MAPKAP Kinase 3 (MAPKAPK3) (NM_004635) Human 3' UTR Clone

Specifications

Product Data
Product Name	MAPKAP Kinase 3 (MAPKAPK3) (NM_004635) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	3PK; MAPKAP-K3; MAPKAP3; MAPKAPK-3; MDPT3; MK-3; MK3
ACCN	NM_004635
Insert Size	1275 bp
Sequence Data	Insert Sequence (showhide) >SC213446 3’UTR clone of NM_004635 The sequence shown below is from the reference sequence of NM_004635. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TCTGCCTCACAGGGCTGCAACAACCAGTAGCTCATGGGGCCTTGGAGGAGCCTGGCCTCTCAGCCTGCA TAACAGACTGAAATGTGCTCAGGCCCTGGCCAGGAGGGCCCAGGGTCATTCTTTTAACAAAAGGATTAT TTTGTTGTGTTTTAATTTGTCACTCGGAACTTCAGGATGGAGGACCCTGACCCTAAACCTCCTTCAGAT CTCTGGCCCAGGCTCAAGCCCTAGAGATGGGCAGGGCCTAGGGGCTGGGAGCTGCCTGCTGCCATAGCA GCACCTTTAGCTAGGTTGGCCCGAGTGAGGCCTCTGTGCTGTCCTGCCCTGGTGCATGGCCTTAGCTTT CTAGGCCACTGGGAGTTGTGGCTGGGCTTCCCATCTTCCACAGAGACATCTCCCTGTGGGATGGGCAGA TGGGCCTGGCCTTGAGAAAGGCATTGGCCATTGGTTGCCATGGTGACCAGGGACCACGTTGCTGCCTGT GAATGCTGAGTGAGCGAGTAAGGGAGGAGGGGCGATTGAGGGTTCACCTCTGCCTTGGGGAGGCTGATT TCTCACACACTGGCTGGCCCTCTCATTCTCACTCCTCCTTGGGCCCTGAGGCTGCTGGATCCGGTCTGC CTGCCTCCCTGTGCAGTCCAGCCCTGCCTTGCTGCAGCCCCAGCCCAGATGGCACTCAGCGCTCTCCCC TGAGGGAGTCCCTGGGCCTAGCCATCCCCTCACTATTCCCGACCCAAAGGGTGACTTTTCATCTGAACT TAAGGTGGGAGATATTTTTAACTTTTTTCCACTTTGGAAAATGTCACTGTGACAAAAGCCAGCATACTT TCCCTGCACCCATCTGCTCACCAGATCTCAGGCAGGAAAGCCCCTCTCTGTTGAAGTCAGGGGCTATCT TTTGGTATACTTGTGTGAAAGTGGCTGGTTGGGAGCAGAGCTAAGTGGCTTCCCATTAACCTGAGGTCT CTTTCTTTACTCTGGGTCAGACCTGAGGTTGGGGAAGGCGACTGAGCCATGCTCAGAATGTCTGGTCCT GGCTTGGGCCTGAGTAGGGCAGAGAGGGCCTTTCCTGGCTGATCAGAGCTTACCAGCCCCACCCCACCA TGGTAGCCTTAGGGTGCTGAGTGCCTGATACTGCCTGACAAGTGCCTGACACGCAGCCTAGTTCCTTCC TGGCCCCTCTCTCACTGGCTGGGAAACCCTAGACCATGTCAGATAGGACAACACTGCTGGGTTTTACAT CCAGATAGTAATAAACACCATTTCATCATTTTC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_004635.5
Synonyms	3PK; MAPKAP-K3; MAPKAP3; MAPKAPK-3; MDPT3; MK-3; MK3
Summary	This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011]
Locus ID	7867
MW	46.8

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