LEF1 (NM_001130713) Human 3' UTR Clone

Specifications

Product Data
Product Name	LEF1 (NM_001130713) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	LEF-1; TCF1ALPHA; TCF7L3; TCF10
ACCN	NM_001130713
Insert Size	1240 bp
Sequence Data	Insert Sequence (showhide) >SC213362 3’UTR clone of NM_001130713 The sequence shown below is from the reference sequence of NM_001130713. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GGTCCAAGAATGACAGCTGCCTACATCTGAAACATGGTGGAAAACGAAGCTCATTCCCAACGTGCAAAG CCAAGGCAGCGACCCCAGGACCTCTTCTGGAGATGGAAGCTTGTTGAAAACCCAGACTGTCTCCACGGC CTGCCCAGTCGACCCCAAAGGAACACTGACATCAATTTTACCCTGAGGTCACTGCTAGAGACGCTGATC CATAAAGACAATCACTGCCAACCCCTCTTTCGTCTACTGCAAGAGCCAAGTTCCAAAATAAAGCATAAA AAGGTTTTTTAAAAGGAAATGTAAAAGCACATGAGAATGCTAGCAGGCTGTGGGGCAGCTGAGCAGCTT TTCTCCCCTCATATCTGCGTGCACTTCCCAGAGCATCTTGCATCCAAACCTGTAACCTTTCGGCAAGGA CGGTAACTTGGCTGCATTTGCCTGTCATGCGCAACTGGAGCCAGCAACCAGCACATCCATCAGCACCCC AGTGGAGGAGTTCATGGAAGAGTTCCCTCTTTGTTTCTGCTTCATTTTTCTTTCTTTTCTTTTCTCCTA AAGCTTTTATTTAACAGTGCAAAAGGATCGTTTTTTTTTGCTTTTTTAAACTTGAATTTTTTTAATTTA CACTTTTTAGTTTTAATTTTCTTGTATATTTTGCTAGCTATGAGCTTTTAAATAAAATTGAAAGTTCTG GAAAAGTTTGAAATAATGACATAAAAAGAAGCCTTCTTTTTCTGAGACAGCTTGTCTGGTAAGTGGCTT CTCTGTGAATTGCCTGTAACACATAGTGGCTTCTCCGCCCTTGTAAGGTGTTCAGTAGAGCTAAATAAA TGTAATAGCCAAACCCACTCTGTTGGTAGCAATTGGCAGCCCTATTTCAGTTTATTTTTTCTTCTGTTT TCTTCTTTTCTTTTTTTAAACAGTAAACCTTAACAGATGCGTTCAGCAGACTGGTTTGCAGTGAATTTT CATTTCTTTCCTTATCACCCCCTTGTTGTAAAAAGCCCAGCACTTGAATTGTTATTACTTTAAATGTTC TGTATTTGTATCTGTTTTTATTAGCCAATTAGTGGGATTTTATGCCAGTTGTTAAAATGAGCATTGATG TACCCATTTTTTAAAAAAGCAAGGCACAGCCTTTGCCCAAAACTGTCATCCTAACGTTTGTCATTCCAG TTTGAGTTAATGTGCTGAGCATTTTTTTAAAAGAAGCTTTGTAATAAAACATTTTTAAAAATTGTCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001130713.3
Synonyms	LEF-1; TCF1ALPHA; TCF7L3; TCF10
Summary	This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Locus ID	51176
MW	47.9

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