTCCATAAGGAAGAGCATGGAGTGCTGTGGTCACCAGTAATCATTTTCAAT TAATTAAGGTCATGAACAGTAATAATTTAAGCCTTGTTTACCAAGGTTTGAATTCTACTTTTGCTGTTG CTAAAGCTGTGGGCAATGAGGAGACACAGTGGCAGATAAAGACGAGGTGGTGACGCTGGAGGAGTGGGC CTCGGCTGCACACTGCAGTCTCGAAGCTTAAGTGTTGCTGTCAGTCAGTTCTCATCCCCAGAGAATTAT TTAATTAATTAACTGGGGGGGGTACACTGGGGCATTAGACTTTTAAAAGCTCCCCGAGGGAATTCAAAT GTGCATTCAGAGTTGAGAATCAGATGGATTCTTTCTTTTGTGGAAATGTTTTATAATATTGGACTCTTA ATCCGCATTTCATTATTAAAGCATGCTGTGGAGAAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001018009.4
Synonyms	SAB; SH3BP-5
Summary	Functions as guanine nucleotide exchange factor (GEF) with specificity for RAB11A and RAB25 (PubMed:26506309, PubMed:30217979). Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.[UniProtKB/Swiss-Prot Function]
Locus ID	9467
MW	66.9

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