ALDOB (NM_000035) Human 3' UTR Clone

Specifications

Product Data
Product Name	ALDOB (NM_000035) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ALDB; ALDO2
ACCN	NM_000035
Insert Size	1279 bp
Sequence Data	Insert Sequence (showhide) >SC213471 3’UTR clone of NM_000035 The sequence shown below is from the reference sequence of NM_000035. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TCGCTCTTCACAGCCTGCTATACCTACTAGGGTCCAATGCCCGCCAGCCTAGCTCCAGTGCTTCTAGTA GGAGGGCTGAAAGGGAGCAACTTTTCCTCCAATCCTGGAAATTCGACACAATTAGATTTGAACTGCTGG AAATACAACACATGTTAAATCTTAAGTACAAGGGGGAAAAAATAAATCAGTTATTGAAACATAAAAATG AATACCAAGGACCTGATCAAATTTCACACAGCAGTTTCCTTGCAACACTTTCAGCTCCCCATGCTCCAG AATACCCACCCAAGAAAATAATAGGCTTTAAAACAATATCGGCTCCTCATCCAAAGAACAACTGCTGAT TGAAACACCTCATTAGCTGAGTGTAGAGAAGTGCATCTTATGAAACAGTCTTAGCAGTGGTAGGTTGGG AAGGAGATAGCTGCAACCAAAAAAGAAATAAATATTCTATAAACCTTCAGCTGCTATCGGGTTTCACTT TTCTGCTCTTGCTGTCCAAAGACTCAGTGTATTTCATTACTTTTGACTCTACTAGACATGACTGGGTTT CAACAGTAAAGGTCTTCAACTCTTGCTAGTCATTGGAATCAAGCCGCAAAATTTTAAAAACTGAGATGC TCAGGCCACACCCCAGCTCAATTAAATCAGAAACCCTAGACTTGGGATCCTCTAACTATTAGATTTCTT AAAGCTCCCTCAGTAATTCCAATGTACAGTCAAGTTTGAGAACTACCAATCTAAATTTCAAGTTTGAGG GTATTTGAAAATTAAAGCCATTCACAATACGAAGCCAGCTAAAAATGTAGAATGATTTTGAGCAACTTG TGGAGTATAATAAGAGAATTAATGTGACTTCAATGCTTGGAGCATTCTTGTTCAAGTGGCCCAGGTTTG GTGAAACAGGACTACCTTGTCATCTGCACGTCCAGGCATATTTCGTAGTTTTGCAGTAAATAATATTCA CATAATGATACTGTATTGACTTTCAATTTTCAGAATTAACCTATAGTTACAGCACTTAAGACAACCAGA GTTATAAAAGAGAATTTAAATATTATAACTTTGGACAATATAAAAGTGATGATTTAACTGACAGAAGCT AGGAAATATAAGGGGGAGGAGAAGTGGAAGAAAGCAAAGAGAGTCAGGAATACTACTTAAAACTGATGG GTTAAGAAATAGTGCTTTAATTCTATTTAAGTAATAAAAGAAATGGATGTAAATCATAAAAATATATAT CTAAAATTAAAATATTGATGGTAGTATGCTAAATTTC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000035.4
Synonyms	ALDB; ALDO2
Summary	Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance. [provided by RefSeq, Dec 2008]
Locus ID	229
MW	49

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