DUSP6 (NM_001946) Human 3' UTR Clone

Specifications

Product Data
Product Name	DUSP6 (NM_001946) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	HH19; MKP3; PYST1
ACCN	NM_001946
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC213264 3’UTR clone of NM_001946 The sequence shown below is from the reference sequence of NM_001946. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TACCAGGTGGACTCTCTGCAATCTACGTGAAAGACCCCACACCCCTCCTTGCTGGAATGTGTCTGGCCC TTCAGCAGTTTCTCTTGGCAGCATCAGCTGGGCTGCTTTCTTTGTGTGTGGCCCCAGGTGTCAAAATGA CACCAGCTGTCTGTACTAGACAAGGTTACCAAGTGCGGAATTGGTTAATACTAACAGAGAGATTTGCTC CATTCTCTTTGGAATAACAGGACATGCTGTATAGATACAGGCAGTAGGTTTGCTCTGTACCCATGTGTA CAGCCTACCCATGCAGGGACTGGGATTCGAGGACTTCCAGGCGCATAGGGTAGAACCAAATGATAGGGT AGGAGCATGTGTTCTTTAGGGCCTTGTAAGGCTGTTTCCTTTTGCATCTGGAACTGACTATATAATTGT CTTCAATGAAGACTAATTCAATTTTGCATATAGAGGAGCCAAAGAGAGATTTCAGCTCTGTATTTGTGG TATCAGTTTGGAAAAAAAAATCTGATACTCCATTTGATTATTGTAAATATTTGATCTTGAATCACTTGA CAGTGTTTGTTTGAATTGTGTTTGTTTTTTCCTTTGATGGGCTTAAAAGAAATTATCCAAAGGGAGAAA GAGCAGTATGCCACTTCTTAAAACAGAACAAAACAAAAAAAGAAAATTGTGCTCTTTTCTAATCCAAAG GGTATATTTGCAGCATGCTTGACTTTACCAATTCTGATGACATCTTTACGGACACTATTATCACTAAGA CCTTGTTATGGCGAAGTCTTTAGTCTTTTTCATGTATTTTCCTCATGATTTTTTCTCTTTATGTAGTTT GACTATGCCTTACCTTTGTAAATATTTTTGCTTGTGTTGTCGCAAAGGGGATAATCTGGGAAAGACACC AAATCATGGGCTCACTTTAAAAAAAGAAAGAATAAAAAAACCTTCAGCTGTGCTAAACAGTATATTACC TCTGTATAAAATTCTTCAGGGAGTGTCACCTCAAATGCAATACTTTGGGTTGGTTTCTTTCCTTTAAAA AAATTTGTATAAAACTGGAAGTGTGTGTGTGTGAGCATGGGTACCCATTTGATAAGAGAAATGCATTTG ATTGTGAAGAAGGGAGAGTTAAATTCTCCATTATGTTCGTGGTGTAAAGTTTAGAGCTGGAATTTATTA TAAGAATGTAAAACCTTAAATTATTAATAAATAACTATTTTGGCTATTGAATGTGTGTTTTTAAAAACT CAGTTATACCTATGTGTGAAGTGACACATTTTAGAACTTTTTCATTCAGGGATTGATTTTGACTTGTAG GCATAGTAGGGCAAGGTTCTTTTAAGCTTTTCCTAGAACGTTTTTCAGCAGCAGTTTATGAAATTCATC GTTTGCCACGAATAAAGATGACATCCTAGAATGGACCGACTGTACCGTGTATATGAACAATACCTCTTA TGAGTATAGTTCCGGCTTAAGATTTTAAAGCCCCTGAAGAAAAATGAACCTATAGAGCATAGCTTGCTG AGGAATACAATTTGGATATTAACCACAGAGAGGTGTAGCAGAATACCAAGATGACAGCCACATGTTAAC CTCCTCCCTATCCTTCACTGTCAGGATCTTCTGCTTTATAATGCTGAGATAATGCCAAAGAGGAAGTAG GGATAATTCTTTTTCCAGTCTGTTGTCATGGGCAATTCTACCTGCAGATATCCTAGTGTGAGAATGCTG AATCCAGAATGATGTCTCCACTTTTTCCCCTAGCATGCGCATGGCAAGGCATATCTAAGCTTCCTCACC GTGTCAGGATATGGCTTTAGAATTTTACATTGGCACTTAGGAGGCAACTTTGTCATCCCTGTTGTAATG TGCTTTTTTGTTTAACTGGCTTGGGATGTGGGTCAGAAACCCTTATTGAAACTTGTGGGGATTATTTTA GTTTCTTTTCAAGCTAAAGACTTTATATCTTGCCATTTTTCTTGGGACCTACCCTCTCCTTACCTCAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001946.4
Synonyms	HH19; MKP3; PYST1
Summary	The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Mutations in this gene have been associated with congenital hypogonadotropic hypogonadism. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2014]
Locus ID	1848
MW	77.2

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